LYAR and ADSSL1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		LYAR	ADSSL1
Gene Name		Ly1 antibody reactive	adenylosuccinate synthase like 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus	Cytoplasm Cytosol
	Molecular Function	Protein Binding Poly(A) RNA Binding Metal Ion Binding	Magnesium Ion Binding GTPase Activity Adenylosuccinate Synthase Activity GTP Binding Phosphate Ion Binding Protein Homodimerization Activity Actin Filament Binding
	Biological Process		Immune System Process Purine Nucleobase Metabolic Process AMP Biosynthetic Process Aspartate Metabolic Process Glutamine Metabolic Process Purine Ribonucleoside Monophosphate Biosynthetic Process Response To Muscle Activity Cellular Response To Drug Response To Starvation 'de Novo' AMP Biosynthetic Process Small Molecule Metabolic Process IMP Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Cellular Response To Electrical Stimulus
Pathways			Purine ribonucleoside monophosphate biosynthesis Purine metabolism Metabolism of nucleotides
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: ADSSL1 BEND7 CD2 FGF18 PHF20L1 PRKRA SDCBP2 TERF1 TERF2 ZBTB16 ZHX1	2 interactors: AZIN1 LYAR
Entrez ID		55646	122622
HPRD ID		10064	12433
Ensembl ID		ENSG00000145220	ENSG00000185100
Uniprot IDs		Q9NX58	B3KTV4 Q8N142
PDB IDs			2GJO
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Telomeric Loop Formation Age-dependent Telomere Shortening Telomere Maintenance Via Telomere Shortening Replicative Cell Aging Regulation Of Nuclear Cell Cycle DNA Replication Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance RNA-dependent DNA Replication Positive Regulation Of Chondrocyte Differentiation Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Cartilage Development Negative Regulation Of DNA Replication Regulation Of Chondrocyte Differentiation Cell Aging Telomere Maintenance Positive Regulation Of Myeloid Dendritic Cell Activation Negative Regulation Of Chromosome Organization Regulation Of Cartilage Development Immune System Process Negative Regulation Of DNA Metabolic Process Developmental Process Regulation Of T Cell Differentiation Skeletal System Development Regulation Of DNA Replication Negative Regulation Of Biosynthetic Process Positive Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor Membrane Raft Polarization 'de Novo' AMP Biosynthetic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Positive Regulation Of Interferon-gamma Secretion Protection From Non-homologous End Joining At Telomere Regulation Of Lymphocyte Differentiation Membrane Raft Localization Telomere Capping Positive Regulation Of NK T Cell Differentiation Protein Localization To Chromosome, Telomeric Region AMP Biosynthetic Process Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor Male Germ-line Stem Cell Asymmetric Division Negative Regulation Of Telomere Maintenance Via Telomerase Regulation Of Myeloid Dendritic Cell Activation Cartilage Development Nucleobase-containing Compound Metabolic Process Aspartate Metabolic Process Regulation Of Chromosome Organization Heterocycle Metabolic Process	Positive Regulation Of Polyamine Transmembrane Transport Polyamine Biosynthetic Process Amine Biosynthetic Process Polyamine Metabolic Process Negative Regulation Of Protein Catabolic Process Cellular Biogenic Amine Metabolic Process Amine Metabolic Process
Tagcloud ?		34a abcf2 adhesions alg13 bioinformatics chance ctcf fak held kaplan ki67 meier michigan mir nbl neuroblastoma originates proteome proteomics searches seed sh shep sy5y sympathetic tetracycline tgm2 timm13 utr	abca7 apoe bin1 cd2ap cd33 cognitively cr1 epha1 fbxl2 hallmark haplotype intron load map2k4 modifier ms4a4a ms4a6e multifactorial picalm plink pomt2 ppp2r5c rabgef1 sh3kbp1 snp snx8 synj1 xpo1 xrn1
Tagcloud (Difference) ?		34a abcf2 adhesions alg13 bioinformatics chance ctcf fak held kaplan ki67 meier michigan mir nbl neuroblastoma originates proteome proteomics searches seed sh shep sy5y sympathetic tetracycline tgm2 timm13 utr	abca7 apoe bin1 cd2ap cd33 cognitively cr1 epha1 fbxl2 hallmark haplotype intron load map2k4 modifier ms4a4a ms4a6e multifactorial picalm plink pomt2 ppp2r5c rabgef1 sh3kbp1 snp snx8 synj1 xpo1 xrn1
Tagcloud (Intersection) ?