PRPS2

Description		phosphoribosyl pyrophosphate synthetase 2
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GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Nucleotide Binding Magnesium Ion Binding Ribose Phosphate Diphosphokinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Identical Protein Binding Protein Homodimerization Activity Metal Ion Binding
	Biological Process	5-phosphoribose 1-diphosphate Biosynthetic Process Pentose-phosphate Shunt Nucleobase-containing Compound Metabolic Process Purine Nucleotide Biosynthetic Process Ribonucleoside Monophosphate Biosynthetic Process Nucleotide Biosynthetic Process
Pathways		5-Phosphoribose 1-diphosphate biosynthesis
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Systemic lupus erythematosus ( 26606652 33272962)
Interacting Genes		4 interacting genes: NOTCH2NLA NTAQ1 PRPSAP1 UBC
Entrez ID		5634
HPRD ID		02414
Ensembl ID		ENSG00000101911
Uniprot IDs		A0A140VK41 P11908
PDB IDs		7YK1 8YI9
Enriched GO Terms of Interacting Partners?		5-phosphoribose 1-diphosphate Biosynthetic Process Protein-N-terminal Asparagine Amidohydrolase Activity Protein-N-terminal Glutamine Amidohydrolase Activity
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