RAB33B and RABEP1

Number of citations of the paper that reports this interaction (PubMedID 11718716)
0

Data Source:
HPRD (in vitro, in vivo)

		RAB33B	RABEP1
Description		RAB33B, member RAS oncogene family	rabaptin, RAB GTPase binding effector protein 1
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GO Annotations	Cellular Component	Golgi Membrane Endosome Golgi Apparatus Golgi Lumen Membrane Phagophore Assembly Site Membrane Presynapse	Cytoplasm Endosome Early Endosome Cytosol Endocytic Vesicle Cytoplasmic Vesicle Early Endosome Membrane Protein-containing Complex Recycling Endosome Glutamatergic Synapse
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity	GTPase Activator Activity Protein Binding Growth Factor Activity Protein Domain Specific Binding Protein Homodimerization Activity
	Biological Process	Autophagosome Assembly Regulation Of Cell Growth Intra-Golgi Vesicle-mediated Transport Autophagy Protein Transport Regulation Of Exocytosis Rab Protein Signal Transduction Protein Localization To Golgi Apparatus Protein Localization To Phagophore Assembly Site Skeletal System Morphogenesis Regulation Of Epithelial Cell Proliferation Regulation Of Golgi Organization Negative Regulation Of Constitutive Secretory Pathway Regulation Of Retrograde Vesicle-mediated Transport, Golgi To ER	Golgi To Plasma Membrane Transport Endocytosis Apoptotic Process Signal Transduction Protein Transport Vesicle-mediated Transport Membrane Fusion Regulation Of Postsynaptic Neurotransmitter Receptor Internalization Protein Localization To Ciliary Membrane
Pathways		Intra-Golgi traffic TBC/RABGAPs RAB geranylgeranylation	TBC/RABGAPs
Drugs
Diseases
GWAS			Body mass index ( 25673413 28892062) Lymphocyte count ( 32888494) Mean platelet volume ( 32888494) Red blood cell density in sickle cell anemia ( 28552477) White blood cell count ( 27863252)
Interacting Genes		11 interacting genes: ACVR1 ATG16L1 ATG16L2 CCDC136 GOLGA2 RABEP1 RABGEF1 RUFY2 SIAH1 TGFBR1 USP6	60 interacting genes: ABI2 AIMP2 AP1G1 AP1G2 ATXN7 BARD1 CASP3 CCDC120 CCND1 CDC73 CDK18 CDKL3 CEP57 CFAP53 ELOA ESCO2 FAM50B FAM90A1 GAP43 GGA1 GGA2 GGA3 HUNK ITSN1 LENG1 MAT2B MCRS1 NRIP1 ODAD3 PELI2 PKP2 PRPF3 RAB1A RAB33B RAB4A RAB4B RAB5A RABGEF1 RGS17 RNF39 SMURF1 SNAPIN SNCA SNW1 SRPK2 STAR TNS4 TRAPPC2L TRIM26 TSC2 TSHZ2 UBC UBTFL1 USP2 UTP14C WASHC3 YWHAG ZNF438 ZNF512B ZNF774
Entrez ID		83452	9135
HPRD ID		05808	04684
Ensembl ID		ENSG00000172007	ENSG00000029725
Uniprot IDs		A0A494C0Z5 Q9H082	B4DMM4 Q15276
PDB IDs		6Y09 6ZAY	1P4U 1TU3 1X79 4N3Y 4N3Z 4Q9U
Enriched GO Terms of Interacting Partners?		Activin Receptor Complex Activin Receptor Activity, Type I Transforming Growth Factor Beta Receptor Activity, Type I Endosome Viral RNA Genome Replication Negative Stranded Viral RNA Replication Atg12-Atg5-Atg16 Complex Positive Regulation Of Cardiac Epithelial To Mesenchymal Transition Activin Binding Transmembrane Receptor Protein Serine/threonine Kinase Activity Regulation Of Endocytosis Regulation Of Receptor-mediated Endocytosis Pharyngeal System Development Viral Genome Replication Transforming Growth Factor Beta Binding Recycling Endosome Phagophore Assembly Site Membrane Regulation Of Postsynaptic Neurotransmitter Receptor Internalization Activin Receptor Signaling Pathway Ventricular Septum Morphogenesis Regulation Of Vesicle-mediated Transport Positive Regulation Of SMAD Protein Signal Transduction Protein Transport Growth Factor Binding SMAD Binding Endocardial Cushion Cell Fate Commitment Vacuole-isolation Membrane Contact Site Positive Regulation Of Epithelial To Mesenchymal Transition Establishment Of Protein Localization Organelle Assembly Reproductive Process Regulation Of SMAD Protein Signal Transduction Endocytic Vesicle Cardiac Septum Morphogenesis Early Endosome Regulation Of Receptor Internalization Positive Regulation Of Determination Of Dorsal Identity Vascular Endothelial Cell Proliferation Epicardium Morphogenesis Negative Regulation Of Kit Signaling Pathway Negative Regulation Of Mast Cell Cytokine Production Axo-dendritic Transport Autophagosome C-terminal Protein Lipidation Regulation Of Apoptotic Signaling Pathway Developmental Process Involved In Reproduction Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Proepicardium Development Angiogenesis Involved In Coronary Vascular Morphogenesis	Intracellular Protein Localization Vesicle-mediated Transport Golgi Vesicle Transport Protein Binding Early Endosome Membrane Protein Transport Establishment Of Protein Localization Endosome Intracellular Transport Regulation Of Vesicle-mediated Transport G Protein Activity Recycling Endosome Cellular Localization Establishment Of Localization In Cell Vesicle-mediated Transport In Synapse Intracellular Protein Transport Rab Protein Signal Transduction Post-Golgi Vesicle-mediated Transport Endosomal Transport Intracellular Vesicle Regulation Of Exocytosis Small GTPase Binding Positive Regulation Of Protein Metabolic Process Intracellular Signal Transduction GTPase Activity Early Endosome Post-translational Protein Modification Protein Localization To Cell Surface Presynapse Insulin-responsive Compartment Negative Regulation Of Exocytosis Golgi To Plasma Membrane Protein Transport Vacuolar Transport Synaptic Vesicle Endocytosis Cytoplasmic Vesicle Membrane Protein Localization To Organelle Nucleus Secretion Protein Modification Process Secretion By Cell Protein Polyubiquitination Presynaptic Endocytosis Regulation Of MRNA 3'-end Processing Endosome Membrane Protein Localization To Plasma Membrane Positive Regulation Of Translational Initiation Regulation Of Endosome Size Regulation Of Cellular Component Organization Exocytosis AP-1 Adaptor Complex
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