UTP6 and TRAK1

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		UTP6	TRAK1
Description		UTP6 small subunit processome component	trafficking kinesin protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Nucleolus Small-subunit Processome Pwp2p-containing Subcomplex Of 90S Preribosome	Nucleus Cytoplasm Mitochondrion Endosome Early Endosome Cytosol Cell Cortex Membrane Dendrite Cytoplasmic Vesicle Mitochondrial Membrane Axonal Growth Cone Perinuclear Region Of Cytoplasm Axon Cytoplasm
	Molecular Function	Protein Binding SnoRNA Binding	Protein Binding Myosin Binding TPR Domain Binding GABA Receptor Binding
	Biological Process	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing RNA Processing Ribosomal Small Subunit Biogenesis	Regulation Of Transcription By RNA Polymerase II Protein O-linked Glycosylation Protein Targeting Endosome To Lysosome Transport Axonal Transport Of Mitochondrion Neurogenesis Vesicle Transport Along Microtubule Mitochondrion Distribution Dendrite Morphogenesis Positive Regulation Of Axonogenesis
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol	Signaling by BRAF and RAF1 fusions RHOT2 GTPase cycle RHOT1 GTPase cycle
Drugs
Diseases
GWAS		High chromosomal aberration frequency (chromosome type) in genotoxic compound exposure ( 31586183)	Body mass index ( 28552196) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) PR interval ( 32439900) Pulse pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Pulse pressure x alcohol consumption interaction (2df test) ( 29912962) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Interacting Genes		8 interacting genes: CCDC85B ESS2 KXD1 QKI RHOXF2 TFIP11 TRAK1 TSNAXIP1	17 interacting genes: BLOC1S6 BYSL CDC5L CDK6 ENKD1 ESS2 HGS MAGEB4 OGT POLR2A PRPF6 PTBP1 SKIL SNW1 TRAF3IP1 UTP6 ZNF232
Entrez ID		55813	22906
HPRD ID		11020	09732
Ensembl ID		ENSG00000108651	ENSG00000182606
Uniprot IDs		Q9NYH9	A0A087X0N0 A0A0D9SFL5 B7Z218 B7ZAE5 C9JC32 Q9UPV9
PDB IDs		7MQ8 7MQ9 7MQA
Enriched GO Terms of Interacting Partners?		MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing Catalytic Step 2 Spliceosome Myofibroblast Contraction Internal N(7)-methylguanine-containing RNA Reader Activity Negative Regulation Of MiRNA Catabolic Process Organelle Transport Along Microtubule Spliceosomal Complex Disassembly Developmental Process U2-type Post-mRNA Release Spliceosomal Complex	Catalytic Step 2 Spliceosome RNA Processing RNA Metabolic Process Spliceosomal Complex RNA Splicing MRNA Metabolic Process Nucleoplasm MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Processing Prp19 Complex Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) SnoRNA Binding Blastocyst Formation Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process Dentate Gyrus Development Regulation Of Cellular Response To Growth Factor Stimulus U2-type Catalytic Step 2 Spliceosome Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Organelle Assembly Maturation Of SSU-rRNA Regulation Of RNA Splicing Positive Regulation Of RNA Splicing Ciliary Base Regulation Of Nucleobase-containing Compound Metabolic Process Cyclin D2-CDK6 Complex Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Bradykinin Biosynthetic Process Circadian Sleep/wake Cycle SMAD Binding Nucleus Regulation Of Macromolecule Metabolic Process Protein Domain Specific Binding Protein Localization To Lysosome Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Developmental Process Negative Regulation Of Transcription By RNA Polymerase II Cyclin D3-CDK6 Complex Cyclin D1-CDK6 Complex FBXO Family Protein Binding
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