LYAR and PHF20L1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		LYAR	PHF20L1
Gene Name		Ly1 antibody reactive	PHD finger protein 20-like 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus
	Molecular Function	Protein Binding Poly(A) RNA Binding Metal Ion Binding	Protein Binding Zinc Ion Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: ADSSL1 BEND7 CD2 FGF18 PHF20L1 PRKRA SDCBP2 TERF1 TERF2 ZBTB16 ZHX1	9 interactors: APP CASP10 ELAVL4 KDM1A LYAR TERT UBC WWP1 ZNF471
Entrez ID		55646	51105
HPRD ID		10064	15125
Ensembl ID		ENSG00000145220	ENSG00000129292
Uniprot IDs		Q9NX58	A8MW92 F8W9L8 Q9H8G4
PDB IDs			2EQM 2EQU 2JTF
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Telomeric Loop Formation Age-dependent Telomere Shortening Telomere Maintenance Via Telomere Shortening Replicative Cell Aging Regulation Of Nuclear Cell Cycle DNA Replication Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance RNA-dependent DNA Replication Positive Regulation Of Chondrocyte Differentiation Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Cartilage Development Negative Regulation Of DNA Replication Regulation Of Chondrocyte Differentiation Cell Aging Telomere Maintenance Positive Regulation Of Myeloid Dendritic Cell Activation Negative Regulation Of Chromosome Organization Regulation Of Cartilage Development Immune System Process Negative Regulation Of DNA Metabolic Process Developmental Process Regulation Of T Cell Differentiation Skeletal System Development Regulation Of DNA Replication Negative Regulation Of Biosynthetic Process Positive Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor Membrane Raft Polarization 'de Novo' AMP Biosynthetic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Positive Regulation Of Interferon-gamma Secretion Protection From Non-homologous End Joining At Telomere Regulation Of Lymphocyte Differentiation Membrane Raft Localization Telomere Capping Positive Regulation Of NK T Cell Differentiation Protein Localization To Chromosome, Telomeric Region AMP Biosynthetic Process Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor Male Germ-line Stem Cell Asymmetric Division Negative Regulation Of Telomere Maintenance Via Telomerase Regulation Of Myeloid Dendritic Cell Activation Cartilage Development Nucleobase-containing Compound Metabolic Process Aspartate Metabolic Process Regulation Of Chromosome Organization Heterocycle Metabolic Process	Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway RNA Metabolic Process Gene Expression Negative Regulation Of Cellular Metabolic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Regulation Of Primitive Erythrocyte Differentiation Negative Regulation Of Production Of SiRNA Involved In RNA Interference Negative Regulation Of Gene Expression Negative Regulation Of RNA Interference Synaptic Growth At Neuromuscular Junction Transcription, RNA-templated RNA Processing Regulation Of Apoptotic Process Regulation Of RNA Metabolic Process Regulation Of Signal Transduction Notch Signaling Pathway Telomere Formation Via Telomerase Collateral Sprouting In Absence Of Injury Age-dependent Telomere Shortening Positive Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Regulation Of Cell Death Regulation Of Protein Binding Positive Regulation Of Wnt Signaling Pathway Heterocycle Metabolic Process Telomere Maintenance Via Telomere Shortening Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Signaling Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Collateral Sprouting Axon Midline Choice Point Recognition Cellular Nitrogen Compound Metabolic Process Viral Life Cycle Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Intracellular Receptor Signaling Pathway Innate Immune Response Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Telomere Assembly Axon Choice Point Recognition Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Histone H3-K9 Demethylation Negative Regulation Of Histone H3-K4 Methylation Histone H3-K4 Demethylation Negative Regulation Of Protein Metabolic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Tagcloud ?		34a abcf2 adhesions alg13 bioinformatics chance ctcf fak held kaplan ki67 meier michigan mir nbl neuroblastoma originates proteome proteomics searches seed sh shep sy5y sympathetic tetracycline tgm2 timm13 utr	10kb appbp2 arhgap32 bcas3 breakpoints ccdc49 coamplification col14a1 coregulator ddx5 depdc6 deptor enpp2 hoxb9 lasp1 leukaemias nrip1 oprd1 painting pcgf2 plec1 skap1 taok1 tiam1 timm23 trps1 unamplified usp32 zmym4
Tagcloud (Difference) ?		34a abcf2 adhesions alg13 bioinformatics chance ctcf fak held kaplan ki67 meier michigan mir nbl neuroblastoma originates proteome proteomics searches seed sh shep sy5y sympathetic tetracycline tgm2 timm13 utr	10kb appbp2 arhgap32 bcas3 breakpoints ccdc49 coamplification col14a1 coregulator ddx5 depdc6 deptor enpp2 hoxb9 lasp1 leukaemias nrip1 oprd1 painting pcgf2 plec1 skap1 taok1 tiam1 timm23 trps1 unamplified usp32 zmym4
Tagcloud (Intersection) ?