KLHL9 and KLHL20

Number of citations of the paper that reports this interaction (PubMedID 26687681)
0

Data Source:
BioGRID (two hybrid)

		KLHL9	KLHL20
Description		kelch like family member 9	kelch like family member 20
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Midbody Cul3-RING Ubiquitin Ligase Complex	Nucleus Cytoplasm Golgi Apparatus Trans-Golgi Network Cytosol Actin Cytoskeleton PML Body Axon Dendrite Cul3-RING Ubiquitin Ligase Complex Cell Projection Perinuclear Region Of Cytoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Cullin Family Protein Binding	Actin Binding Ubiquitin-protein Transferase Activity Protein Binding Type II Interferon Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Protein Ubiquitination Regulation Of Cytokinesis Cell Division	Golgi To Endosome Transport Cytoskeleton Organization Protein Transport Protein Ubiquitination Response To Interferon-alpha Negative Regulation Of Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein K33-linked Ubiquitination
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Feeling miserable ( 29500382)
Interacting Genes		3 interacting genes: AURKB KLHL20 UBE2D1	81 interacting genes: ABLIM1 ACTA1 AOC1 ARHGAP10 ARHGEF11 ARHGEF12 ARHGEF19 ATG9A BCL6 BECN1 BEX1 BEX2 C1orf216 C21orf58 CASP8AP2 CC2D1A CEP126 CIDEC CIMIP1 CLCNKA COL8A1 CORO7 CRK CRMP1 DMAC2 DUSP21 ECT2 EIF3F ENKD1 EPAS1 ERG28 F13A1 FBLN1 FHL2 FIZ1 GBE1 GBP2 GMCL1 HR IVNS1ABP JMJD1C KLHL38 KLHL9 LMO2 LRIF1 LUC7L2 MESD MTNR1A NECAB3 NEDD9 NISCH NTAQ1 NUDCD3 NUP160 ORC4 PAPPA PDPK1 PGLS PIK3C3 PIN1 PML PNKD POLR3D PRKAG1 PRMT6 RACK1 RANBP3 RECK RFC2 SGTA SLC13A5 SLC3A2 STK16 SUV39H1 SVEP1 TFAP2D TNPO2 ULK1 USP20 VPS54 ZFAT
Entrez ID		55958	27252
HPRD ID		13929	13918
Ensembl ID		ENSG00000198642	ENSG00000076321
Uniprot IDs		Q58EZ4 Q9P2J3	Q9Y2M5
PDB IDs			5YQ4 6GY5 8CIA
Enriched GO Terms of Interacting Partners?		Post-translational Protein Modification Mitotic Sister Chromatid Biorientation Repair Of Mitotic Kinetochore Microtubule Attachment Defect Positive Regulation Of Lateral Attachment Of Mitotic Spindle Microtubules To Kinetochore Protein K33-linked Ubiquitination Type II Interferon Binding Protein Modification Process Protein Polyubiquitination Ubiquitin-protein Transferase Activity Mitotic Cytokinesis Checkpoint Signaling Positive Regulation Of Microtubule Depolymerization Sister Chromatid Biorientation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Positive Regulation Of Mitotic Cytokinesis Regulation Of Metaphase Plate Congression Spindle Midzone Assembly Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Negative Regulation Of B Cell Apoptotic Process Positive Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Mitotic Spindle Midzone Assembly Mitotic Spindle Midzone Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Negative Regulation Of Cytokinesis Chromocenter Regulation Of Mitotic Cytokinesis Positive Regulation Of Attachment Of Spindle Microtubules To Kinetochore Chromosome Passenger Complex Cleavage Furrow Formation Positive Regulation Of Mitotic Sister Chromatid Segregation Protein Localization To Kinetochore Golgi To Endosome Transport Negative Regulation Of Cell Division Modification-dependent Protein Catabolic Process Positive Regulation Of Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of CGAS/STING Signaling Pathway Condensed Chromosome, Centromeric Region Positive Regulation Of Protein Depolymerization Positive Regulation Of Cell Cycle Checkpoint Regulation Of B Cell Apoptotic Process Attachment Of Mitotic Spindle Microtubules To Kinetochore Response To Interferon-alpha Protein Catabolic Process Protein Ubiquitination Regulation Of Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Mitotic Sister Chromatid Separation Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Midbody Abscission Proteolysis Involved In Protein Catabolic Process	Protein Binding Midbody Phagophore Assembly Site Regulation Of Cytokinesis Cytoplasm Cellular Response To Glucose Starvation Phosphatidylinositol 3-kinase Complex, Class III, Type II Phosphatidylinositol 3-kinase Complex, Class III, Type I
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