PURB

Gene Name		purine-rich element binding protein B
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm DNA Replication Factor A Complex
	Molecular Function	Double-stranded DNA Binding Single-stranded DNA Binding Sequence-specific DNA Binding Transcription Factor Activity MRNA Binding Transcription Factor Binding Poly(A) RNA Binding SMAD Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Regulation Of Myeloid Cell Differentiation
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: CSNK2A1 IL7R PURA
Entrez ID		5814
HPRD ID		12325
Ensembl ID		ENSG00000146676
Uniprot IDs		Q96QR8
PDB IDs
Enriched GO Terms of Interacting Partners?		Interleukin-7-mediated Signaling Pathway Negative Regulation Of T Cell Mediated Cytotoxicity Negative Regulation Of T Cell Mediated Immunity DNA Unwinding Involved In DNA Replication Lymph Node Development Positive Regulation Of T Cell Differentiation In Thymus Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cell Proliferation Regulation Of T Cell Differentiation In Thymus Negative Regulation Of Protein Metabolic Process DNA Replication Initiation Negative Regulation Of Adaptive Immune Response Mitotic Spindle Checkpoint B Cell Proliferation Negative Regulation Of Chromosome Segregation System Development Cell Morphogenesis Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Immunoglobulin Production Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Chaperone-mediated Protein Folding Multicellular Organismal Development Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of DNA Recombination Regulation Of Gene Expression Anatomical Structure Development Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Protein Catabolic Process DNA Duplex Unwinding DNA Geometric Change Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Positive Regulation Of T Cell Differentiation Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Negative Regulation Of Translation Regulation Of T Cell Mediated Cytotoxicity Negative Regulation Of Chromosome Organization Regulation Of Cell Proliferation Positive Regulation Of Lymphocyte Differentiation
Tagcloud ?		5q31 7p13 aml balance bands chromosomes concurrent cooperative del deleted deletions delicate egr functionally hemizygously heterodimers localizes mapping monosomy myelogenous nearly pura q31 segment segregation simultaneous telomeric