NXF3 and NXT1

Number of citations of the paper that reports this interaction (PMID 19060904)
157

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (in vitro)

		NXF3	NXT1
Gene Name		nuclear RNA export factor 3	nuclear transport factor 2-like export factor 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear RNA Export Factor Complex	Nuclear Pore Cytoplasm Nuclear Speck
	Molecular Function	Nucleotide Binding MRNA Binding Protein Binding	Protein Binding Ran GTPase Binding
	Biological Process	MRNA Export From Nucleus Poly(A)+ MRNA Export From Nucleus	RNA Export From Nucleus Protein Export From Nucleus
Pathways
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		7 interactors: HNRNPUL1 NUP214 NXF1 NXT1 NXT2 SKIL XPO1	8 interactors: DDOST NXF1 NXF2 NXF3 PAXIP1 RAN STAU1 XPO1
Entrez ID		56000	29107
HPRD ID		02261	16159
Ensembl ID		ENSG00000147206	ENSG00000132661
Uniprot IDs		Q9H4D5	Q9UKK6
PDB IDs			1JKG 1JN5
Enriched GO Terms of Interacting Partners?		RNA Transport RNA Localization Nuclear Export MRNA Transport Protein Export From Nucleus Nucleocytoplasmic Transport Nuclear Transport RNA Export From Nucleus Cytoplasmic Transport MRNA Export From Nucleus Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Protein Transport Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Viral Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Establishment Of Protein Localization Intracellular Transport Transforming Growth Factor Beta Receptor Signaling Pathway Ribosomal Small Subunit Export From Nucleus Protein Localization To Nucleus Gene Expression Protein Localization Regulation Of Cellular Response To Growth Factor Stimulus Cellular Response To Transforming Growth Factor Beta Stimulus Viral Life Cycle Response To Transforming Growth Factor Beta Establishment Of Localization In Cell Intracellular Protein Transport Regulation Of Cell Cycle Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Ribosomal Large Subunit Export From Nucleus Ribosomal Subunit Export From Nucleus Poly(A)+ MRNA Export From Nucleus Cellular Localization Protein Heterotrimerization Cellular Protein Localization Cell Cycle Protein Homotrimerization Transport Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Protein Export From Nucleus Intracellular Transport Of Virus Protein Localization To Organelle Lens Fiber Cell Differentiation Protein Trimerization Mitotic Nuclear Envelope Disassembly Regulation Of Centrosome Duplication Cellular Response To Growth Factor Stimulus	Nuclear Export RNA Localization Nucleocytoplasmic Transport Nuclear Transport Cytoplasmic Transport MRNA Transport RNA Transport Ribosomal Small Subunit Export From Nucleus Cellular Localization MRNA Export From Nucleus RNA Export From Nucleus Intracellular Transport Ribosomal Large Subunit Export From Nucleus Ribosomal Subunit Export From Nucleus Poly(A)+ MRNA Export From Nucleus Establishment Of Localization In Cell Gene Expression Intracellular Transport Of Virus Protein Export From Nucleus Positive Regulation Of Histone H3-K36 Methylation Protein Localization To Organelle Viral Process Positive Regulation By Virus Of Viral Protein Levels In Host Cell Protein Localization To Nucleus Transport Ribosome Biogenesis Viral Life Cycle Intracellular Protein Transport Chorion Development Intracellular MRNA Localization Cellular Protein Complex Localization Ribonucleoprotein Complex Biogenesis Establishment Of Organelle Localization Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Histone H3-K4 Methylation Establishment Of Protein Localization To Organelle Positive Regulation Of DNA-templated Transcription, Initiation Protein Complex Localization Positive Regulation Of Histone Acetylation Positive Regulation Of Viral Genome Replication Regulation Of DNA-templated Transcription, Initiation Regulation Of Histone H3-K4 Methylation Cellular Protein Localization Organelle Localization Protein Targeting Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Isotype Switching Regulation Of Protein Export From Nucleus Positive Regulation Of Protein Acetylation Protein Transport
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