RNF114 and UEVLD

Number of citations of the paper that reports this interaction (PMID 19549727)
40

Data Source:
BioGRID (two hybrid)

		RNF114	UEVLD
Gene Name		ring finger protein 114	UEV and lactate/malate dehyrogenase domains
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Nucleus Cytoplasm	Extracellular Vesicular Exosome
	Molecular Function	Zinc Ion Binding Ligase Activity	Molecular_function Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor
	Biological Process	Multicellular Organismal Development Spermatogenesis Protein Ubiquitination Cell Differentiation	Cellular Protein Modification Process Biological_process Protein Transport Cellular Carbohydrate Metabolic Process Oxidation-reduction Process
Pathways
Drugs
Diseases
GWAS		Psoriasis ( 20953189)
Protein-Protein Interactions		26 interactors: AK5 BMI1 EVI2A MAPK3 RNF38 RPSA TRAF4 TRAF6 TRAIP TRIM52 TRIM55 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2DNL UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2K UBE2U UBE2W UEVLD XAF1	6 interactors: DTX3 LRSAM1 RNF114 RNF4 TRAF6 UBC
Entrez ID		55905	55293
HPRD ID		10329	15608
Ensembl ID		ENSG00000124226	ENSG00000151116
Uniprot IDs		Q9Y508	B4DIA9 Q8IX04
PDB IDs			2I6T 3DL2
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Polyubiquitination Protein Modification By Small Protein Conjugation Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Cellular Protein Modification Process Cellular Protein Metabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Toll-like Receptor Signaling Pathway Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Metabolic Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Macromolecule Catabolic Process Protein Catabolic Process Activation Of Innate Immune Response Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Innate Immune Response Protein K63-linked Ubiquitination Regulation Of Innate Immune Response Positive Regulation Of Protein Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Transferase Activity Positive Regulation Of Ligase Activity Cellular Response To Stress Proteolysis Regulation Of Protein Ubiquitination Regulation Of Ubiquitin-protein Transferase Activity Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Apoptotic Process Cellular Response To Oxygen Levels Programmed Cell Death Histone Ubiquitination Catabolic Process Immune Response-regulating Signaling Pathway Cell Death Death Protein Monoubiquitination Innate Immune Response	Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Polyubiquitination Protein Autoubiquitination Cellular Protein Modification Process Intracellular Receptor Signaling Pathway Virion Assembly Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Protein K63-linked Ubiquitination Cellular Protein Metabolic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Protein Metabolic Process Toll-like Receptor 4 Signaling Pathway JNK Cascade Ubiquitin-dependent Endocytosis Toll-like Receptor Signaling Pathway T Cell Receptor Signaling Pathway Protein Catabolic Process Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of NF-kappaB Transcription Factor Activity Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Positive Regulation Of Protein Ubiquitination Regulation Of Kinetochore Assembly Antigen Receptor-mediated Signaling Pathway Notch Signaling Pathway Activation Of MAPK Activity Activation Of Innate Immune Response Regulation Of Centromere Complex Assembly Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Innate Immune Response Viral Life Cycle Regulation Of Protein Ubiquitination Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of MAP Kinase Activity Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway
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