ERO1B and ERP44

Number of citations of the paper that reports this interaction (PubMedID 11847130)
46

Data Source:
HPRD (in vivo)

		ERO1B	ERP44
Description		endoplasmic reticulum oxidoreductase 1 beta	endoplasmic reticulum protein 44
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Membrane	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Cell Surface Specific Granule Lumen Extracellular Exosome
	Molecular Function	Protein Binding Protein-disulfide Reductase Activity Disulfide Oxidoreductase Activity Oxidoreductase Activity Thiol Oxidase Activity Unfolded Protein Binding FAD Binding	Protein Disulfide Isomerase Activity Protein Binding
	Biological Process	Protein Folding Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Insulin Processing Extracellular Matrix Organization Protein Folding In Endoplasmic Reticulum Glucose Homeostasis Cell Redox Homeostasis Protein Maturation	Protein Folding Response To Unfolded Protein Glycoprotein Metabolic Process Response To Endoplasmic Reticulum Stress Cell Redox Homeostasis
Pathways		Insulin processing	Neutrophil degranulation
Drugs		1-Ethyl-Pyrrolidine-2,5-Dione Flavin adenine dinucleotide
Diseases
GWAS			Preeclampsia ( 23551011)
Interacting Genes		4 interacting genes: BRCA1 ERP44 OGT P4HB	3 interacting genes: ERO1A ERO1B ITPR1
Entrez ID		56605	23071
HPRD ID		13279	10290
Ensembl ID		ENSG00000086619	ENSG00000023318
Uniprot IDs		Q86YB8	A0A384MEE7 Q9BS26
PDB IDs			2R2J 5GU6 5GU7 5HQP 5XWM
Enriched GO Terms of Interacting Partners?			Calcineurin Complex Thiol Oxidase Activity Protein Folding In Endoplasmic Reticulum Protein-disulfide Reductase Activity Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Cell Redox Homeostasis FAD Binding Endoplasmic Reticulum Membrane Sphingolipid Floppase Activity Release Of Sequestered Calcium Ion Into Cytosol Inositol 1,4,5-trisphosphate Receptor Activity Involved In Regulation Of Postsynaptic Cytosolic Calcium Levels Negative Regulation Of Sequestering Of Calcium Ion Response To Vitamin B3 Positive Regulation Of High-density Lipoprotein Particle Assembly Apolipoprotein A-I Receptor Activity Cytoskeletal Calyx Endoplasmic Reticulum-Golgi Intermediate Compartment Organization
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