AZU1 and CLEC4G

Number of citations of the paper that reports this interaction (PubMedID 18624398)
0

Data Source:
BioGRID (two hybrid)

		AZU1	CLEC4G
Description		azurocidin 1	C-type lectin domain family 4 member G
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Membrane Azurophil Granule Membrane Azurophil Granule Lumen Azurophil Granule Extracellular Exosome	Plasma Membrane External Side Of Plasma Membrane Membrane
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding Heparin Binding Peptidase Activity Toxic Substance Binding Heparan Sulfate Proteoglycan Binding	Virus Receptor Activity Protein Binding D-mannose Binding Carbohydrate Binding Polysaccharide Binding Pattern Recognition Receptor Activity Fructose Binding Carbohydrate Derivative Binding Virus Coreceptor Activity Glycosylated Region Protein Binding
	Biological Process	Microglial Cell Activation Proteolysis Chemotaxis Inflammatory Response Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Glial Cell Migration Antimicrobial Humoral Response Positive Regulation Of Fractalkine Production Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Tumor Necrosis Factor Production Intracellular Signal Transduction Monocyte Extravasation Monocyte Activation Defense Response To Bacterium Negative Regulation Of Apoptotic Process Regulation Of Vascular Permeability Cellular Extravasation Positive Regulation Of MHC Class II Biosynthetic Process Positive Regulation Of Cell Adhesion Macrophage Chemotaxis Positive Regulation Of Phagocytosis Defense Response To Gram-negative Bacterium Induction Of Positive Chemotaxis Protein Maturation Defense Response To Virus Cell Chemotaxis Neutrophil-mediated Killing Of Bacterium	T Cell Mediated Immunity Negative Regulation Of T Cell Mediated Immunity Immune Response Immature T Cell Proliferation In Thymus Negative Regulation Of Immature T Cell Proliferation In Thymus Negative Regulation Of T Cell Proliferation Alpha-beta T Cell Proliferation Negative Regulation Of Alpha-beta T Cell Proliferation Symbiont Entry Into Host Cell Positive Regulation Of Viral Life Cycle
Pathways		Neutrophil degranulation	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)	Post bronchodilator FEV1 ( 26634245)
Interacting Genes		2 interacting genes: CLEC4G TTK	27 interacting genes: APOA1 APOH ARL13B ARSA ASGR1 AZU1 CAPN1 CPLX4 CPN1 EBAG9 EIF6 FAM209A FTL GEM IFI35 LRRC4C MAP3K11 MT-CO1 NUP214 PKLR PRDX1 PTPN5 RPSA SHBG SIGLEC12 TNFAIP3 WBP2
Entrez ID		566	339390
HPRD ID		01221	16721
Ensembl ID		ENSG00000172232	ENSG00000182566
Uniprot IDs		P20160	B7ZKQ2 Q08G24 Q6UXB4 Q6XYD1
PDB IDs		1A7S 1AE5 1FY1 1FY3
Enriched GO Terms of Interacting Partners?		Meiotic Spindle Assembly Checkpoint Signaling Protein Localization To Meiotic Spindle Midzone Virus Coreceptor Activity Repair Of Mitotic Kinetochore Microtubule Attachment Defect Meiotic Spindle Checkpoint Signaling Negative Regulation Of Metaphase/anaphase Transition Of Meiotic Cell Cycle Glycosylated Region Protein Binding Female Meiosis Chromosome Segregation Kinetochore Binding Negative Regulation Of Immature T Cell Proliferation In Thymus Negative Regulation Of Immature T Cell Proliferation Immature T Cell Proliferation In Thymus Negative Regulation Of Meiotic Cell Cycle Phase Transition Fructose Binding Meiotic Cell Cycle Checkpoint Signaling Carbohydrate Derivative Binding Negative Regulation Of T Cell Differentiation In Thymus Protein Localization To Kinetochore Polysaccharide Binding Regulation Of Immature T Cell Proliferation In Thymus Meiotic Chromosome Segregation Alpha-beta T Cell Proliferation Negative Regulation Of Alpha-beta T Cell Proliferation Negative Regulation Of Meiotic Cell Cycle D-mannose Binding Regulation Of T Cell Differentiation In Thymus Positive Regulation Of Viral Life Cycle Protein Serine/threonine/tyrosine Kinase Activity Mitotic Spindle Assembly Checkpoint Signaling Negative Regulation Of Mitotic Metaphase/anaphase Transition T Cell Mediated Immunity Negative Regulation Of T Cell Mediated Immunity Negative Regulation Of Mitotic Nuclear Division Protein Localization To Chromosome, Centromeric Region Pattern Recognition Receptor Activity Positive Regulation Of SMAD Protein Signal Transduction Protein Localization To Cytoskeleton Negative Regulation Of Alpha-beta T Cell Activation Nuclear Chromosome Segregation Negative Regulation Of T Cell Differentiation Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Lymphocyte Differentiation Positive Regulation Of Viral Process Regulation Of SMAD Protein Signal Transduction Regulation Of Meiotic Cell Cycle Negative Regulation Of Reproductive Process Regulation Of Chromosome Separation Negative Regulation Of T Cell Proliferation T Cell Proliferation Negative Regulation Of Adaptive Immune Response	Extracellular Exosome
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