XAF1

Gene Name		XIAP associated factor 1
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Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion Cytosol
	Molecular Function	Zinc Ion Binding
	Biological Process	Apoptotic Process Cytokine-mediated Signaling Pathway Negative Regulation Of Protein Complex Assembly Response To Interferon-beta Type I Interferon Signaling Pathway
Pathways		Interferon Signaling Cytokine Signaling in Immune system Interferon alpha/beta signaling
Drugs
Diseases
GWAS
Protein-protein Interactions		5 interactors: APP CREBBP RNF114 TP53 XIAP
Entrez ID		54739
HPRD ID		06978
Ensembl ID		ENSG00000132530
Uniprot IDs		B3KPW1 Q6GPH4
PDB IDs		2LXW
Enriched GO Terms of Interacting Partners?		Notch Signaling Pathway Copper Ion Homeostasis Negative Regulation Of Hydrolase Activity Neuron Apoptotic Process Neuron Death Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Negative Regulation Of Cell Differentiation Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Catalytic Activity Transition Metal Ion Homeostasis Negative Regulation Of Macromitophagy Synaptic Growth At Neuromuscular Junction Positive Regulation Of Protein Linear Polyubiquitination Oligodendrocyte Apoptotic Process Negative Regulation Of Helicase Activity N-terminal Peptidyl-lysine Acetylation Collateral Sprouting In Absence Of Injury Intrinsic Apoptotic Signaling Pathway Apoptotic Process Positive Regulation Of Cellular Metabolic Process Programmed Cell Death Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Peptidyl-tyrosine Phosphorylation Cell Death Death Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Regulation Of Signal Transduction Response To Abiotic Stimulus Regulation Of Cell Cycle Phase Transition Positive Regulation Of Cellular Protein Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Germ-line Stem Cell Maintenance Positive Regulation Of Thymocyte Apoptotic Process Positive Regulation Of Cell Aging Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Endopeptidase Activity Positive Regulation Of Protein Metabolic Process Negative Regulation Of Peptidase Activity Regulation Of Signaling Mitochondrial DNA Repair Axon Choice Point Recognition Positive Regulation Of Cell Cycle Cell Surface Receptor Signaling Pathway Negative Regulation Of Neurogenesis Immune Response Response To Hypoxia
Tagcloud ?		adding complexity decisions determines e3 fail fate favoring feedback finger hipk2 homeodomain inactivated interferes ligase loop preferentially proline siah2 stimulates switch termination ubiquitin ubiquitination uncovers waf1 xiap zinc znf313