KIZ and TACC3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		KIZ	TACC3
Description		kizuna centrosomal protein	transforming acidic coiled-coil containing protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytoskeleton Cell Projection	Spindle Pole Cytoplasm Golgi Apparatus Centrosome Spindle Cytosol Cytoskeleton Centriolar Satellite Ciliary Basal Body Mitotic Spindle
	Molecular Function	Protein Binding Protein Kinase Binding	Protein Binding
	Biological Process	Spindle Organization	Microtubule Cytoskeleton Organization Mitotic Spindle Organization Metaphase/anaphase Transition Of Mitotic Cell Cycle Nuclear Migration Cerebral Cortex Development Cell Division Regulation Of Mitotic Spindle Organization Microtubule Cytoskeleton Organization Involved In Mitosis
Pathways			NOTCH3 Activation and Transmission of Signal to the Nucleus Negative regulation of NOTCH4 signaling
Drugs
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Appendicular lean mass ( 33097823) Autism spectrum disorder ( 30804558) Height ( 31562340)	Appendicular lean mass ( 33097823) Bladder cancer ( 20972438 24163127) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Hip circumference adjusted for BMI ( 34021172) Mean spheric corpuscular volume ( 32888494) Subcortical volume (MOSTest) ( 32665545) Urinary bladder cancer ( 20348956)
Interacting Genes		4 interacting genes: CRYAA MEOX2 TACC3 TFIP11	30 interacting genes: AKAP9 ARHGDIG ARNT ARNT2 ASPSCR1 AURKA BEX2 BEX3 CATSPERT CCHCR1 CDC20B CDKL5 CIB3 CLIP4 DRC10 EIF3C GDF15 KAT2A KIZ KLC1 KLHL38 NDEL1 NOD2 NUP54 RNF20 SNX20 SPATA18 TBC1D22B TTF2 VPS37C
Entrez ID		55857	10460
HPRD ID		12760	05601
Ensembl ID		ENSG00000088970	ENSG00000013810
Uniprot IDs		A0A087X251 Q2M2Z5	A0A087WUE2 Q9Y6A5
PDB IDs			5LXN 5LXO 5ODS 5ODT
Enriched GO Terms of Interacting Partners?		Protein-containing Complex Organization Ventral Spinal Cord Interneuron Fate Determination Type B Pancreatic Cell Fate Commitment DGTPase Activity DGTP Binding Triphosphoric Monoester Hydrolase Activity Deoxynucleoside Triphosphate Hydrolase Activity Positive Regulation Of Translational Fidelity TRNA-2-methylthio-N(6)-dimethylallyladenosine(37) Synthase Activity	Cytoplasm Aryl Hydrocarbon Receptor Binding Aryl Hydrocarbon Receptor Complex Microtubule-based Process Mitotic Centrosome Separation Centrosome Localization Axon Hillock Centrosome Separation
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