ACTR10 and SLC13A1

Number of citations of the paper that reports this interaction (PubMedID 18407958)
55

Data Source:
BioGRID (protein complementation assay)

		ACTR10	SLC13A1
Description		actin related protein 10	solute carrier family 13 member 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Cytoskeleton Dynactin Complex Azurophil Granule Lumen Axon Cytoplasm Ficolin-1-rich Granule Lumen	Plasma Membrane Membrane Apical Plasma Membrane
	Molecular Function	Protein Binding	Secondary Active Sulfate Transmembrane Transporter Activity Symporter Activity Solute:sodium Symporter Activity Monoatomic Anion:sodium Symporter Activity Sodium:sulfate Symporter Activity Transmembrane Transporter Activity
	Biological Process	Microtubule-based Movement Retrograde Axonal Transport Of Mitochondrion	Monoatomic Ion Transport Sodium Ion Transport Sodium Ion Transmembrane Transport Transmembrane Transport Monoatomic Anion Transmembrane Transport Sulfate Transmembrane Transport
Pathways		MHC class II antigen presentation HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Neutrophil degranulation COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic	Sodium-coupled sulphate, di- and tri-carboxylate transporters
Drugs
Diseases
GWAS		Alcohol consumption ( 31358974) Brain morphology (MOSTest) ( 32665545) High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel) ( 23648065) High density lipoprotein cholesterol levels ( 30498476) Systolic blood pressure ( 30578418)
Interacting Genes		7 interacting genes: ACTA1 DCTN4 HOMEZ KRT31 NAGK RXFP4 SLC13A1	31 interacting genes: ACOT2 ACTR10 APLP2 ARL6IP1 ASS1 CD59 COQ5 COQ9 CRYAB DYNLL1 FTL GRN HSPA1A MKRN1 NDUFS5 NHERF1 NHERF2 OGDHL PDZK1 PNPLA6 PRSS8 RHOA SDHD SEC61A1 SELPLG SERPINA1 TBRG1 TM4SF1 TMED10 TP53I11 TSPAN3
Entrez ID		55860	6561
HPRD ID		12420	08394
Ensembl ID		ENSG00000131966	ENSG00000081800
Uniprot IDs		Q9NZ32	A4D0X1 Q2NKK0 Q9BZW2
PDB IDs			8W6H 8W6N 8W6O 8W6T 8Y5U 8Y5W 8Y5X 8Y5Y 8Y5Z
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Cytoskeleton Sarcomere Stress Fiber Sodium:sulfate Symporter Activity Monoatomic Anion:sodium Symporter Activity N-acetylglucosamine Kinase Activity N-acylmannosamine Kinase Activity N-acetylmannosamine Metabolic Process Muramyl Dipeptide Kinase Activity Skeletal Muscle Thin Filament Assembly Mesenchyme Migration Protein Linear Polyubiquitination Positive Regulation Of Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway N-acetylglucosamine Catabolic Process N-acetylneuraminate Catabolic Process Galanin Receptor Activity Secondary Active Sulfate Transmembrane Transporter Activity Dynactin Complex Striated Muscle Thin Filament Sulfate Transmembrane Transport UDP-N-acetylglucosamine Biosynthetic Process Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway N-acetylneuraminate Metabolic Process Positive Regulation Of Feeding Behavior Solute:sodium Symporter Activity UDP-N-acetylglucosamine Metabolic Process Regulation Of Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway	Extracellular Exosome Type 2 Metabotropic Glutamate Receptor Binding Type 3 Metabotropic Glutamate Receptor Binding Vesicle Protein-membrane Adaptor Activity Sec61 Translocon Complex Ubiquinone Biosynthesis Complex Establishment Of Epithelial Cell Apical/basal Polarity Mitochondrion Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Cellular Localization ATP Metabolic Process Aerobic Electron Transport Chain Cotranslational Protein Targeting To Membrane Ubiquinone Metabolic Process Ubiquinone Biosynthetic Process Azurophil Granule Lumen Quinone Metabolic Process Establishment Of Apical/basal Cell Polarity Signaling Receptor Binding Aerobic Respiration Respiratory Electron Transport Chain Establishment Of Monopolar Cell Polarity Establishment Or Maintenance Of Monopolar Cell Polarity Polarized Epithelial Cell Differentiation Protein Stabilization Electron Transport Chain Cellular Respiration Membrane Angiotensin-mediated Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Establishment Of Epithelial Cell Polarity Mitotic Cleavage Furrow Formation Argininosuccinate Synthase Activity Argininosuccinate Metabolic Process Regulation Of Transport Protein Refolding Positive Regulation Of Aspartic-type Peptidase Activity Purine Ribonucleotide Metabolic Process Purine-containing Compound Metabolic Process Ficolin-1-rich Granule Lumen COP9 Signalosome Microvillus Membrane Tricarboxylic Acid Cycle Renal Phosphate Ion Absorption Protein Transmembrane Transporter Activity Cytosol To ERGIC Protein Transport Protein Localization To ERGIC COPI-coated Vesicle Budding Pronephric Nephron Development Isoprenoid Binding
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