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ERO1LB and P4HB
Number of citations of the paper that reports this interaction (PMID
11847130
)
38
Data Source:
HPRD
(in vivo)
ERO1LB
P4HB
Gene Name
ERO1-like beta (S. cerevisiae)
prolyl 4-hydroxylase, beta polypeptide
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Extracellular Region
Endoplasmic Reticulum
Endoplasmic Reticulum Lumen
Endoplasmic Reticulum-Golgi Intermediate Compartment
Plasma Membrane
Focal Adhesion
Procollagen-proline 4-dioxygenase Complex
Melanosome
Extracellular Vesicular Exosome
Molecular Function
Protein Disulfide Isomerase Activity
Protein Binding
Protein Disulfide Oxidoreductase Activity
Oxidoreductase Activity
Oxidoreductase Activity, Acting On A Sulfur Group Of Donors, Disulfide As Acceptor
Unfolded Protein Binding
Protein Disulfide Isomerase Activity
Endopeptidase Activity
Procollagen-proline 4-dioxygenase Activity
Protein Binding
Enzyme Binding
Poly(A) RNA Binding
Protein Heterodimerization Activity
Biological Process
Protein Folding
4-hydroxyproline Metabolic Process
Protein Maturation By Protein Folding
Insulin Processing
Extracellular Matrix Organization
Glucose Homeostasis
Cell Redox Homeostasis
Oxidation-reduction Process
Response To Reactive Oxygen Species
Protein Folding
Proteolysis
Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline
Extracellular Matrix Organization
Response To Endoplasmic Reticulum Stress
Lipoprotein Metabolic Process
Small Molecule Metabolic Process
Cell Redox Homeostasis
Cellular Response To Hypoxia
Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways
Peptide hormone metabolism
Insulin processing
Lipoprotein metabolism
Hedgehog ligand biogenesis
Metabolism of lipids and lipoproteins
Collagen formation
Chylomicron-mediated lipid transport
Processing-defective Hh variants abrogate ligand secretion
Detoxification of Reactive Oxygen Species
Lipid digestion, mobilization, and transport
Signaling by Hedgehog
Collagen biosynthesis and modifying enzymes
Drugs
Diseases
GWAS
Protein-Protein Interactions
3 interactors:
BRCA1
ERP44
P4HB
17 interactors:
CD1D
COL10A1
COL1A1
COL1A2
CSNK2A2
EIF2S1
ERO1L
ERO1LB
FEZ1
HNRNPD
P4HA2
P4HA3
PRNP
PTN
TG
UBQLN1
YWHAG
Entrez ID
56605
5034
HPRD ID
13279
07181
Ensembl ID
ENSG00000086619
ENSG00000185624
Uniprot IDs
Q86YB8
B3KTQ9
B4DUA5
F5H8J2
P07237
PDB IDs
1BJX
1MEK
1X5C
2BJX
2K18
3BJ5
3UEM
4EKZ
4EL1
Enriched GO Terms of Interacting Partners
?
Cell Redox Homeostasis
Positive Regulation Of Histone H4-K20 Methylation
Positive Regulation Of Histone H4-K16 Acetylation
Response To Endoplasmic Reticulum Stress
Positive Regulation Of Histone H3-K9 Acetylation
Cellular Response To Stress
Positive Regulation Of Histone H4 Acetylation
Negative Regulation Of Histone H3-K4 Methylation
Protein Folding
Cellular Response To Indole-3-methanol
Negative Regulation Of Centriole Replication
Dosage Compensation By Inactivation Of X Chromosome
Protein K6-linked Ubiquitination
Regulation Of Histone H3-K9 Acetylation
Negative Regulation Of Histone H3-K9 Methylation
Positive Regulation Of Histone H3-K9 Methylation
Dosage Compensation
Regulation Of Centriole Replication
Positive Regulation Of Histone H3-K4 Methylation
Regulation Of Histone H4 Acetylation
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator
Negative Regulation Of Fatty Acid Biosynthetic Process
Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline
DNA Damage Response, Signal Transduction Resulting In Transcription
Monocarboxylic Acid Metabolic Process
Negative Regulation Of Histone Methylation
Negative Regulation Of Centrosome Duplication
Regulation Of DNA Methylation
Negative Regulation Of Histone Acetylation
Positive Regulation Of Histone Acetylation
Negative Regulation Of Peptidyl-lysine Acetylation
Regulation Of Histone H3-K4 Methylation
Negative Regulation Of Protein Acetylation
Positive Regulation Of Peptidyl-lysine Acetylation
Cellular Homeostasis
4-hydroxyproline Metabolic Process
Positive Regulation Of Protein Acetylation
Postreplication Repair
Regulation Of Transcription From RNA Polymerase III Promoter
Negative Regulation Of Fatty Acid Metabolic Process
Regulation Of Gene Expression By Genetic Imprinting
Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Response To Stress
Peptidyl-proline Hydroxylation
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Protein Hydroxylation
Genetic Imprinting
Regulation Of Fatty Acid Biosynthetic Process
Positive Regulation Vascular Endothelial Growth Factor Production
G2 DNA Damage Checkpoint
4-hydroxyproline Metabolic Process
Extracellular Matrix Organization
Extracellular Structure Organization
Collagen Catabolic Process
Protein Maturation By Protein Folding
Cellular Modified Amino Acid Metabolic Process
Collagen Metabolic Process
Multicellular Organismal Macromolecule Metabolic Process
Protein Heterotrimerization
Multicellular Organismal Metabolic Process
Extracellular Matrix Disassembly
Peptidyl-proline Hydroxylation
Protein Hydroxylation
System Development
Response To Endoplasmic Reticulum Stress
Developmental Process
Protein Trimerization
Protein Maturation
Endochondral Ossification
Multicellular Organismal Development
Anatomical Structure Development
Skin Morphogenesis
Antigen Processing And Presentation, Endogenous Lipid Antigen Via MHC Class Ib
Cellular Response To Fluoride
Cellular Response To Amino Acid Stimulus
Collagen Fibril Organization
Alpha-amino Acid Metabolic Process
Ossification
Cellular Response To Organic Substance
Biomineral Tissue Development
Locomotion
Response To Fluoride
Tooth Eruption
Cellular Response To Stimulus
Endochondral Bone Morphogenesis
Regulation Of Cellular Protein Metabolic Process
Endoplasmic Reticulum Unfolded Protein Response
Cellular Response To Unfolded Protein
Response To Stimulus
Axon Guidance
ER-nucleus Signaling Pathway
Cellular Response To Topologically Incorrect Protein
Negative Regulation Of Calcineurin-NFAT Signaling Cascade
Regulation Of Protein Metabolic Process
Movement Of Cell Or Subcellular Component
Response To Amino Acid
Response To Oxidative Stress
Protein Oligomerization
Cell Redox Homeostasis
Bone Morphogenesis
Tagcloud
?
anchor
anchorage
artificial
assign
bac
backcross
bacs
bands
bovine
bta19
centromere
chrnb1
chromosomes
colour
construct
cryb1
fish
gh1
hybrid
interspecies
library
linkage
locations
loci
map
meiotic
nf1
tp53
unresolved
Tagcloud (Difference)
?
anchor
anchorage
artificial
assign
bac
backcross
bacs
bands
bovine
bta19
centromere
chrnb1
chromosomes
colour
construct
cryb1
fish
gh1
hybrid
interspecies
library
linkage
locations
loci
map
meiotic
nf1
tp53
unresolved
Tagcloud (Intersection)
?