NDUFA12 and MYO15B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NDUFA12	MYO15B
Description		NADH:ubiquinone oxidoreductase subunit A12	myosin XVB
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Respiratory Chain Complex I
	Molecular Function	Protein Binding NADH Dehydrogenase (ubiquinone) Activity
	Biological Process	Aerobic Respiration Mitochondrial ATP Synthesis Coupled Electron Transport Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport
Pathways		Respiratory electron transport Complex I biogenesis
Drugs		NADH
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Chromosomal aberration frequency (chromosome type) ( 31586183) Coronary artery disease ( 29212778 32469254) Heel bone mineral density x serum urate levels interaction ( 34046847) Myocardial infarction ( 33532862)
Interacting Genes		4 interacting genes: MYO15B SYT4 TMED8 ZNF768	96 interacting genes: ABI2 ADAMTSL4 BEND7 C7orf57 CARD9 CCNC CEP57L1 CFAP68 COIL CRX DNAJA3 DUSP21 ERAS FAM9B FHL2 GAB2 GADD45GIP1 GFAP GINS3 GPRASP3 HOXA1 IHO1 IKZF3 KATNBL1 KCNJ6 KIAA0408 KIF24 KIFC3 KLF4 KLHL12 KRT13 KRT31 KRT34 KRT35 KRT75 LIMS1 MTUS2 MYOZ3 NADSYN1 NBPF19 NDUFA12 NECAB2 NEDD4 NEFL NHSL2 NKAPD1 NOTCH2NLA NR1D2 NUP62 PAK5 PKNOX2 PLEKHA3 PNMA1 PNMA5 POU6F2 PPM1K PRKAR1B RAD54B RBM11 RCN1 RCN3 REL RPH3AL RUNDC3A SAXO4 SLA SORBS3 SPATC1L SPRED2 SSBP4 TCF12 TCF4 TEX13A TFIP11 TLE5 TPRN TRAF2 TRIM14 TRIM27 TRIM29 TRIM54 TSC22D4 UBQLN2 VGLL3 ZBED1 ZBTB10 ZBTB3 ZBTB32 ZBTB8A ZCCHC14 ZMAT1 ZNF114 ZNF438 ZNF774 ZNF837 ZNRD2
Entrez ID		55967	80022
HPRD ID		16781
Ensembl ID		ENSG00000184752	ENSG00000266714
Uniprot IDs		Q9UI09	Q96JP2 Q9H614
PDB IDs		5XTB 5XTD 5XTH 5XTI	2DLP
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Dense Core Granule Exocytosis Negative Regulation Of Retrograde Trans-synaptic Signaling By Neuropeptide Regulation Of Postsynaptic Dense Core Vesicle Exocytosis Negative Regulation Of Short-term Neuronal Synaptic Plasticity Dense Core Granule Membrane Regulation Of Trans-synaptic Signaling By BDNF, Modulating Synaptic Transmission Regulation Of Dense Core Granule Exocytosis Neuronal Dense Core Vesicle Membrane Negative Regulation Of Synaptic Vesicle Exocytosis Negative Regulation Of Calcium Ion-dependent Exocytosis Microvesicle Dense Core Granule Cytoskeletal Transport Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Calcium-dependent Activation Of Synaptic Vesicle Fusion Somatodendritic Compartment Secretory Granule Localization Negative Regulation Of Catecholamine Secretion Dense Core Granule Positive Regulation Of Calcium Ion-dependent Exocytosis Neuronal Dense Core Vesicle Positive Regulation Of Dendrite Extension Calcium Ion Sensor Activity Astrocyte Projection Regulation Of Glutamate Secretion Positive Regulation Of Glutamate Secretion Positive Regulation Of Amino Acid Transport Regulation Of Short-term Neuronal Synaptic Plasticity Positive Regulation Of Vesicle Fusion Regulation Of Dopamine Secretion Exocytic Vesicle Regulation Of Vesicle Fusion Regulation Of Catecholamine Secretion Regulation Of Calcium Ion-dependent Exocytosis Neurotransmitter Secretion Negative Regulation Of Exocytosis Positive Regulation Of Regulated Secretory Pathway Calcium-dependent Phospholipid Binding Regulation Of Synaptic Vesicle Exocytosis	Identical Protein Binding Intermediate Filament Organization Protein Binding Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Supramolecular Fiber Organization Structural Constituent Of Skin Epidermis Intermediate Filament Negative Regulation Of G Protein-coupled Receptor Internalization Regulation Of RNA Metabolic Process Zinc Ion Binding Regulation Of Nucleobase-containing Compound Metabolic Process Keratin Filament DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Axonemal A Tubule Inner Sheath RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding
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