TBC1D23 and EHD2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		TBC1D23	EHD2
Gene Name		TBC1 domain family, member 23	EH-domain containing 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Plasma Membrane Caveola Endosome Membrane Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Rab GTPase Activator Activity	Nucleic Acid Binding Calcium Ion Binding Protein Binding ATP Binding GTP Binding Hydrolase Activity Protein Domain Specific Binding
	Biological Process	Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Rab GTPase Activity Regulation Of Inflammatory Response	Endocytosis Blood Coagulation Metabolic Process Cortical Actin Cytoskeleton Organization Endocytic Recycling Protein Localization To Plasma Membrane Positive Regulation Of Myoblast Fusion Positive Regulation Of Endocytic Recycling
Pathways			Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Protein-Protein Interactions		9 interactors: C12orf45 CAGE1 EHD2 KRTAP10-3 KRTAP10-8 KRTAP10-9 KRTAP4-12 SSBP3 WDR62	13 interactors: AP1M1 AP1M2 AP2M1 BPGM DDX56 EHBP1 PICALM PICK1 RBSN SLC2A4 SPATA24 TAGLN2 TBC1D23
Entrez ID		55773	30846
HPRD ID		07727	10434
Ensembl ID		ENSG00000036054	ENSG00000024422
Uniprot IDs		Q9NUY8	Q9NZN4
PDB IDs
Enriched GO Terms of Interacting Partners?		Prechordal Plate Formation Midbrain-hindbrain Boundary Initiation Positive Regulation Of Anterior Head Development Neural Plate Anterior/posterior Regionalization Positive Regulation Of Endocytic Recycling Regulation Of Cardiac Muscle Cell Membrane Potential Regulation Of Endocytic Recycling Midbrain-hindbrain Boundary Development Positive Regulation Of Myoblast Fusion Rostrocaudal Neural Tube Patterning Regulation Of Myoblast Fusion Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion Endocytic Recycling Brain Development Cortical Actin Cytoskeleton Organization Head Development Cortical Cytoskeleton Organization Positive Regulation Of Myotube Differentiation Central Nervous System Development Protein Targeting To Plasma Membrane Head Morphogenesis Protein Complex Assembly Regulation Of Myotube Differentiation Body Morphogenesis Neural Tube Patterning Positive Regulation Of Striated Muscle Cell Differentiation Establishment Of Protein Localization To Plasma Membrane	Regulation Of Defense Response To Virus By Virus Membrane Organization Regulation Of Defense Response To Virus Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Cell Differentiation Clathrin-mediated Endocytosis Antigen Processing And Presentation Of Peptide Antigen Golgi Vesicle Transport Vesicle-mediated Transport Antigen Processing And Presentation Intracellular Transport Amylopectin Biosynthetic Process Positive Regulation Of Aspartic-type Endopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process Intracellular Protein Transport Developmental Process Post-Golgi Vesicle-mediated Transport Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Establishment Of Localization In Cell Viral Process Immune System Process Regulation Of Aspartic-type Endopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process Negative Regulation Of Metalloendopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process Synaptic Transmission Cellular Protein Localization Cargo Loading Into Vesicle Protein Transport Cellular Localization Iron Ion Import Into Cell Establishment Of Protein Localization Regulation Of Endocytosis DNA Methylation Involved In Embryo Development Establishment Of Vesicle Localization Vesicle Organization Pigment Granule Maturation Endosome To Melanosome Transport Glucose Import Endosomal Transport Vesicle Localization Dendritic Spine Maintenance Cellular Pigment Accumulation Synaptic Vesicle Maturation Positive Regulation Of Beta-amyloid Formation Neuronal Ion Channel Clustering Negative Regulation Of Amyloid Precursor Protein Catabolic Process Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Iron Ion Import Negative Regulation Of Actin Nucleation
Tagcloud ?			acted adapter converts cytoplasm cytoskeleton deprived deregulated direction e2 enrichment fhl2 homer3 hydroxytamoxifen mcf modulator oestrogen oht organelle overlap pf rationale remarkable remodelling reorganisation reprogrammed rhof transcriptome uncovered unexpectedly
Tagcloud (Difference) ?			acted adapter converts cytoplasm cytoskeleton deprived deregulated direction e2 enrichment fhl2 homer3 hydroxytamoxifen mcf modulator oestrogen oht organelle overlap pf rationale remarkable remodelling reorganisation reprogrammed rhof transcriptome uncovered unexpectedly
Tagcloud (Intersection) ?