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PARVA and MOCOS
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
PARVA
MOCOS
Gene Name
parvin, alpha
molybdenum cofactor sulfurase
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Plasma Membrane
Focal Adhesion
Actin Cytoskeleton
Z Disc
Lamellipodium
Cellular_component
Cytosol
Molecular Function
Actin Binding
Protein Binding
Mo-molybdopterin Cofactor Sulfurase Activity
Transferase Activity
Lyase Activity
Molybdenum Ion Binding
Pyridoxal Phosphate Binding
Biological Process
Sprouting Angiogenesis
Outflow Tract Septum Morphogenesis
Establishment Or Maintenance Of Cell Polarity
Regulation Of Cell Shape
Actin Cytoskeleton Reorganization
Heterotypic Cell-cell Adhesion
Cell Junction Assembly
Substrate Adhesion-dependent Cell Spreading
Cilium Morphogenesis
Actin-mediated Cell Contraction
Smooth Muscle Cell Chemotaxis
Vitamin Metabolic Process
Water-soluble Vitamin Metabolic Process
Mo-molybdopterin Cofactor Biosynthetic Process
Molybdopterin Cofactor Biosynthetic Process
Molybdopterin Cofactor Metabolic Process
Small Molecule Metabolic Process
Pathways
Cell junction organization
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
Localization of the PINCH-ILK-PARVIN complex to focal adhesions
Cell-extracellular matrix interactions
Metabolism of vitamins and cofactors
Defective CD320 causes methylmalonic aciduria
Defective GIF causes intrinsic factor deficiency
Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF
Defective HLCS causes multiple carboxylase deficiency
Defective MMAB causes methylmalonic aciduria type cblB
Defective BTD causes biotidinase deficiency
Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC
Defective MTR causes methylmalonic aciduria and homocystinuria type cblG
Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD
Defective MMAA causes methylmalonic aciduria type cblA
Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE
Defective CUBN causes hereditary megaloblastic anemia 1
Molybdenum cofactor biosynthesis
Defective AMN causes hereditary megaloblastic anemia 1
Defective MUT causes methylmalonic aciduria mut type
Metabolism of water-soluble vitamins and cofactors
Defects in biotin (Btn) metabolism
Defective TCN2 causes hereditary megaloblastic anemia
Defects in vitamin and cofactor metabolism
Defects in cobalamin (B12) metabolism
Drugs
Diseases
GWAS
Mortality among heart failure patients (
20400778
)
Protein-Protein Interactions
10 interactors:
ACTA1
APP
ILK
LIMS1
MAP2K1
MLH1
MOCOS
PXN
UBC
UBE3A
1 interactors:
PARVA
Entrez ID
55742
55034
HPRD ID
16283
17585
Ensembl ID
Uniprot IDs
J3KNQ4
Q9NVD7
Q96EN8
PDB IDs
2K2R
2VZC
2VZD
2VZG
2VZI
3KMU
3KMW
3REP
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of MAP Kinase Activity
Cellular Component Assembly
Cell Aging
Positive Regulation Of Protein Serine/threonine Kinase Activity
Positive Regulation Of Signal Transduction
Regulation Of MAP Kinase Activity
Regulation Of Protein Kinase Activity
Regulation Of Kinase Activity
Positive Regulation Of Intracellular Signal Transduction
Positive Regulation Of Catalytic Activity
Positive Regulation Of Gene Expression
Protein Heterooligomerization
Positive Regulation Of MAPK Cascade
Activation Of MAPK Activity
Regulation Of Signal Transduction
Positive Regulation Of Protein Kinase Activity
Protein Complex Assembly
Cell Development
Positive Regulation Of Kinase Activity
Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of Protein Phosphorylation
ERBB Signaling Pathway
Cell-matrix Adhesion
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of Cellular Protein Metabolic Process
Regulation Of Signaling
Cellular Response To Transforming Growth Factor Beta Stimulus
Positive Regulation Of Transferase Activity
Response To Transforming Growth Factor Beta
Cellular Response To Growth Factor Stimulus
Cell Junction Assembly
Intracellular Receptor Signaling Pathway
Positive Regulation Of Protein Metabolic Process
Response To Growth Factor
Cellular Response To Stimulus
Cell-substrate Adhesion
Multicellular Organismal Development
Regulation Of MAPK Cascade
Regulation Of Protein Metabolic Process
Regulation Of Phosphorylation
Anatomical Structure Development
Positive Regulation Of Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Substrate Adhesion-dependent Cell Spreading
Regulation Of Catalytic Activity
Cell Morphogenesis Involved In Differentiation
Positive Regulation Of Protein Phosphorylation
Activation Of Protein Kinase Activity
Regulation Of Phosphorus Metabolic Process
Smooth Muscle Cell Chemotaxis
Outflow Tract Septum Morphogenesis
Heterotypic Cell-cell Adhesion
Smooth Muscle Cell Migration
Muscle Cell Migration
Substrate Adhesion-dependent Cell Spreading
Actin-mediated Cell Contraction
Sprouting Angiogenesis
Cardiac Septum Morphogenesis
Outflow Tract Morphogenesis
Actin Filament-based Movement
Actin Cytoskeleton Reorganization
Cardiac Septum Development
Cardiac Chamber Development
Regulation Of Cell Shape
Cell Chemotaxis
Establishment Or Maintenance Of Cell Polarity
Cell Junction Assembly
Cell-substrate Adhesion
Cilium Morphogenesis
Heart Morphogenesis
Angiogenesis
Tagcloud
?
apicomplexan
bite
borne
coast
deoxyhypusine
dhs
druggable
ecf
enormous
genera
guanyl
heterocyclic
hitherto
hypusine
infects
invade
malaria
muguga
orf
plasmodium
quinone
rosetta
saharan
schizonts
spacer
sporozoites
theileria
tick
transforms
Tagcloud (Difference)
?
apicomplexan
bite
borne
coast
deoxyhypusine
dhs
druggable
ecf
enormous
genera
guanyl
heterocyclic
hitherto
hypusine
infects
invade
malaria
muguga
orf
plasmodium
quinone
rosetta
saharan
schizonts
spacer
sporozoites
theileria
tick
transforms
Tagcloud (Intersection)
?