AZU1 and CLEC4G

Number of citations of the paper that reports this interaction (PMID 18624398)
4

Data Source:
BioGRID (two hybrid)

		AZU1	CLEC4G
Gene Name		azurocidin 1	C-type lectin domain family 4, member G
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Azurophil Granule Extracellular Vesicular Exosome	Integral Component Of Membrane
	Molecular Function	Serine-type Endopeptidase Activity Heparin Binding Toxic Substance Binding	Protein Binding Carbohydrate Binding
	Biological Process	Microglial Cell Activation Proteolysis Inflammatory Response Immune Response Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Glial Cell Migration Protein Processing Monocyte Activation Positive Regulation Of Tumor Necrosis Factor Biosynthetic Process Negative Regulation Of Apoptotic Process Regulation Of Vascular Permeability Cellular Extravasation Positive Regulation Of MHC Class II Biosynthetic Process Positive Regulation Of Cell Adhesion Macrophage Chemotaxis Positive Regulation Of Interleukin-1 Beta Biosynthetic Process Positive Regulation Of Fractalkine Biosynthetic Process Positive Regulation Of Phagocytosis Defense Response To Gram-negative Bacterium Induction Of Positive Chemotaxis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: CLEC4G TTK	19 interactors: APOA1 APOH ARSA ASGR1 AZU1 CAPN1 COX1 CPN1 EIF6 FTL GEM IFI35 MAP3K11 NUP214 PKLR PRDX1 RPSA SHBG WBP2
Entrez ID		566	339390
HPRD ID		01221	16721
Ensembl ID		ENSG00000172232	ENSG00000182566
Uniprot IDs		P20160	B7ZKQ2 Q08G24 Q6UXB4 Q6XYD1
PDB IDs		1A7S 1AE5 1FY1 1FY3
Enriched GO Terms of Interacting Partners?		Chromosome Separation Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Mitotic Spindle Organization Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Negative Regulation Of Chromosome Organization Negative Regulation Of Protein Catabolic Process Regulation Of Mitotic Nuclear Division Spindle Organization Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Mitotic Cell Cycle Checkpoint Regulation Of Proteasomal Protein Catabolic Process Regulation Of Chromosome Organization Negative Regulation Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Chromosome Segregation Cell Cycle Checkpoint Regulation Of Cell Cycle Phase Transition Regulation Of Cell Division Peptidyl-tyrosine Phosphorylation Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Regulation Of Protein Catabolic Process Regulation Of Protein Processing Regulation Of Mitotic Cell Cycle Microtubule Cytoskeleton Organization Negative Regulation Of Cell Cycle Regulation Of Cell Cycle Process	Positive Regulation Of Lipoprotein Lipase Activity Nuclear Export Ribosome Assembly Response To Extracellular Stimulus Response To Steroid Hormone Response To Organic Cyclic Compound Response To Stimulus Response To Estrogen Response To Nutrient Response To Hormone Regulation Of Interleukin-1 Beta Production Positive Regulation Of Fractalkine Biosynthetic Process Positive Regulation Of Interleukin-1 Beta Biosynthetic Process Negative Regulation Of Cell Adhesion Molecule Production Primary Spermatocyte Growth Nucleocytoplasmic Transport Nuclear Transport RNA Export From Nucleus RRNA Export From Nucleus Endonucleolytic Cleavage To Generate Mature 3'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Negative Regulation Of Interleukin-1 Beta Secretion Positive Regulation Of Histone H3-K14 Acetylation Cellular Localization Catabolic Process Response To Organic Substance Positive Regulation Of Lipase Activity Viral Transcription Negative Regulation Of Very-low-density Lipoprotein Particle Remodeling Cholesterol Import Regulation Of Histone H3-K14 Acetylation Triglyceride Transport Receptor-mediated Endocytosis Lipid Metabolic Process Response To Stress Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Negative Regulation Of Interleukin-1 Secretion Establishment Of Localization In Cell Cellular Process Response To Lipid Bradykinin Catabolic Process RRNA Transport Pyruvate Biosynthetic Process Membrane Organization Response To Nutrient Levels Mature Ribosome Assembly RRNA 3'-end Processing High-density Lipoprotein Particle Clearance Cellular Response To Stimulus RNA Transport Protein Oxidation
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