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ARHGAP15
Description
Rho GTPase activating protein 15
Image
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Cytosol
Plasma Membrane
Membrane
Molecular Function
GTPase Activator Activity
Protein Binding
Biological Process
Signal Transduction
Small GTPase-mediated Signal Transduction
Regulation Of Cell Shape
Regulation Of Small GTPase Mediated Signal Transduction
Pathways
RAC1 GTPase cycle
RAC3 GTPase cycle
Drugs
Diseases
GWAS
Adult body size (
32376654
)
Age at first sexual intercourse (
34211149
)
Alcohol consumption (
31358974
)
Alcohol consumption (drinks per week) (
30643258
30679032
)
Allergic disease (asthma, hay fever or eczema) (
29083406
)
Appendicular lean mass (
33097823
)
Bitter alcoholic beverage consumption (
31046077
)
Chin dimples (
27182965
)
Chronotype (
30696823
)
Coronary artery disease (
29212778
33020668
)
Diastolic blood pressure (
30224653
)
Diisocyanate-induced asthma (
25918132
)
Diverticular disease (
28585551
30661054
30177863
)
Diverticulitis (
28585551
)
Electrodermal activity (
25387706
)
Eosinophil count (
32888494
)
Experiencing mood swings (
29500382
)
Extremely high intelligence (
29520040
)
Femur bone mineral density x serum urate levels interaction (
34046847
)
Fish- and plant-related diet (
32066663
)
Fruit consumption (
32066663
)
Heel bone mineral density (
30598549
)
Hematocrit (
32888494
)
Hemoglobin (
32888494
)
Household income (MTAG) (
31844048
)
Intelligence (
28530673
)
Lymphocyte count (
32888494
27863252
)
Lymphocyte percentage of white cells (
32888494
)
Mean platelet volume (
32888494
)
Medication use (agents acting on the renin-angiotensin system) (
31015401
)
Metabolite levels (
23823483
)
Monocyte count (
32888494
)
Mood instability (
31168069
)
Morning person (
30696823
)
Myocardial infarction (
33532862
)
Neutrophil percentage of white cells (
32888494
)
Platelet distribution width (
32888494
)
Quantitative traits (
19197348
)
Response to SSRI (symptom remission) (
29160301
)
Smooth-surface caries (
24556642
)
Systemic lupus erythematosus (
33536424
)
TNF-alpha gene expression levels in non-alcoholic fatty liver disease x mastiha supplementation interaction (
34025683
)
Toenail selenium levels (
25343990
)
Tooth agenesis (
29364747
)
Vascular brain injury (
25188341
)
Walking pace (
33128006
)
White blood cell count (
27863252
32888494
)
Interacting Genes
9 interacting genes:
APP
CD93
CEBPA
KDM1A
PRNP
RAC1
SMURF1
SNCA
TGFBR1
Entrez ID
55843
HPRD ID
06447
Ensembl ID
ENSG00000075884
Uniprot IDs
Q53QZ3
PDB IDs
3BYI
Enriched GO Terms of Interacting Partners
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Regulation Of Protein Metabolic Process
Regulation Of Plasma Membrane Bounded Cell Projection Organization
Regulation Of Cell Projection Organization
Cellular Response To Copper Ion
Response To Copper Ion
Cellular Response To Metal Ion
Regulation Of Synaptic Plasticity
Regulation Of Neuronal Synaptic Plasticity
Postsynapse
Macrophage Activation
Positive Regulation Of Cellular Component Organization
Regulation Of Multicellular Organismal Process
Cuprous Ion Binding
Regulation Of Stem Cell Proliferation
Regulation Of Synapse Organization
Response To Metal Ion
Negative Regulation Of Long-term Synaptic Potentiation
Positive Regulation Of Developmental Process
Neuron Projection Maintenance
Regulation Of Dendritic Spine Maintenance
Positive Regulation Of Protein Metabolic Process
Regulation Of Proteolysis
Regulation Of Supramolecular Fiber Organization
Negative Regulation Of Signaling
Negative Regulation Of Signal Transduction
Intracellular Copper Ion Homeostasis
Memory
Negative Regulation Of Cell Communication
Regulation Of Hydrogen Peroxide Metabolic Process
Positive Regulation Of Cell Projection Organization
I-SMAD Binding
Regulation Of Cellular Component Organization
Regulation Of Cell Differentiation
Enzyme Binding
Positive Regulation Of Cell Differentiation
Myeloid Leukocyte Activation
Regulation Of Reactive Oxygen Species Metabolic Process
Copper Ion Homeostasis
Inclusion Body
Regulation Of Protein Localization
Regulation Of Postsynapse Organization
Regulation Of Neurotransmitter Uptake
Positive Regulation Of Protein Localization
Regulation Of Calcium Ion Transmembrane Transport
Endocytosis
Cell Maturation
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Synapse Assembly
Regulation Of Presynapse Organization
Positive Regulation Of Inflammatory Response
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