ZNF395 and SAP30

Number of citations: 0 (PubMedID 17897615)
Data Source: BioGRID (pull down)

		ZNF395	SAP30
Name		zinc finger protein 395	Sin3A associated protein 30
Structure		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck	Histone Deacetylase Complex Nucleus Nucleoplasm Sin3-type Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding	DNA Binding Transcription Coregulator Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Skeletal Muscle Cell Differentiation Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance
Pathways		None	HDACs deacetylate histones NoRC negatively regulates rRNA expression Potential therapeutics for SARS
GWAS		No GWAS studies recorded	No GWAS studies recorded
Interacting Genes		2 interacting genes: SAP30 WASL	28 interacting genes: BRMS1 BRMS1L CIRSR CYTOR H2AC16 H2BC21 H3-4 H4C16 HBP1 HDAC1 HDAC2 HTT ID3 ING1 MXD1 NCOR1 NCOR2 PCBD1 RBBP4 RBBP7 RBP1 SAMSN1 SAP30BP SIN3A UHRF1 VHL YY1 ZNF395
Entrez ID		55893	8819
HPRD ID		11711	04540
Ensembl ID		ENSG00000186918	ENSG00000164105
Uniprot IDs		Q7L9C8 Q9H8N7	O75446
PDB IDs		Not available	2KDP
GO Terms Enriched among Interactors		Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Negative Regulation Of Cell Migration Negative Regulation Of Membrane Tubulation Positive Regulation Of Clathrin-dependent Endocytosis Actin Cap Vesicle Transport Along Actin Filament Negative Regulation Of Lymphocyte Migration Regulation Of Plasma Membrane Organization Dendritic Spine Morphogenesis Regulation Of Clathrin-dependent Endocytosis Sin3-type Complex Regulation Of Cell Motility Negative Regulation Of Stem Cell Population Maintenance Regulation Of Locomotion Regulation Of Cell Migration Actin Filament Polymerization GTPase Regulator Activity Vesicle Budding From Membrane Positive Regulation Of Filopodium Assembly Dendritic Spine Organization Negative Regulation Of Mononuclear Cell Migration Histone Deacetylase Complex Neuron Projection Organization Postsynapse Organization Regulation Of Filopodium Assembly Positive Regulation Of Stem Cell Population Maintenance Skeletal Muscle Cell Differentiation Vesicle Cytoskeletal Trafficking Negative Regulation Of Leukocyte Migration Actin Polymerization Or Depolymerization Positive Regulation Of Receptor-mediated Endocytosis Spindle Localization Actin Filament-based Movement Regulation Of Lymphocyte Migration Protein-containing Complex Localization Regulation Of Stem Cell Population Maintenance Endocytic Vesicle Membrane Protein Polymerization	Sin3-type Complex Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance Regulation Of Stem Cell Population Maintenance Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Histone Deacetylase Binding Histone Deacetylase Complex Negative Regulation Of RNA Metabolic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Nucleoplasm Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Chromatin Organization Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process NuRD Complex Negative Regulation Of Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Metabolic Process Negative Regulation Of Cell Migration Regulation Of Cell Fate Specification Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Negative Regulation Of Developmental Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Cell Fate Commitment Transcription Corepressor Activity Regulation Of Metabolic Process Negative Regulation Of Signal Transduction Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process ESC/E(Z) Complex Negative Regulation Of Cell Communication Negative Regulation Of Signaling Negative Regulation Of Androgen Receptor Signaling Pathway Heterochromatin Formation Rhythmic Process Transcription Repressor Complex