ADSSL1 and LYAR

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ADSSL1	LYAR
Gene Name		adenylosuccinate synthase like 1	Ly1 antibody reactive
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol	Nucleus Nucleolus
	Molecular Function	Magnesium Ion Binding GTPase Activity Adenylosuccinate Synthase Activity GTP Binding Phosphate Ion Binding Protein Homodimerization Activity Actin Filament Binding	Protein Binding Poly(A) RNA Binding Metal Ion Binding
	Biological Process	Immune System Process Purine Nucleobase Metabolic Process AMP Biosynthetic Process Aspartate Metabolic Process Glutamine Metabolic Process Purine Ribonucleoside Monophosphate Biosynthetic Process Response To Muscle Activity Cellular Response To Drug Response To Starvation 'de Novo' AMP Biosynthetic Process Small Molecule Metabolic Process IMP Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Cellular Response To Electrical Stimulus
Pathways		Purine ribonucleoside monophosphate biosynthesis Purine metabolism Metabolism of nucleotides
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: AZIN1 LYAR	11 interactors: ADSSL1 BEND7 CD2 FGF18 PHF20L1 PRKRA SDCBP2 TERF1 TERF2 ZBTB16 ZHX1
Entrez ID		122622	55646
HPRD ID		12433	10064
Ensembl ID		ENSG00000185100	ENSG00000145220
Uniprot IDs		B3KTV4 Q8N142	Q9NX58
PDB IDs		2GJO
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Polyamine Transmembrane Transport Polyamine Biosynthetic Process Amine Biosynthetic Process Polyamine Metabolic Process Negative Regulation Of Protein Catabolic Process Cellular Biogenic Amine Metabolic Process Amine Metabolic Process	Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Telomeric Loop Formation Age-dependent Telomere Shortening Telomere Maintenance Via Telomere Shortening Replicative Cell Aging Regulation Of Nuclear Cell Cycle DNA Replication Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance RNA-dependent DNA Replication Positive Regulation Of Chondrocyte Differentiation Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Cartilage Development Negative Regulation Of DNA Replication Regulation Of Chondrocyte Differentiation Cell Aging Telomere Maintenance Positive Regulation Of Myeloid Dendritic Cell Activation Negative Regulation Of Chromosome Organization Regulation Of Cartilage Development Immune System Process Negative Regulation Of DNA Metabolic Process Developmental Process Regulation Of T Cell Differentiation Skeletal System Development Regulation Of DNA Replication Negative Regulation Of Biosynthetic Process Positive Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor Membrane Raft Polarization 'de Novo' AMP Biosynthetic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Positive Regulation Of Interferon-gamma Secretion Protection From Non-homologous End Joining At Telomere Regulation Of Lymphocyte Differentiation Membrane Raft Localization Telomere Capping Positive Regulation Of NK T Cell Differentiation Protein Localization To Chromosome, Telomeric Region AMP Biosynthetic Process Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor Male Germ-line Stem Cell Asymmetric Division Negative Regulation Of Telomere Maintenance Via Telomerase Regulation Of Myeloid Dendritic Cell Activation Cartilage Development Nucleobase-containing Compound Metabolic Process Aspartate Metabolic Process Regulation Of Chromosome Organization Heterocycle Metabolic Process
Tagcloud ?		abca7 apoe bin1 cd2ap cd33 cognitively cr1 epha1 fbxl2 hallmark haplotype intron load map2k4 modifier ms4a4a ms4a6e multifactorial picalm plink pomt2 ppp2r5c rabgef1 sh3kbp1 snp snx8 synj1 xpo1 xrn1	34a abcf2 adhesions alg13 bioinformatics chance ctcf fak held kaplan ki67 meier michigan mir nbl neuroblastoma originates proteome proteomics searches seed sh shep sy5y sympathetic tetracycline tgm2 timm13 utr
Tagcloud (Difference) ?		abca7 apoe bin1 cd2ap cd33 cognitively cr1 epha1 fbxl2 hallmark haplotype intron load map2k4 modifier ms4a4a ms4a6e multifactorial picalm plink pomt2 ppp2r5c rabgef1 sh3kbp1 snp snx8 synj1 xpo1 xrn1	34a abcf2 adhesions alg13 bioinformatics chance ctcf fak held kaplan ki67 meier michigan mir nbl neuroblastoma originates proteome proteomics searches seed sh shep sy5y sympathetic tetracycline tgm2 timm13 utr
Tagcloud (Intersection) ?