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MOCOS
Gene Name
molybdenum cofactor sulfurase
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cellular_component
Cytosol
Molecular Function
Mo-molybdopterin Cofactor Sulfurase Activity
Transferase Activity
Lyase Activity
Molybdenum Ion Binding
Pyridoxal Phosphate Binding
Biological Process
Vitamin Metabolic Process
Water-soluble Vitamin Metabolic Process
Mo-molybdopterin Cofactor Biosynthetic Process
Molybdopterin Cofactor Biosynthetic Process
Molybdopterin Cofactor Metabolic Process
Small Molecule Metabolic Process
Pathways
Metabolism of vitamins and cofactors
Defective CD320 causes methylmalonic aciduria
Defective GIF causes intrinsic factor deficiency
Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF
Defective HLCS causes multiple carboxylase deficiency
Defective MMAB causes methylmalonic aciduria type cblB
Defective BTD causes biotidinase deficiency
Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC
Defective MTR causes methylmalonic aciduria and homocystinuria type cblG
Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD
Defective MMAA causes methylmalonic aciduria type cblA
Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE
Defective CUBN causes hereditary megaloblastic anemia 1
Molybdenum cofactor biosynthesis
Defective AMN causes hereditary megaloblastic anemia 1
Defective MUT causes methylmalonic aciduria mut type
Metabolism of water-soluble vitamins and cofactors
Defects in biotin (Btn) metabolism
Defective TCN2 causes hereditary megaloblastic anemia
Defects in vitamin and cofactor metabolism
Defects in cobalamin (B12) metabolism
Drugs
Diseases
GWAS
Protein-protein Interactions
1 interactors:
PARVA
Entrez ID
55034
HPRD ID
17585
Ensembl ID
Uniprot IDs
Q96EN8
PDB IDs
Enriched GO Terms of Interacting Partners
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Smooth Muscle Cell Chemotaxis
Outflow Tract Septum Morphogenesis
Heterotypic Cell-cell Adhesion
Smooth Muscle Cell Migration
Muscle Cell Migration
Substrate Adhesion-dependent Cell Spreading
Actin-mediated Cell Contraction
Sprouting Angiogenesis
Cardiac Septum Morphogenesis
Outflow Tract Morphogenesis
Actin Filament-based Movement
Actin Cytoskeleton Reorganization
Cardiac Septum Development
Cardiac Chamber Development
Regulation Of Cell Shape
Cell Chemotaxis
Establishment Or Maintenance Of Cell Polarity
Cell Junction Assembly
Cell-substrate Adhesion
Cilium Morphogenesis
Heart Morphogenesis
Angiogenesis
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