SNX4 and ATP6V0A1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		SNX4	ATP6V0A1
Gene Name		sorting nexin 4	ATPase, H+ transporting, lysosomal V0 subunit a1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoplasmic Dynein Complex Plasma Membrane Membrane Extrinsic Component Of Membrane SNARE Complex Early Endosome Membrane Protein Complex	Vacuolar Proton-transporting V-type ATPase, V0 Domain Nucleoplasm Cytoplasm Golgi Apparatus Plasma Membrane Endosome Membrane Integral Component Of Membrane Vacuolar Proton-transporting V-type ATPase Complex Phagocytic Vesicle Membrane Melanosome Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome
	Molecular Function	Epidermal Growth Factor Receptor Binding Insulin Receptor Binding Protein Binding Phosphatidylinositol Binding Transferrin Receptor Binding Leptin Receptor Binding	Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism ATPase Binding
	Biological Process	Protein Transport Vesicle Organization Endocytic Recycling Positive Regulation Of Histamine Secretion By Mast Cell	Cellular Iron Ion Homeostasis Vacuolar Acidification Insulin Receptor Signaling Pathway ATP Synthesis Coupled Proton Transport ATP Hydrolysis Coupled Proton Transport Transferrin Transport Interaction With Host Transmembrane Transport Vacuolar Proton-transporting V-type ATPase Complex Assembly Phagosome Maturation
Pathways			Phagosomal maturation (early endosomal stage) Iron uptake and transport Latent infection of Homo sapiens with Mycobacterium tuberculosis Transferrin endocytosis and recycling Insulin receptor recycling Signaling by Insulin receptor
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: AGK ARL6IP1 ATP6V0A1 BIN1 EGFR HIVEP1 INSR LEPR MAGEA6 PDGFRA PDGFRB PTPN5 SNX2 SNX6 SUPT5H	4 interactors: CLIC1 SEH1L SNX4 ZNF267
Entrez ID		8723	535
HPRD ID		09334	01886
Ensembl ID		ENSG00000114520	ENSG00000033627
Uniprot IDs		O95219	B7Z2A9 B7Z641 Q53ET5 Q53X12 Q5CZH6 Q93050
PDB IDs
Enriched GO Terms of Interacting Partners?		Metanephric Glomerular Capillary Formation Positive Regulation Of Cell Proliferation By VEGF-activated Platelet Derived Growth Factor Receptor Signaling Pathway Positive Regulation Of DNA Metabolic Process Positive Regulation Of Phospholipase C Activity Glomerular Capillary Formation Protein Autophosphorylation Positive Regulation Of DNA Replication Metanephric Glomerulus Vasculature Development Positive Regulation Of Phospholipase Activity Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Peptidyl-tyrosine Phosphorylation Metanephric Glomerulus Development Glomerulus Morphogenesis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Regulation Of DNA Replication Positive Regulation Of ERK1 And ERK2 Cascade Retina Vasculature Development In Camera-type Eye Glomerulus Vasculature Development Cardiac Myofibril Assembly Cellular Response To Platelet-derived Growth Factor Stimulus Phosphatidylinositol-mediated Signaling Response To Platelet-derived Growth Factor Regulation Of Kinase Activity Digestive System Development Regulation Of Reactive Oxygen Species Metabolic Process Vascular Endothelial Growth Factor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of MAPK Cascade ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Phosphatidylinositol 3-kinase Activity Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Organonitrogen Compound Positive Regulation Of Kinase Activity Regulation Of Cellular Ketone Metabolic Process Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of ERK1 And ERK2 Cascade Response To Fibroblast Growth Factor Adrenal Gland Development Metanephric Nephron Development Regulation Of Peptidyl-tyrosine Phosphorylation Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of MAP Kinase Activity Regulation Of Catalytic Activity	Positive Regulation Of Histamine Secretion By Mast Cell Regulation Of Histamine Secretion By Mast Cell Attachment Of Mitotic Spindle Microtubules To Kinetochore Cytokine Production Involved In Inflammatory Response Nuclear Pore Organization Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Mast Cell Degranulation Positive Regulation Of Mast Cell Activation Positive Regulation Of Regulated Secretory Pathway Endocytic Recycling Regulation Of Ion Transport Regulation Of Mast Cell Degranulation Production Of Molecular Mediator Involved In Inflammatory Response Mitotic Metaphase Plate Congression Metaphase Plate Congression Regulation Of Mitochondrial Membrane Potential Mitotic Nuclear Envelope Disassembly Regulation Of Mast Cell Activation Platelet Aggregation Regulation Of Regulated Secretory Pathway Nuclear Envelope Disassembly Establishment Of Chromosome Localization
Tagcloud ?			acidification atpase autophagosomes betaa1 betaa3 cko coimmunoprecipitates cryba1 crystallin ctsd droplets electroretinography endolysosomal fundus helping knocked phagocytic phagocytosis photographs photoreceptor pigment pmtor raptor rpe rptor scattered undigested vacuole
Tagcloud (Difference) ?			acidification atpase autophagosomes betaa1 betaa3 cko coimmunoprecipitates cryba1 crystallin ctsd droplets electroretinography endolysosomal fundus helping knocked phagocytic phagocytosis photographs photoreceptor pigment pmtor raptor rpe rptor scattered undigested vacuole
Tagcloud (Intersection) ?