UTP6 and ESS2

Number of citations: 84 (PubMedID 34133714)
Data Source: BioGRID (two hybrid)

		UTP6	ESS2
Name		UTP6 small subunit processome component	ess-2 spliceosome associated protein
Structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Nucleolus Small-subunit Processome Pwp2p-containing Subcomplex Of 90S Preribosome	Nucleus Spliceosomal Complex Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding SnoRNA Binding	Protein Binding
	Biological Process	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing RNA Processing Ribosomal Small Subunit Biogenesis	MRNA Splicing, Via Spliceosome MRNA Processing Nervous System Development RNA Splicing
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol	None
GWAS		High chromosomal aberration frequency (chromosome type) in genotoxic compound exposure ( 31586183 )	No GWAS studies recorded
Interacting Genes		8 interacting genes: CCDC85B ESS2 KXD1 QKI RHOXF2 TFIP11 TRAK1 TSNAXIP1	33 interacting genes: ARMC7 CCDC57 CDK5RAP3 CEP55 CPSF7 CRP DGCR6 DHX16 EHMT2 EXOC8 EXOSC7 HOOK1 ITCH KRT31 LYST NEDD4 OGT OIP5 PFDN1 PRPF38B PRRC2B QARS1 RACK1 RBM22 RBM4 SMARCD1 THOC1 TRAK1 TTC14 UTP6 VIM WNK2 YAP1
Entrez ID		55813	8220
HPRD ID		11020	03452
Ensembl ID		ENSG00000108651	ENSG00000100056
Uniprot IDs		Q9NYH9	F8WEF8 Q96DF8
PDB IDs		7MQ8 7MQ9 7MQA	8C6J 8RO2 9FMD
GO Terms Enriched among Interactors		MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing Catalytic Step 2 Spliceosome Myofibroblast Contraction Internal N(7)-methylguanine-containing RNA Reader Activity Negative Regulation Of MiRNA Catabolic Process Organelle Transport Along Microtubule Spliceosomal Complex Disassembly Developmental Process U2-type Post-mRNA Release Spliceosomal Complex	RNA Metabolic Process Cyclin Binding RNA Processing MRNA Metabolic Process MRNA Processing RNA Splicing Lysosomal Transport Positive Regulation Of Stem Cell Population Maintenance Endosome To Lysosome Transport Vacuolar Transport Negative Regulation Of MAPK Cascade RNA Binding Regulation Of Stem Cell Population Maintenance Spliceosomal Complex Molecular Adaptor Activity Proline-rich Region Binding Regulation Of Macroautophagy Pre-mRNA Binding