PRKCH and ZBTB8OS

Number of citations of the paper that reports this interaction (PubMedID 20936779)
36

Data Source:
BioGRID (two hybrid)

		PRKCH	ZBTB8OS
Description		protein kinase C eta	zinc finger and BTB domain containing 8 opposite strand
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm TRNA-splicing Ligase Complex
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Diacylglycerol-dependent Serine/threonine Kinase Activity Diacylglycerol-dependent, Calcium-independent Serine/threonine Kinase Activity Protein Kinase Inhibitor Activity Protein Binding ATP Binding Zinc Ion Binding Kinase Activity Transferase Activity Enzyme Binding Protein Serine/threonine Kinase Inhibitor Activity Small GTPase Binding Translation Regulator Activity Metal Ion Binding Protein Serine Kinase Activity Protein Serine/threonine Kinase Binding	Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Translation Protein Phosphorylation Signal Transduction Positive Regulation Of Macrophage Derived Foam Cell Differentiation Negative Regulation Of Translation Cell Differentiation Positive Regulation Of Translation In Response To Stress Cellular Response To Amino Acid Starvation Negative Regulation Of Glial Cell Apoptotic Process Intracellular Signal Transduction Positive Regulation Of Keratinocyte Differentiation Positive Regulation Of B Cell Receptor Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Glial Cell Proliferation Phospholipase C/protein Kinase C Signal Transduction Positive Regulation Of Protein Localization To Plasma Membrane Regulation Of Bicellular Tight Junction Assembly	TRNA Splicing, Via Endonucleolytic Cleavage And Ligation TRNA Processing
Pathways		Effects of PIP2 hydrolysis G alpha (z) signalling events	tRNA processing in the nucleus
Drugs
Diseases
GWAS		Asthma ( 32296059) Height ( 28552196) Obesity (early onset extreme) ( 23563609) Reading and spelling ( 23738518) Rheumatoid arthritis ( 22446963 24390342 30423114) Word reading ( 23738518) Yeast infection ( 28928442)
Interacting Genes		12 interacting genes: BANP CDK2 FYN GSK3A ITGB2 NUMB PARD6A PPP1R14A PRKD1 PTPN11 SRC ZBTB8OS	2 interacting genes: GPANK1 PRKCH
Entrez ID		5583	339487
HPRD ID		05669	12470
Ensembl ID		ENSG00000027075	ENSG00000176261
Uniprot IDs		P24723	A0A8C8MQ05 A8K0B5 D3DPQ2 Q8IWT0
PDB IDs		2FK9 3TXO 8FP1 8FP3	5YZ1 5YZJ 5YZL 8BTX 8ODO 8ODP
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Localization Regulation Of Protein Localization Cellular Response To Growth Factor Stimulus Regulation Of Establishment Of Protein Localization Response To Growth Factor Forebrain Development Cellular Response To Peptide Hormone Stimulus Positive Regulation Of Protein Localization To Nucleus Integrin-mediated Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Transport Positive Regulation Of Multicellular Organismal Process Response To Peptide Hormone Positive Regulation Of Establishment Of Protein Localization T Cell Costimulation Regulation Of Protein Localization To Nucleus Cellular Response To Hormone Stimulus Ephrin Receptor Signaling Pathway Negative Regulation Of Neutrophil Activation Enzyme-linked Receptor Protein Signaling Pathway Regulation Of Multicellular Organismal Development Regulation Of Leukocyte Cell-cell Adhesion Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Phospholipase Activator Activity Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Peptide Hormone Receptor Binding Regulation Of Neutrophil Activation Positive Regulation Of Protein Localization BMP Receptor Binding Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Neutrophil Activation Involved In Immune Response Cellular Response To Steroid Hormone Stimulus Regulation Of Cell Adhesion Regulation Of Striated Muscle Cell Differentiation Protein Kinase Activity Positive Regulation Of Cell Adhesion Regulation Of Cell-cell Adhesion Regulation Of Lymphocyte Activation Regulation Of Intracellular Transport Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Cellular Response To Chemical Stress Negative Regulation Of Cell Cycle Process Cellular Response To Oxygen-containing Compound Positive Regulation Of Leukocyte Cell-cell Adhesion Cell Differentiation Regulation Of Developmental Process Leukocyte Activation Tau-protein Kinase Activity Stimulatory C-type Lectin Receptor Signaling Pathway	Regulation Of Bicellular Tight Junction Assembly Positive Regulation Of Macrophage Derived Foam Cell Differentiation Phospholipase C/protein Kinase C Signal Transduction Positive Regulation Of Antigen Receptor-mediated Signaling Pathway Positive Regulation Of Glial Cell Proliferation Regulation Of B Cell Receptor Signaling Pathway Translation Regulator Activity Negative Regulation Of Glial Cell Apoptotic Process Regulation Of Translation In Response To Stress Positive Regulation Of B Cell Receptor Signaling Pathway Positive Regulation Of Keratinocyte Differentiation Positive Regulation Of Epidermal Cell Differentiation Diacylglycerol-dependent Serine/threonine Kinase Activity Diacylglycerol-dependent, Calcium-independent Serine/threonine Kinase Activity Positive Regulation Of Translation In Response To Stress Protein Serine/threonine Kinase Inhibitor Activity Protein Serine/threonine Kinase Binding Positive Regulation Of Epidermis Development Regulation Of Macrophage Derived Foam Cell Differentiation Regulation Of Keratinocyte Differentiation Regulation Of Glial Cell Proliferation Protein Kinase Inhibitor Activity Cellular Response To Amino Acid Starvation Positive Regulation Of Epithelial Cell Differentiation Regulation Of Epidermal Cell Differentiation Response To Amino Acid Starvation Positive Regulation Of Gliogenesis Regulation Of Epidermis Development Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Cell Periphery Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Protein Localization To Membrane
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