RHOJ and ZNF426

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RHOJ	ZNF426
Description		ras homolog family member J	zinc finger protein 426
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Extracellular Exosome	Nucleus
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Protein Kinase Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Angiogenesis Endocytosis Actin Filament Organization Signal Transduction Small GTPase-mediated Signal Transduction Rho Protein Signal Transduction Regulation Of Cell Shape Regulation Of Endothelial Cell Migration Establishment Of Cell Polarity Actin Cytoskeleton Organization Retina Vasculature Morphogenesis In Camera-type Eye Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of Sprouting Angiogenesis	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways		RHOJ GTPase cycle	Generic Transcription Pathway
Drugs
Diseases
GWAS		Endometriosis ( 28881265) Heel bone mineral density ( 30598549) Metabolite levels ( 23823483)	Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
Interacting Genes		22 interacting genes: ACVR1 ADAMTSL4 BHLHE40 BLZF1 BMPR1B CDC42 DOCK10 DOCK8 GOLGA2 MEOX2 PAK1 PAK3 PAK5 PAK6 PARD6B SMAD2 SMAD4 SSX3 TGFBR1 TRIP10 WAS ZNF426	45 interacting genes: ACTN3 ANKRD11 ARMC7 ATPAF2 BYSL CALCOCO2 CARD9 CCDC85B CCNC CDK18 CEP70 CIB3 CTNNA3 DUSP4 EFEMP2 ENKD1 FAM161A GLRX3 GSDMD HEXIM2 KCTD9 KRT3 KRTAP4-12 LNX1 LONRF1 LPXN LZTS2 MAGOHB MALSU1 MAP2K5 MDFI MPPE1 MTUS2 NATD1 NINL OPTN PARVG RFC5 RHOJ TEKT4 TSGA10 USP25 ZGPAT ZNF330 ZSCAN23
Entrez ID		57381	79088
HPRD ID		09632	15787
Ensembl ID		ENSG00000126785	ENSG00000130818
Uniprot IDs		Q7Z513 Q9H4E5	K7EME3 K7ER43 Q59EH4 Q9BUY5
PDB IDs
Enriched GO Terms of Interacting Partners?		SMAD Binding Transforming Growth Factor Beta Receptor Activity, Type I Activin Receptor Signaling Pathway Transmembrane Receptor Protein Serine/threonine Kinase Activity Pattern Specification Process Protein Serine/threonine Kinase Activity Anatomical Structure Morphogenesis Cell Migration Ameboidal-type Cell Migration Positive Regulation Of Epithelial To Mesenchymal Transition Regionalization Cell Projection Morphogenesis Neuron Projection Morphogenesis I-SMAD Binding Dendritic Spine Morphogenesis Protein Kinase Activity Regulation Of Cell Motility Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Cell Motility Roof Of Mouth Development Regulation Of Locomotion Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Cell Projection Organization Regulation Of Actin Cytoskeleton Organization Intracellular Signal Transduction Activin Responsive Factor Complex Regulation Of Actin Filament-based Process Intracellular Signaling Cassette Regulation Of Stress Fiber Assembly Regulation Of Supramolecular Fiber Organization Kinase Activity Cellular Response To BMP Stimulus Transforming Growth Factor Beta Receptor Signaling Pathway Dendritic Spine Organization Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Enzyme-linked Receptor Protein Signaling Pathway Regulation Of Epithelial To Mesenchymal Transition Regulation Of Cell Migration Ventricular Septum Morphogenesis Regulation Of Actin Filament Organization Positive Regulation Of SMAD Protein Signal Transduction Tissue Development Neuron Projection Organization Postsynapse Organization Gastrulation Activin Receptor Complex Activin Receptor Activity, Type I SMAD Protein Complex Trophoblast Cell Migration Positive Regulation Of Stress Fiber Assembly
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