AZU1

Gene Name		azurocidin 1
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Gene Ontology Annotations	Cellular Component	Extracellular Region Azurophil Granule Extracellular Vesicular Exosome
	Molecular Function	Serine-type Endopeptidase Activity Heparin Binding Toxic Substance Binding
	Biological Process	Microglial Cell Activation Proteolysis Inflammatory Response Immune Response Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Glial Cell Migration Protein Processing Monocyte Activation Positive Regulation Of Tumor Necrosis Factor Biosynthetic Process Negative Regulation Of Apoptotic Process Regulation Of Vascular Permeability Cellular Extravasation Positive Regulation Of MHC Class II Biosynthetic Process Positive Regulation Of Cell Adhesion Macrophage Chemotaxis Positive Regulation Of Interleukin-1 Beta Biosynthetic Process Positive Regulation Of Fractalkine Biosynthetic Process Positive Regulation Of Phagocytosis Defense Response To Gram-negative Bacterium Induction Of Positive Chemotaxis
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: CLEC4G TTK
Entrez ID		566
HPRD ID		01221
Ensembl ID		ENSG00000172232
Uniprot IDs		P20160
PDB IDs		1A7S 1AE5 1FY1 1FY3
Enriched GO Terms of Interacting Partners?		Chromosome Separation Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Mitotic Spindle Organization Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Negative Regulation Of Chromosome Organization Negative Regulation Of Protein Catabolic Process Regulation Of Mitotic Nuclear Division Spindle Organization Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Mitotic Cell Cycle Checkpoint Regulation Of Proteasomal Protein Catabolic Process Regulation Of Chromosome Organization Negative Regulation Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Chromosome Segregation Cell Cycle Checkpoint Regulation Of Cell Cycle Phase Transition Regulation Of Cell Division Peptidyl-tyrosine Phosphorylation Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Regulation Of Protein Catabolic Process Regulation Of Protein Processing Regulation Of Mitotic Cell Cycle Microtubule Cytoskeleton Organization Negative Regulation Of Cell Cycle Regulation Of Cell Cycle Process
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