RPL38 and CHMP5

Number of citations of the paper that reports this interaction (PMID 16730941)
46

Data Source:
HPRD (two hybrid)

		RPL38	CHMP5
Gene Name		ribosomal protein L38	charged multivesicular body protein 5
Image
Gene Ontology Annotations	Cellular Component	Cytosol Focal Adhesion Cytosolic Large Ribosomal Subunit Eukaryotic 80S Initiation Complex	Nucleus Cytosol Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	RNA Binding Structural Constituent Of Ribosome	Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Skeletal System Development Ossification Translation Translational Initiation Translational Elongation Translational Termination Regulation Of Translation SRP-dependent Cotranslational Protein Targeting To Membrane Sensory Perception Of Sound Gene Expression Viral Process Viral Life Cycle Viral Transcription 90S Preribosome Assembly Middle Ear Morphogenesis Cellular Protein Metabolic Process Axial Mesoderm Development	Cell Separation After Cytokinesis Regulation Of Receptor Recycling Nucleus Organization Lysosome Organization Mitotic Metaphase Plate Congression Endosome To Lysosome Transport Regulation Of Centrosome Duplication Protein Transport Viral Process Endosomal Transport Viral Life Cycle Membrane Organization Regulation Of Mitotic Spindle Assembly
Pathways		Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS			Erectile dysfunction and prostate cancer treatment ( 20932654)
Protein-Protein Interactions		2 interactors: AP2M1 CHMP5	15 interactors: APPBP2 CHMP1B CHMP4A CHMP4B GTF3A MITD1 PDCD10 RPL38 SMARCA4 STAMBP URGCP VPS4B VTA1 ZNF142 ZNF91
Entrez ID		6169	51510
HPRD ID		16048	15408
Ensembl ID		ENSG00000172809	ENSG00000086065
Uniprot IDs		P63173	Q9NZZ3
PDB IDs		3J3B	2LXM 3ULY 3UM0 3UM1 3UM2
Enriched GO Terms of Interacting Partners?		Viral Process Regulation Of Mitotic Spindle Assembly Regulation Of Spindle Assembly Regulation Of Mitotic Spindle Organization Membrane Organization Cell Separation After Cytokinesis Negative Regulation Of Protein Localization To Plasma Membrane Regulation Of Defense Response To Virus By Virus Mitotic Metaphase Plate Congression Regulation Of Receptor Recycling Endosome To Lysosome Transport Metaphase Plate Congression Clathrin-mediated Endocytosis Regulation Of Centrosome Duplication Protein Transport Establishment Of Chromosome Localization Lysosomal Transport Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Establishment Of Protein Localization Regulation Of Centrosome Cycle Negative Regulation Of ERBB Signaling Pathway Intracellular Transport Regulation Of Protein Localization To Plasma Membrane Lysosome Organization Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Mitotic Sister Chromatid Segregation Protein Localization Vacuolar Transport Regulation Of Cellular Component Organization Regulation Of ERBB Signaling Pathway Regulation Of Defense Response To Virus Establishment Of Localization In Cell Sister Chromatid Segregation Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Ephrin Receptor Signaling Pathway Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Vacuole Organization Nucleus Organization Regulation Of Mitotic Nuclear Division Cellular Localization Regulation Of Microtubule Cytoskeleton Organization Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Microtubule-based Process Viral Life Cycle Regulation Of Signaling Endosomal Transport Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway	Cell Separation After Cytokinesis Mitotic Metaphase Plate Congression Metaphase Plate Congression Viral Budding Via Host ESCRT Complex Regulation Of Mitotic Spindle Assembly Establishment Of Chromosome Localization Viral Budding Regulation Of Spindle Assembly Regulation Of Mitotic Spindle Organization Viral Life Cycle Cell Division Mitotic Sister Chromatid Segregation Sister Chromatid Segregation Virion Assembly Nucleus Organization Negative Regulation Of Autophagic Vacuole Assembly Establishment Of Organelle Localization Mitotic Cell Cycle Process Regulation Of Centrosome Duplication Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Centrosome Cycle Mitotic Cell Cycle Organelle Localization Endosomal Transport Cell Cycle Posttranslational Protein Targeting To Membrane Positive Regulation Of Viral Release From Host Cell Establishment Of Localization In Cell Protein Transport Chromosome Segregation Positive Regulation Of Viral Process Establishment Of Protein Localization Vacuolar Transport Viral Process Membrane Budding Intracellular Transport Cell Cycle Process Negative Regulation Of Macroautophagy Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Cellular Localization Mitotic Nuclear Division Cytokinesis Regulation Of Autophagic Vacuole Assembly Regulation Of Mitotic Nuclear Division Regulation Of Vacuole Organization Protein Localization To Endoplasmic Reticulum Protein Localization Regulation Of Viral Release From Host Cell Regulation Of Microtubule Cytoskeleton Organization
Tagcloud ?			associate avian beyond budding coactivator conjugation dimer e3 endosome escrt evolved fusions gag hexamer homologue inability interferes isg15 leukosis lip5 probable rescued retroviruses sarcoma scission sorting tsg101 ubiquitin vps4
Tagcloud (Difference) ?			associate avian beyond budding coactivator conjugation dimer e3 endosome escrt evolved fusions gag hexamer homologue inability interferes isg15 leukosis lip5 probable rescued retroviruses sarcoma scission sorting tsg101 ubiquitin vps4
Tagcloud (Intersection) ?