LCA5L and IKBIP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LCA5L	IKBIP
Description		lebercilin LCA5 like	IKBKB interacting protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Axoneme	Nucleolus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Intraciliary Transport	Response To X-ray
Pathways			Regulation of NF-kappa B signaling
Drugs
Diseases
GWAS		Low density lipoprotein cholesterol levels ( 32154731) Pulse pressure ( 30224653) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		19 interacting genes: CCDC136 CCDC197 EXOSC5 FCHSD2 IKBIP KRT75 KRT76 KRT80 KRT81 NMI PBXIP1 PRPH SUV39H2 SYCE1L TFIP11 TPM3 TSGA10IP ZDHHC17 ZGPAT	17 interacting genes: APP BBLN CMTM3 GPR25 KDM1A KRT15 LCA5L MYOG NOD2 NUP62 OGT SMARCD1 SNAPIN TFIP11 TPM3 UBC WASHC3
Entrez ID		150082	121457
HPRD ID		10742	08092
Ensembl ID		ENSG00000157578	ENSG00000166130
Uniprot IDs		O95447 U3KPS7	Q70UQ0
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Constituent Of Skin Epidermis Keratinization Intermediate Filament Keratin Filament Supramolecular Fiber Organization	PTB Domain Binding Cellular Response To Oxygen-containing Compound Regulation Of Cellular Response To Stress Supramolecular Fiber Organization Acetylcholine Receptor Activator Activity Positive Regulation Of Gene Expression, Epigenetic Amyloid-beta Complex Regulation Of Cellular Component Organization Growth Cone Lamellipodium Positive Regulation Of RNA Biosynthetic Process Protein-containing Complex Organization Cytoskeleton-dependent Intracellular Transport Regulation Of Response To Calcium Ion Regulation Of Carbohydrate Catabolic Process Developmental Maturation Regulation Of Glycolytic Process Microtubule-based Transport Transport Along Microtubule Amylin Binding Neuron Maturation Positive Regulation Of RNA Metabolic Process Positive Regulation Of Toll Signaling Pathway Cellular Response To CAMP Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Interleukin-1 Beta Production Lipoprotein Particle Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Chromatin Binding Positive Regulation Of Protein Import Positive Regulation Of DNA-templated Transcription Positive Regulation Of Muscle Atrophy Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Positive Regulation Of Myoblast Differentiation Positive Regulation Of Stem Cell Population Maintenance Regulation Of Double-strand Break Repair Protein-containing Complex Disassembly Regulation Of DNA Repair Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Regulation Of Protein Ubiquitination Regulation Of Post-translational Protein Modification Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Positive Regulation Of Late Endosome To Lysosome Transport Hsp90 Protein Binding Hsp70 Protein Binding Spliceosomal Complex Disassembly Detection Of Muramyl Dipeptide Detection Of Peptidoglycan Muramyl Dipeptide Binding
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