RUFY2 and RAB33A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RUFY2	RAB33A
Description		RUN and FYVE domain containing 2	RAB33A, member RAS oncogene family
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endosome	Golgi Membrane Endosome Golgi Apparatus Plasma Membrane Membrane
	Molecular Function	Protein Binding Zinc Ion Binding SH3 Domain Binding Metal Ion Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Regulation Of Endocytosis	Autophagosome Assembly Antigen Processing And Presentation Rab Protein Signal Transduction
Pathways			TBC/RABGAPs RAB geranylgeranylation
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 34021172)	Bipolar disorder ( 31043756) Height ( 31562340)
Interacting Genes		7 interacting genes: BMX DSCAM DUSP23 EPHA3 RAB33A RAB33B SF3B3	15 interacting genes: ARL6IP1 ATG16L1 ATG16L2 CCDC136 KRT31 KRT34 LNX1 LRP2BP PSMF1 RABAC1 RTN3 RTN4 RUFY2 RUFY3 SIAH1
Entrez ID		55680	9363
HPRD ID		11526	02272
Ensembl ID		ENSG00000204130	ENSG00000134594
Uniprot IDs		Q5GIA6 Q8WXA3	Q14088
PDB IDs
Enriched GO Terms of Interacting Partners?		Rab Protein Signal Transduction Neuron Recognition Post-embryonic Retina Morphogenesis In Camera-type Eye Netrin Receptor Binding Fasciculation Of Motor Neuron Axon Autophagosome Organization Autophagosome Assembly Negative Regulation Of Constitutive Secretory Pathway Regulation Of Retrograde Vesicle-mediated Transport, Golgi To ER Protein Tyrosine Kinase Activity Cell Recognition Fasciculation Of Sensory Neuron Axon	Endoplasmic Reticulum Tubular Network Formation Endoplasmic Reticulum Tubular Network Membrane Organization Endoplasmic Reticulum Membrane Organization Endoplasmic Reticulum Tubular Network Organization Negative Stranded Viral RNA Replication Atg12-Atg5-Atg16 Complex Viral RNA Genome Replication Endoplasmic Reticulum Organization Endoplasmic Reticulum Tubular Network Phagophore Assembly Site Membrane Viral Genome Replication Negative Regulation Of Amyloid-beta Formation Negative Regulation Of Amyloid Precursor Protein Catabolic Process Organelle Organization GTPase Binding Supramolecular Fiber Organization Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Amyloid-beta Formation Negative Regulation Of Axonogenesis Vacuole-isolation Membrane Contact Site Negative Regulation Of Vasculogenesis Positive Regulation Of ERBB3 Signaling Pathway Cell Adhesion Involved In Sprouting Angiogenesis Structural Constituent Of Skin Epidermis Nervous System Development Positive Regulation Of Retrograde Axon Cargo Transport C-terminal Protein Lipidation Intermediate Filament Organization Cell Differentiation Regulation Of Amide Metabolic Process Regulation Of Axon Extension Autophagosome Regulation Of Developmental Growth Positive Regulation Of Protein Localization To Endoplasmic Reticulum Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Autophagosome Assembly Negative Regulation Of Developmental Growth Positive Regulation Of L-glutamate Import Across Plasma Membrane Negative Regulation Of Dendrite Extension Cell Migration Involved In Vasculogenesis Autophagosome Organization Regulation Of Endoplasmic Reticulum Tubular Network Organization Regulation Of Branching Morphogenesis Of A Nerve Intracellular Sphingolipid Homeostasis Central Nervous System Vasculogenesis Endoplasmic Reticulum Tubular Network Membrane Regulation Of Cell Growth Negative Regulation Of Neuron Projection Development
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