LYAR and PHF20L1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		LYAR	PHF20L1
Description		Ly1 antibody reactive	PHD finger protein 20 like 1
Image
GO Annotations	Cellular Component	Photoreceptor Outer Segment Nucleus Nucleoplasm Nucleolus Cytoplasm Cell Projection	Nucleus Nucleoplasm NSL Complex
	Molecular Function	DNA Binding RNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding DNA-binding Transcription Factor Binding Transcription Regulator Inhibitor Activity	Protein Binding Zinc Ion Binding Metal Ion Binding Methylation-dependent Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Immune System Process RRNA Processing Innate Immune Response Negative Regulation Of Innate Immune Response Positive Regulation Of Transcription By RNA Polymerase I Erythrocyte Development Positive Regulation Of Phagocytosis	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Catabolic Process
Pathways			Formation of WDR5-containing histone-modifying complexes
Drugs
Diseases
GWAS		Disease progression in age-related macular degeneration ( 29346644)	Body fat percentage ( 31752434) Mean reticulocyte volume ( 32888494) Metabolite levels ( 23823483) Thyroid stimulating hormone levels ( 32769997) Type 1 diabetes (age at diagnosis) ( 33179336)
Interacting Genes		16 interacting genes: ADSS1 BEND7 CD2 FGF18 GSK3B OGT PDE4B PHF20L1 PRKRA SDCBP2 SNRPA SREK1IP1 TERF1 TERF2 ZBTB16 ZHX1	10 interacting genes: APP CASP10 ELAVL4 KDM1A LRRK2 LYAR TERT UBC WWP1 ZNF471
Entrez ID		55646	51105
HPRD ID		10064	15125
Ensembl ID		ENSG00000145220	ENSG00000129292
Uniprot IDs		Q9NX58	A0A0A0MQS0 A0A0A8K9A6 A8MW92 F8W9L8 Q9H8G4
PDB IDs		6ZMI 6ZMO 6ZVH	2EQM 2EQU 2JTF 6L0X 6L10 6L1C 6L1F 6L1I 6L1P
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Shelterin Complex Telomerase Activity Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Nuclear Telomere Cap Complex Telomeric D-loop Disassembly Double-stranded Telomeric DNA Binding G-rich Strand Telomeric DNA Binding Telomeric Loop Disassembly NSL Complex Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Telomere Capping Positive Regulation Of Chondrocyte Differentiation Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Protein Catabolic Process RNA-templated DNA Biosynthetic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Telomeric DNA Binding Protein Homodimerization Activity Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Biosynthetic Process Positive Regulation Of Cartilage Development Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Telomere Maintenance Identical Protein Binding Nucleoplasm Regulation Of Proteasomal Protein Catabolic Process Regulation Of Microtubule Anchoring At Centrosome Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly Telomere Cap Complex Negative Regulation Of Telomere Maintenance Via Recombination Axonal Transport Of Messenger Ribonucleoprotein Complex Negative Regulation Of Telomere Single Strand Break Repair Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Negative Regulation Of Macromolecule Metabolic Process Male Germ Cell Nucleus Regulation Of Chondrocyte Differentiation Regulation Of Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Myeloid Dendritic Cell Activation Negative Regulation Of Metabolic Process Superior Temporal Gyrus Development	Golgi-associated Vesicle Growth Cone Cellular Response To Catecholamine Stimulus Cellular Response To Manganese Ion Perikaryon Regulation Of Apoptotic Signaling Pathway Response To Catecholamine Response To Manganese Ion Macromolecule Metabolic Process Positive Regulation Of Endocytosis Telomeric DNA Binding Neuron Maturation Regulation Of Intrinsic Apoptotic Signaling Pathway Locomotory Behavior Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Amyloid-beta Complex Cell Projection Morphogenesis Growth Cone Lamellipodium Regulation Of Neuron Apoptotic Process Regulation Of Response To Calcium Ion Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Amylin Binding Neuron Projection Morphogenesis Positive Regulation Of Toll Signaling Pathway Regulation Of CAMP/PKA Signal Transduction Cellular Response To CAMP Modulation Of Excitatory Postsynaptic Potential TERT-RMRP Complex Template-free RNA Nucleotidyltransferase Negative Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Transdifferentiation RNA-directed RNA Polymerase Complex Positive Regulation Of Stem Cell Proliferation SiRNA Transcription Regulation Of Neuroblast Proliferation Cellular Response To Curcumin Caveola Neck GTP-dependent Protein Kinase Activity Wnt Signalosome Assembly Myeloid Cell Development Negative Regulation Of RNA Metabolic Process Regulation Of Endocytosis Regulation Of Apoptotic Process Positive Regulation Of Neuron Apoptotic Process Regulation Of Wnt Signaling Pathway Acetylcholine Receptor Activator Activity Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Response To Metal Ion
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?