ARHGAP15 and CD93

Number of citations of the paper that reports this interaction (PMID 15459234)
10

Data Source:
HPRD (two hybrid)

		ARHGAP15	CD93
Gene Name		Rho GTPase activating protein 15	CD93 molecule
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Membrane	Plasma Membrane Cell Surface Integral Component Of Membrane Cytoplasmic Membrane-bounded Vesicle
	Molecular Function	Rac GTPase Activator Activity	Complement Component C1q Binding Receptor Activity Calcium Ion Binding Protein Binding Carbohydrate Binding
	Biological Process	Small GTPase Mediated Signal Transduction Regulation Of Cell Shape Positive Regulation Of Rac GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction	Phagocytosis Viral Process Single Organismal Cell-cell Adhesion Macrophage Activation
Pathways		Rho GTPase cycle Signaling by Rho GTPases
Drugs
Diseases
GWAS		Quantitative traits ( 19197348)	Obesity-related traits ( 23251661)
Protein-Protein Interactions		7 interactors: CD93 KDM1A PRNP RAC1 SMURF1 SNCA TGFBR1	23 interactors: ARHGAP15 BAG6 C1QA COL1A1 COL1A2 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COPS5 F12 FAM46A GIPC1 KIR2DL2 KNG1 MBL2 MSN MYD88 RANBP1 SCYL1 UBQLN2
Entrez ID		55843	22918
HPRD ID		06447	00396
Ensembl ID		ENSG00000075884	ENSG00000125810
Uniprot IDs		Q53QZ3	Q9NPY3
PDB IDs		3BYI
Enriched GO Terms of Interacting Partners?		Cellular Response To Copper Ion Regulation Of Hydrogen Peroxide Metabolic Process Negative Regulation Of Signal Transduction Negative Regulation Of Signaling Cellular Response To Growth Factor Stimulus Response To Growth Factor Response To Copper Ion Regulation Of Apoptotic Process Regulation Of Signal Transduction Cell Activation Regulation Of Cell Death Macrophage Activation Regulation Of Signaling Negative Regulation Of Apoptotic Process Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Immune System Process Regulation Of Protein Metabolic Process Regulation Of Protein Phosphorylation Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Receptor Metabolic Process Regulation Of Cell Activation Regulation Of Immune System Process Regulation Of Phosphorylation Positive Regulation Of Kinase Activity Negative Regulation Of Chromosome Organization Negative Regulation Of Thrombin Receptor Signaling Pathway Positive Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Glutathione Peroxidase Activity Regulation Of Primitive Erythrocyte Differentiation Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Norepinephrine Uptake Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Transferase Activity Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Phosphorus Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cell Projection Assembly Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Wound Healing Positive Regulation Of Cell Death Embryonic Olfactory Bulb Interneuron Precursor Migration Negative Regulation Of Interleukin-23 Production Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Regulation Of Histone Modification Cellular Response To Metal Ion	Collagen Catabolic Process Collagen Metabolic Process Multicellular Organismal Macromolecule Metabolic Process Multicellular Organismal Metabolic Process Extracellular Matrix Disassembly Extracellular Matrix Organization Extracellular Structure Organization Locomotion Movement Of Cell Or Subcellular Component Catabolic Process Protein Activation Cascade Axon Guidance Cellular Response To Amino Acid Stimulus Vesicle-mediated Transport Regulation Of Protein Processing Protein Heterotrimerization Axonogenesis Glomerular Basement Membrane Development Blood Coagulation, Intrinsic Pathway Regulation Of Blood Coagulation Response To External Stimulus Axon Development Response To Amino Acid Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Renal System Development Regulation Of Wound Healing Neuron Projection Morphogenesis Response To Stimulus Negative Regulation Of Proteolysis Endocytosis Receptor-mediated Endocytosis Negative Regulation Of Growth Of Symbiont In Host Negative Regulation Of Protein Processing Establishment Of Endothelial Barrier Urogenital System Development Cell Morphogenesis Involved In Differentiation Immune System Process Protein Trimerization Cellular Response To Acid Chemical Blood Coagulation Inflammatory Response Hemostasis Immunoglobulin Mediated Immune Response B Cell Mediated Immunity Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Platelet Activation Neuron Projection Development Cell Projection Morphogenesis
Tagcloud ?			29a 29b 29c acp5 calcitonin calcr cdc42 commitment concert cytoskeletal gpr85 gtpase hypothesize mir monocytic multinucleated nfia osteoclast osteoclastic osteoclasts raw264 rnas robo slit sponge srgap2 tartrate tempo transduced
Tagcloud (Difference) ?			29a 29b 29c acp5 calcitonin calcr cdc42 commitment concert cytoskeletal gpr85 gtpase hypothesize mir monocytic multinucleated nfia osteoclast osteoclastic osteoclasts raw264 rnas robo slit sponge srgap2 tartrate tempo transduced
Tagcloud (Intersection) ?