RNF114 and XAF1

Number of citations of the paper that reports this interaction (PMID 25313037)
0

Data Source:
BioGRID (pull down)

		RNF114	XAF1
Gene Name		ring finger protein 114	XIAP associated factor 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Nucleus Cytoplasm	Nucleus Mitochondrion Cytosol
	Molecular Function	Zinc Ion Binding Ligase Activity	Zinc Ion Binding
	Biological Process	Multicellular Organismal Development Spermatogenesis Protein Ubiquitination Cell Differentiation	Apoptotic Process Cytokine-mediated Signaling Pathway Negative Regulation Of Protein Complex Assembly Response To Interferon-beta Type I Interferon Signaling Pathway
Pathways			Interferon Signaling Cytokine Signaling in Immune system Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Psoriasis ( 20953189)
Protein-Protein Interactions		26 interactors: AK5 BMI1 EVI2A MAPK3 RNF38 RPSA TRAF4 TRAF6 TRAIP TRIM52 TRIM55 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2DNL UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2K UBE2U UBE2W UEVLD XAF1	5 interactors: APP CREBBP RNF114 TP53 XIAP
Entrez ID		55905	54739
HPRD ID		10329	06978
Ensembl ID		ENSG00000124226	ENSG00000132530
Uniprot IDs		Q9Y508	B3KPW1 Q6GPH4
PDB IDs			2LXW
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Polyubiquitination Protein Modification By Small Protein Conjugation Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Cellular Protein Modification Process Cellular Protein Metabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Toll-like Receptor Signaling Pathway Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Metabolic Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Macromolecule Catabolic Process Protein Catabolic Process Activation Of Innate Immune Response Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Innate Immune Response Protein K63-linked Ubiquitination Regulation Of Innate Immune Response Positive Regulation Of Protein Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Transferase Activity Positive Regulation Of Ligase Activity Cellular Response To Stress Proteolysis Regulation Of Protein Ubiquitination Regulation Of Ubiquitin-protein Transferase Activity Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Apoptotic Process Cellular Response To Oxygen Levels Programmed Cell Death Histone Ubiquitination Catabolic Process Immune Response-regulating Signaling Pathway Cell Death Death Protein Monoubiquitination Innate Immune Response	Notch Signaling Pathway Copper Ion Homeostasis Negative Regulation Of Hydrolase Activity Neuron Apoptotic Process Neuron Death Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Negative Regulation Of Cell Differentiation Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Catalytic Activity Transition Metal Ion Homeostasis Negative Regulation Of Macromitophagy Synaptic Growth At Neuromuscular Junction Positive Regulation Of Protein Linear Polyubiquitination Oligodendrocyte Apoptotic Process Negative Regulation Of Helicase Activity N-terminal Peptidyl-lysine Acetylation Collateral Sprouting In Absence Of Injury Intrinsic Apoptotic Signaling Pathway Apoptotic Process Positive Regulation Of Cellular Metabolic Process Programmed Cell Death Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Peptidyl-tyrosine Phosphorylation Cell Death Death Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Regulation Of Signal Transduction Response To Abiotic Stimulus Regulation Of Cell Cycle Phase Transition Positive Regulation Of Cellular Protein Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Germ-line Stem Cell Maintenance Positive Regulation Of Thymocyte Apoptotic Process Positive Regulation Of Cell Aging Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Endopeptidase Activity Positive Regulation Of Protein Metabolic Process Negative Regulation Of Peptidase Activity Regulation Of Signaling Mitochondrial DNA Repair Axon Choice Point Recognition Positive Regulation Of Cell Cycle Cell Surface Receptor Signaling Pathway Negative Regulation Of Neurogenesis Immune Response Response To Hypoxia
Tagcloud ?			adding complexity decisions determines e3 fail fate favoring feedback finger hipk2 homeodomain inactivated interferes ligase loop preferentially proline siah2 stimulates switch termination ubiquitin ubiquitination uncovers waf1 xiap zinc znf313
Tagcloud (Difference) ?			adding complexity decisions determines e3 fail fate favoring feedback finger hipk2 homeodomain inactivated interferes ligase loop preferentially proline siah2 stimulates switch termination ubiquitin ubiquitination uncovers waf1 xiap zinc znf313
Tagcloud (Intersection) ?