PURB and MIR9-2

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		PURB	MIR9-2
Description		purine rich element binding protein B	microRNA 9-2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	RISC Complex
	Molecular Function	MRNA Regulatory Element Binding Translation Repressor Activity RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding DNA-binding Transcription Factor Activity RNA Binding MRNA Binding Protein Binding Purine-rich Negative Regulatory Element Binding SMAD Binding DNA-binding Transcription Factor Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Translation Regulation Of Myeloid Cell Differentiation Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II	MiRNA-mediated Post-transcriptional Gene Silencing
Pathways
Drugs
Diseases
GWAS		Platelet count ( 27863252)	Body mass index ( 26426971) Regular attendance at a religious group ( 29970889)
Interacting Genes		25 interacting genes: AP1M1 CEBPA CSNK2A1 IL7R LNX1 MBD2 MIR128-1 MIR128-2 MIR25 MIR29C MIR31 MIR34B MIR363 MIR7-1 MIR7-3 MIR9-2 MIRLET7A3 MIRLET7G MIRLET7I NABP1 NXF1 PCDHB14 PURA RBFOX2 ZNF497	76 interacting genes: ADARB1 APOBEC3B C1QBP CELF1 CELF2 CPSF7 CRTAP DARS1 DDX1 DDX21 DDX3X DHX36 EIF2AK2 EPRS1 ERAL1 FAM98A FUS GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IGF2BP1 IGF2BP2 IGF2BP3 KNOP1 LARP7 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 MYEF2 NONO NUDT21 PDCD11 PLOD1 PRMT1 PTBP1 PURA PURB QARS1 RARS1 RBFOX2 RBM14 RBM4 RBM4B RBMS2 RTCA RTCB SF3B1 SF3B2 SF3B3 SFPQ SYNCRIP TAF15 TENT2 TIAL1 TRA2A TRA2B UTP20 YBX1 YBX3 ZC3H11A ZFR ZNF346 ZNF385A
Entrez ID		5814	407047
HPRD ID		12325
Ensembl ID		ENSG00000146676	ENSG00000284447
Uniprot IDs		Q96QR8
PDB IDs
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing RISC Complex Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing Post-transcriptional Regulation Of Gene Expression MRNA Base-pairing Post-transcriptional Repressor Activity Negative Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Negative Regulation Of Translation Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation MRNA 3'-UTR Binding Regulation Of Macromolecule Metabolic Process Regulation Of Translation Regulation Of Metabolic Process Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Negative Regulation Of Protein Metabolic Process Regulation Of Cardiac Muscle Hypertrophy In Response To Stress RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Vasculature Development Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Regulation Of Angiogenesis Negative Regulation Of Cell Motility Negative Regulation Of Cell Migration Negative Regulation Of Lipoprotein Transport MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Interleukin-34 Production Negative Regulation Of Cell Cycle Negative Regulation Of Locomotion Regulation Of Cell Population Proliferation	RNA Binding Nucleic Acid Binding RNA Processing MRNA Processing RNA Metabolic Process RNA Splicing MRNA Binding MRNA Metabolic Process Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Metabolic Process Regulation Of RNA Splicing Post-transcriptional Regulation Of Gene Expression Ribonucleoprotein Complex Nucleus MRNA 3'-UTR Binding Nucleoplasm Regulation Of Translation MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Macromolecule Metabolic Process RNA Splicing, Via Transesterification Reactions Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Metabolic Process Spliceosomal Complex Regulation Of Gene Expression Negative Regulation Of Translation Catalytic Step 2 Spliceosome Regulation Of Macromolecule Biosynthetic Process Cytoplasmic Stress Granule Negative Regulation Of RNA Catabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Gene Expression Regulation Of Metabolic Process Negative Regulation Of MRNA Catabolic Process RNA Stabilization Negative Regulation Of Macromolecule Metabolic Process MiRNA Binding Nucleolus Regulation Of RNA Metabolic Process MRNA Stabilization Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Biosynthetic Process Negative Regulation Of Protein Metabolic Process Pre-mRNA Binding Positive Regulation Of Cytoplasmic Translation
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