RUFY2 and RAB33B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RUFY2	RAB33B
Description		RUN and FYVE domain containing 2	RAB33B, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endosome	Golgi Membrane Endosome Golgi Apparatus Golgi Lumen Membrane Phagophore Assembly Site Membrane Presynapse
	Molecular Function	Protein Binding Zinc Ion Binding SH3 Domain Binding Metal Ion Binding	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity
	Biological Process	Regulation Of Endocytosis	Autophagosome Assembly Regulation Of Cell Growth Intra-Golgi Vesicle-mediated Transport Autophagy Protein Transport Regulation Of Exocytosis Rab Protein Signal Transduction Protein Localization To Golgi Apparatus Protein Localization To Phagophore Assembly Site Skeletal System Morphogenesis Regulation Of Epithelial Cell Proliferation Regulation Of Golgi Organization Negative Regulation Of Constitutive Secretory Pathway Regulation Of Retrograde Vesicle-mediated Transport, Golgi To ER
Pathways			Intra-Golgi traffic TBC/RABGAPs RAB geranylgeranylation
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		7 interacting genes: BMX DSCAM DUSP23 EPHA3 RAB33A RAB33B SF3B3	11 interacting genes: ACVR1 ATG16L1 ATG16L2 CCDC136 GOLGA2 RABEP1 RABGEF1 RUFY2 SIAH1 TGFBR1 USP6
Entrez ID		55680	83452
HPRD ID		11526	05808
Ensembl ID		ENSG00000204130	ENSG00000172007
Uniprot IDs		Q5GIA6 Q8WXA3	A0A494C0Z5 Q9H082
PDB IDs			6Y09 6ZAY
Enriched GO Terms of Interacting Partners?		Rab Protein Signal Transduction Neuron Recognition Post-embryonic Retina Morphogenesis In Camera-type Eye Netrin Receptor Binding Fasciculation Of Motor Neuron Axon Autophagosome Organization Autophagosome Assembly Negative Regulation Of Constitutive Secretory Pathway Regulation Of Retrograde Vesicle-mediated Transport, Golgi To ER Protein Tyrosine Kinase Activity Cell Recognition Fasciculation Of Sensory Neuron Axon	Activin Receptor Complex Activin Receptor Activity, Type I Transforming Growth Factor Beta Receptor Activity, Type I Endosome Viral RNA Genome Replication Negative Stranded Viral RNA Replication Atg12-Atg5-Atg16 Complex Positive Regulation Of Cardiac Epithelial To Mesenchymal Transition Activin Binding Transmembrane Receptor Protein Serine/threonine Kinase Activity Regulation Of Endocytosis Regulation Of Receptor-mediated Endocytosis Pharyngeal System Development Viral Genome Replication Transforming Growth Factor Beta Binding Recycling Endosome Phagophore Assembly Site Membrane Regulation Of Postsynaptic Neurotransmitter Receptor Internalization Activin Receptor Signaling Pathway Ventricular Septum Morphogenesis Regulation Of Vesicle-mediated Transport Positive Regulation Of SMAD Protein Signal Transduction Protein Transport Growth Factor Binding SMAD Binding Endocardial Cushion Cell Fate Commitment Vacuole-isolation Membrane Contact Site Positive Regulation Of Epithelial To Mesenchymal Transition Establishment Of Protein Localization Organelle Assembly Reproductive Process Regulation Of SMAD Protein Signal Transduction Endocytic Vesicle Cardiac Septum Morphogenesis Early Endosome Regulation Of Receptor Internalization Positive Regulation Of Determination Of Dorsal Identity Vascular Endothelial Cell Proliferation Epicardium Morphogenesis Negative Regulation Of Kit Signaling Pathway Negative Regulation Of Mast Cell Cytokine Production Axo-dendritic Transport Autophagosome C-terminal Protein Lipidation Regulation Of Apoptotic Signaling Pathway Developmental Process Involved In Reproduction Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Proepicardium Development Angiogenesis Involved In Coronary Vascular Morphogenesis
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