ZFP64 and LMO2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ZFP64	LMO2
Gene Name		ZFP64 zinc finger protein	LIM domain only 2 (rhombotin-like 1)
Image
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Transcription Factor Complex
	Molecular Function	DNA Binding Metal Ion Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity RNA Polymerase II Activating Transcription Factor Binding RNA Polymerase II Transcription Factor Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding Protein Binding Zinc Ion Binding BHLH Transcription Factor Binding Cofactor Binding E-box Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Positive Regulation Of MRNA Splicing, Via Spliceosome	Multicellular Organismal Development Embryonic Hemopoiesis MRNA Transcription From RNA Polymerase II Promoter Negative Regulation Of Erythrocyte Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Thyroid Hormone Stimulus
Pathways
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis ( 17362836) Subcutaneous adipose tissue ( 22589738)	Cognitive performance ( 19734545)
Protein-Protein Interactions		21 interactors: AEN BARD1 BEGAIN BYSL C14orf1 FAM124A FHL2 LMO2 LNX1 MAFB MFAP1 MTUS2 PBK PPARGC1B SETDB1 TLE1 TRIM41 UNC119 ZBTB9 ZNF513 ZNF70	96 interactors: ABI2 ADAMTSL4 AES AGTRAP AIMP2 ALDH6A1 AXIN1 BANP BEX2 BLZF1 C1orf94 CALCOCO2 CCDC33 CCDC36 CDC25A CDC5L CDX4 CLHC1 CMTM5 CORO1A CORO1C DAZAP2 DBF4B DDIT3 DRAP1 EHMT2 ELF2 ERBB2IP FAM154A FHL3 GATA1 GATA2 GATA3 GFAP GOLGA2 GRB2 HNRNPC HNRNPM HOOK1 IFT43 IKZF3 ISL1 KANK2 KDM5A KIF3B KRT15 KRT40 KRTAP10-7 LDB1 LYL1 LZTS2 MAGEA8 MAPRE1 MAPRE2 MAPRE3 MBIP MLLT4 MRFAP1L1 MTUS2 N4BP2L2 NCAPH2 NHLH1 NIF3L1 NOTCH2NL NUP62 NUTM1 PDE9A PHC2 PRKG1 RBBP8 REL RELA RINT1 RLIM ROCK1 SKP1 SMAD2 SOX5 SP1 SPERT SSX2IP STAT1 STAT3 STIP1 TAL1 TAL2 TFPT TLX3 TRIM23 TRIM54 TRIP6 TSC22D4 TUFT1 UBE2I ZFP64 ZNF24
Entrez ID		55734	4005
HPRD ID		15728	01586
Ensembl ID		ENSG00000020256	ENSG00000135363
Uniprot IDs		B3KQX0 Q9NPA5 Q9NTW7	P25791
PDB IDs		1X5W 2DMD	2XJY 2XJZ 2YPA
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated Negative Regulation Of Erythrocyte Differentiation Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of Myeloid Cell Differentiation Regulation Of Erythrocyte Differentiation Regulation Of Nitrogen Compound Metabolic Process Gene Expression Trabecula Morphogenesis Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Clathrin-mediated Endocytosis Rhombomere 6 Development Macromolecule Biosynthetic Process Intracellular Steroid Hormone Receptor Signaling Pathway Biosynthetic Process Negative Regulation Of MRNA 3'-end Processing Negative Regulation Of Caveolin-mediated Endocytosis Regulation Of Gene Expression Negative Regulation Of Myeloid Cell Differentiation Regulation Of Transcription From RNA Polymerase II Promoter Brain Segmentation Atrial Cardiac Muscle Cell Development Cytokinesis, Completion Of Separation Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Blastocyst Development Metabolic Process Regulation Of Nucleic Acid-templated Transcription Rhombomere 5 Development Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Response To Radiation Negative Regulation Of Protein Export From Nucleus Regulation Of Caveolin-mediated Endocytosis Positive Regulation Of Gene Expression Organ Development Mitotic Cytokinetic Process Protein K6-linked Ubiquitination Organ Morphogenesis Histone H3-K9 Trimethylation Visual Perception Sensory Perception Of Light Stimulus	Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process RNA Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Developmental Process Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Cellular Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Nitrogen Compound Metabolic Process Cell Cycle Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Organelle Organization Biosynthetic Process Multicellular Organismal Development Positive Regulation Of Metabolic Process Anatomical Structure Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Differentiation Negative Regulation Of Signal Transduction Cell Fate Commitment Definitive Hemopoiesis Regulation Of Cell Differentiation Negative Regulation Of Cell Differentiation Mitotic Cell Cycle Regulation Of Cell Proliferation Negative Regulation Of Signaling
Tagcloud ?		13q 17p 18q 22q 3p 4p 5q 9p dkk gastric heterozygosity hpp1 imc imcs instability intramucosal loh methylated methylations microsatellite mlh msi rassf2a runx3 sall4 sfrp1 smc smcs submucosal	chimeric chromosomal contribution die disruption embryonic encodes erythropoiesis finger hematopoiesis hematopoietic homozygous leukemias lim lineage lineages master null precluded prevents probably reintroduction rescues sac stages tal1 translocations vector yolk
Tagcloud (Difference) ?		13q 17p 18q 22q 3p 4p 5q 9p dkk gastric heterozygosity hpp1 imc imcs instability intramucosal loh methylated methylations microsatellite mlh msi rassf2a runx3 sall4 sfrp1 smc smcs submucosal	chimeric chromosomal contribution die disruption embryonic encodes erythropoiesis finger hematopoiesis hematopoietic homozygous leukemias lim lineage lineages master null precluded prevents probably reintroduction rescues sac stages tal1 translocations vector yolk
Tagcloud (Intersection) ?