DBNDD2 and CSNK1G2

Number of citations of the paper that reports this interaction (PubMedID 16618118)
0

Data Source:
BioGRID (two hybrid)

		DBNDD2	CSNK1G2
Description		dysbindin domain containing 2	casein kinase 1 gamma 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Endoplasmic Reticulum	Nucleus Cytoplasm Cytosol Plasma Membrane Cell Cortex Membrane
	Molecular Function	Protein Binding ATPase Binding	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity
	Biological Process	Negative Regulation Of Protein Kinase Activity Apoptotic Process Regulation Of Signal Transduction Neurogenesis Neuron Projection Development Monoatomic Ion Homeostasis ERK1 And ERK2 Cascade	Protein Phosphorylation Endocytosis Signal Transduction Wnt Signaling Pathway Sphingolipid Biosynthetic Process Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways			Sphingolipid de novo biosynthesis Disassembly of the destruction complex and recruitment of AXIN to the membrane
Drugs			IC261 N-(2-Aminoethyl)-5-Chloroisoquinoline-8-Sulfonamide 5-iodotubercidin
Diseases
GWAS		Malaria ( 31844061)	Body mass index ( 25673413) Coronary artery disease ( 29212778) Periodontitis (stage III/IV grade C) ( 33745150) Red cell distribution width ( 27863252 32888494) Severe insulin-deficient type 2 diabetes ( 34737425)
Interacting Genes		7 interacting genes: AGTR1 CALCOCO2 CSNK1G2 CSNK1G3 LMNA SFRP2 VIPR2	17 interacting genes: APP APPBP2 CERT1 CLSPN DBNDD2 IRS4 KRTAP10-7 MTA1 NCK1 OGT PER1 PPP1R14A RAP1GAP RUNDC3B SMAD3 SNCA WDCP
Entrez ID		55861	1455
HPRD ID		12763	03738
Ensembl ID		ENSG00000244274	ENSG00000133275
Uniprot IDs		Q9BQY9	P78368
PDB IDs			2C47
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway Wnt Signaling Pathway Regulation Of Canonical Wnt Signaling Pathway Angiotensin Type I Receptor Activity Regulation Of Wnt Signaling Pathway Negative Regulation Of Dermatome Development Thermosensory Behavior Phospholipase C-activating Angiotensin-activated Signaling Pathway Bradykinin Receptor Binding Renin-angiotensin Regulation Of Aldosterone Production DNA Double-strand Break Attachment To Nuclear Envelope Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Structural Constituent Of Nuclear Lamina Sclerotome Development Wnt Signaling Pathway Involved In Somitogenesis Negative Regulation Of Embryonic Development Negative Regulation Of Mesodermal Cell Fate Specification Regulation Of Midbrain Dopaminergic Neuron Differentiation Vasoactive Intestinal Polypeptide Receptor Activity Pituitary Adenylate Cyclase-activating Polypeptide Receptor Activity Regulation Of Cellular Component Organization Angiotensin Type II Receptor Activity Maintenance Of Blood Vessel Diameter Homeostasis By Renin-angiotensin Import Into Cell Regulation Of Extrinsic Apoptotic Signaling Pathway Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Lamin Filament Nuclear Pore Localization Cell-cell Signaling Stem Cell Fate Specification Development Of Primary Male Sexual Characteristics Signaling Convergent Extension Involved In Axis Elongation Cell Communication Potassium:chloride Symporter Activity Regulation Of Renal Sodium Excretion Negative Regulation Of Mesenchymal Cell Proliferation Mesodermal Cell Fate Specification Regulation Of Establishment Of Planar Polarity Xenophagy Positive Regulation Of Autophagosome Maturation Postsynaptic Neurotransmitter Receptor Diffusion Trapping Receptor Diffusion Trapping Regulation Of Mesodermal Cell Differentiation Development Of Primary Sexual Characteristics Ammonium Channel Activity Chloride:monoatomic Cation Symporter Activity Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Negative Regulation Of Apoptotic Signaling Pathway	Regulation Of Cell Junction Assembly Regulation Of Phosphorus Metabolic Process Negative Regulation Of MiRNA Transcription Regulation Of Presynapse Organization Insulin Receptor Binding Chemical Homeostasis Negative Regulation Of RNA Biosynthetic Process Regulation Of Long-term Neuronal Synaptic Plasticity Negative Regulation Of Transcription By RNA Polymerase II Response To Growth Factor Ephrin Receptor Binding Regulation Of Protein Metabolic Process Cellular Response To Growth Factor Stimulus Negative Regulation Of RNA Metabolic Process Regulation Of Presynapse Assembly Negative Regulation Of DNA-templated Transcription Amyloid Fibril Formation Regulation Of Neurotransmitter Uptake Regulation Of Generation Of Precursor Metabolites And Energy Cellular Response To Copper Ion Chromatin DNA Binding Negative Regulation Of Protein Catabolic Process Circadian Regulation Of Gene Expression Photoperiodism Entrainment Of Circadian Clock By Photoperiod Entrainment Of Circadian Clock Circadian Rhythm Negative Regulation Of Nucleobase-containing Compound Metabolic Process Microglial Cell Activation Regulation Of Protein Catabolic Process Regulation Of Supramolecular Fiber Organization Leukocyte Activation Involved In Inflammatory Response Regulation Of Synapse Assembly Response To Copper Ion Positive Regulation Of Endocytosis Amyloid-beta Complex Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Protein Metabolic Process Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Response To Endoplasmic Reticulum Stress Locomotory Behavior Positive Regulation Of Nitric Oxide Metabolic Process Negative Regulation Of Lung Blood Pressure Nuclear Mineralocorticoid Receptor Binding Protein Kinase Inhibitor Activity
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