PRKCH and PPP1R14A

Number of citations of the paper that reports this interaction (PMID 15003508)
6

Data Source:
BioGRID (pull down)

		PRKCH	PPP1R14A
Gene Name		protein kinase C, eta	protein phosphatase 1, regulatory (inhibitor) subunit 14A
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Extracellular Vesicular Exosome	Cytoplasm
	Molecular Function	Protein Kinase C Activity Calcium-independent Protein Kinase C Activity ATP Binding Ral GTPase Binding Enzyme Binding Metal Ion Binding	Protein Phosphatase Inhibitor Activity
	Biological Process	Protein Phosphorylation Signal Transduction Blood Coagulation Positive Regulation Of Macrophage Derived Foam Cell Differentiation Platelet Activation Negative Regulation Of Glial Cell Apoptotic Process Positive Regulation Of Keratinocyte Differentiation Positive Regulation Of B Cell Receptor Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Glial Cell Proliferation Protein Kinase C Signaling Regulation Of Tight Junction Assembly	Regulation Of Phosphorylation Negative Regulation Of Catalytic Activity
Pathways		G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Gastrin-CREB signalling pathway via PKC and MAPK G alpha (z) signalling events Platelet activation, signaling and aggregation Effects of PIP2 hydrolysis
Drugs
Diseases
GWAS		Obesity (early onset extreme) ( 23563609) Reading and spelling ( 23738518) Rheumatoid arthritis ( 22446963) Word reading ( 23738518)
Protein-Protein Interactions		13 interactors: BANP CDK2 FYN GSK3A ITGB2 NFE2L2 NUMB PARD6A PPP1R14A PRKD1 PTPN11 SRC ZBTB8OS	15 interactors: APP CSNK1A1 CSNK1D CSNK1E CSNK1G1 CSNK1G2 CSNK1G3 PRKCA PRKCE PRKCG PRKCH PRKCZ PRKD1 PRNP YWHAZ
Entrez ID		5583	94274
HPRD ID		05669	16291
Ensembl ID		ENSG00000027075	ENSG00000167641
Uniprot IDs		P24723	Q96A00
PDB IDs		2FK9 3TXO
Enriched GO Terms of Interacting Partners?		Cellular Response To Growth Factor Stimulus Response To Growth Factor Integrin-mediated Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Blood Coagulation Innate Immune Response Hemostasis Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Immune Response-regulating Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Protein Metabolic Process Neurotrophin TRK Receptor Signaling Pathway Leukocyte Migration Neurotrophin Signaling Pathway T Cell Costimulation Regulation Of Body Fluid Levels Chemotaxis Fc Receptor Signaling Pathway Wound Healing Regulation Of Cellular Response To Insulin Stimulus Cellular Response To Platelet-derived Growth Factor Stimulus Cellular Response To Peptide Hormone Stimulus Response To Platelet-derived Growth Factor Negative Regulation Of Signaling Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Ephrin Receptor Signaling Pathway Cellular Response To Peptide Cellular Response To Organic Substance Vascular Endothelial Growth Factor Receptor Signaling Pathway Response To Wounding Activated T Cell Proliferation Cell Proliferation Locomotion Immune Response Regulation Of Phosphorylation Defense Response Immune Response-regulating Cell Surface Receptor Signaling Pathway Signal Transduction Axon Guidance Cell Migration Phosphatidylinositol-mediated Signaling Response To Oxidative Stress Cell Surface Receptor Signaling Pathway Regulation Of Immune Response Movement Of Cell Or Subcellular Component Regulation Of Phosphorus Metabolic Process Cell Motility	Peptidyl-serine Phosphorylation Protein Phosphorylation Phosphorylation Phosphate-containing Compound Metabolic Process Platelet Activation Peptidyl-amino Acid Modification Positive Regulation Of Signal Transduction Cellular Protein Modification Process Regulation Of Cell Shape Regulation Of Cellular Component Organization Vesicle-mediated Transport Endocytosis Regulation Of Signal Transduction Blood Coagulation Hemostasis Cellular Response To Stimulus Regulation Of Signaling Signal Transduction Cell Surface Receptor Signaling Pathway Wnt Signaling Pathway Cellular Protein Metabolic Process Signaling Regulation Of Body Fluid Levels Cell Communication Wound Healing Cell Activation Positive Regulation Of Phospholipase Activity Response To Wounding Response To Stimulus Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Regulation Of Cell Morphogenesis Protein Metabolic Process Response To Stress Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Cell Death Regulation Of Protein Metabolic Process Regulation Of Protein Phosphorylation Positive Regulation Of Wnt Signaling Pathway Regulation Of Cellular Amino Acid Metabolic Process Activation Of Phospholipase C Activity Single-organism Behavior Positive Regulation Of Phospholipase C Activity Regulation Of Phosphorylation Defense Response Regulation Of Peptidyl-tyrosine Phosphorylation Protein Autophosphorylation Regulation Of Canonical Wnt Signaling Pathway Regulation Of Cellular Ketone Metabolic Process
Tagcloud ?		adjust adora2a avp cart cecal clp gng7 intramuscular ku myh7 oxt pde1b pdyn preconditioning prkcd puncture ratref reproduced rgs9 rxrg s100a8 sepsis six3 slc17a6 slco1a5 sostdc1 tac1 ttr ulinastatin
Tagcloud (Difference) ?		adjust adora2a avp cart cecal clp gng7 intramuscular ku myh7 oxt pde1b pdyn preconditioning prkcd puncture ratref reproduced rgs9 rxrg s100a8 sepsis six3 slc17a6 slco1a5 sostdc1 tac1 ttr ulinastatin
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