ERO1LB and ERP44

Number of citations of the paper that reports this interaction (PMID 11847130)
38

Data Source:
HPRD (in vivo)

		ERO1LB	ERP44
Gene Name		ERO1-like beta (S. cerevisiae)	endoplasmic reticulum protein 44
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane	Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Cell Surface Extracellular Vesicular Exosome
	Molecular Function	Protein Disulfide Isomerase Activity Protein Binding Protein Disulfide Oxidoreductase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On A Sulfur Group Of Donors, Disulfide As Acceptor Unfolded Protein Binding	Protein Disulfide Isomerase Activity Protein Binding
	Biological Process	Protein Folding 4-hydroxyproline Metabolic Process Protein Maturation By Protein Folding Insulin Processing Extracellular Matrix Organization Glucose Homeostasis Cell Redox Homeostasis Oxidation-reduction Process	Protein Folding Response To Unfolded Protein Glycoprotein Metabolic Process Response To Endoplasmic Reticulum Stress Cell Redox Homeostasis
Pathways		Peptide hormone metabolism Insulin processing
Drugs
Diseases
GWAS			Preeclampsia ( 23551011)
Protein-Protein Interactions		3 interactors: BRCA1 ERP44 P4HB	3 interactors: ERO1L ERO1LB ITPR1
Entrez ID		56605	23071
HPRD ID		13279	10290
Ensembl ID		ENSG00000086619	ENSG00000023318
Uniprot IDs		Q86YB8	Q9BS26
PDB IDs			2R2J
Enriched GO Terms of Interacting Partners?		Cell Redox Homeostasis Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Response To Endoplasmic Reticulum Stress Positive Regulation Of Histone H3-K9 Acetylation Cellular Response To Stress Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Protein Folding Cellular Response To Indole-3-methanol Negative Regulation Of Centriole Replication Dosage Compensation By Inactivation Of X Chromosome Protein K6-linked Ubiquitination Regulation Of Histone H3-K9 Acetylation Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation Regulation Of Centriole Replication Positive Regulation Of Histone H3-K4 Methylation Regulation Of Histone H4 Acetylation DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Negative Regulation Of Fatty Acid Biosynthetic Process Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline DNA Damage Response, Signal Transduction Resulting In Transcription Monocarboxylic Acid Metabolic Process Negative Regulation Of Histone Methylation Negative Regulation Of Centrosome Duplication Regulation Of DNA Methylation Negative Regulation Of Histone Acetylation Positive Regulation Of Histone Acetylation Negative Regulation Of Peptidyl-lysine Acetylation Regulation Of Histone H3-K4 Methylation Negative Regulation Of Protein Acetylation Positive Regulation Of Peptidyl-lysine Acetylation Cellular Homeostasis 4-hydroxyproline Metabolic Process Positive Regulation Of Protein Acetylation Postreplication Repair Regulation Of Transcription From RNA Polymerase III Promoter Negative Regulation Of Fatty Acid Metabolic Process Regulation Of Gene Expression By Genetic Imprinting Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Response To Stress Peptidyl-proline Hydroxylation Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Protein Hydroxylation Genetic Imprinting Regulation Of Fatty Acid Biosynthetic Process Positive Regulation Vascular Endothelial Growth Factor Production G2 DNA Damage Checkpoint	Protein Maturation By Protein Folding 4-hydroxyproline Metabolic Process Release Of Sequestered Calcium Ion Into Cytosol Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Protein Maturation Regulation Of Sequestering Of Calcium Ion Calcium Ion Transport Into Cytosol Cytosolic Calcium Ion Transport Cellular Homeostasis Chemical Homeostasis Cell Redox Homeostasis Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Endoplasmic Reticulum Stress Regulation Of Ion Homeostasis Cytosolic Calcium Ion Homeostasis Intrinsic Apoptotic Signaling Pathway Homeostatic Process Oxidation-reduction Process Cellular Modified Amino Acid Metabolic Process Alpha-amino Acid Metabolic Process Protein Folding Cellular Calcium Ion Homeostasis Voluntary Musculoskeletal Movement Calcium Ion Homeostasis Calcium Ion Transport Apoptotic Signaling Pathway Insulin Processing Extracellular Matrix Organization Extracellular Structure Organization Cellular Metal Ion Homeostasis Small Molecule Metabolic Process Negative Regulation Of Calcium-mediated Signaling Cellular Cation Homeostasis Cellular Ion Homeostasis Cellular Amino Acid Metabolic Process Metal Ion Homeostasis Insulin Metabolic Process Cellular Chemical Homeostasis Ion Homeostasis Monocarboxylic Acid Metabolic Process Inositol Phosphate-mediated Signaling Cytoplasmic Transport Chaperone Mediated Protein Folding Requiring Cofactor Metal Ion Transport Peptide Hormone Processing Endoplasmic Reticulum Calcium Ion Homeostasis Apoptotic Process Programmed Cell Death Brown Fat Cell Differentiation Regulation Of Calcium-mediated Signaling
Tagcloud ?			calnexin calreticulin catalysed desirable disulphide erdj5 erp57 erp72 grp78 immunocytochemical immunogens immunolocalization infective isomerase orthologues pdi pdia10 pdia19 pdia2 pdia3 pdia4 pdis spiralis thioredoxin tmx1 tmx2 tmx3 trichinella trimerization
Tagcloud (Difference) ?			calnexin calreticulin catalysed desirable disulphide erdj5 erp57 erp72 grp78 immunocytochemical immunogens immunolocalization infective isomerase orthologues pdi pdia10 pdia19 pdia2 pdia3 pdia4 pdis spiralis thioredoxin tmx1 tmx2 tmx3 trichinella trimerization
Tagcloud (Intersection) ?