ADSS1 and AZIN1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		ADSS1	AZIN1
Description		adenylosuccinate synthase 1	antizyme inhibitor 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Nucleus Cytoplasm Cytosol
	Molecular Function	Nucleotide Binding Magnesium Ion Binding GTPase Activity Adenylosuccinate Synthase Activity Protein Binding GTP Binding Ligase Activity Phosphate Ion Binding Identical Protein Binding Metal Ion Binding Actin Filament Binding	Catalytic Activity Ornithine Decarboxylase Activity Protein Binding Ornithine Decarboxylase Activator Activity
	Biological Process	Immune System Process Purine Nucleotide Metabolic Process Purine Nucleotide Biosynthetic Process AMP Biosynthetic Process Aspartate Metabolic Process Glutamine Metabolic Process Response To Muscle Activity Response To Starvation 'de Novo' AMP Biosynthetic Process AMP Salvage IMP Metabolic Process Cellular Response To Electrical Stimulus Cellular Response To Xenobiotic Stimulus	Polyamine Biosynthetic Process Putrescine Biosynthetic Process From Arginine, Via Ornithine Negative Regulation Of Protein Catabolic Process Positive Regulation Of Polyamine Transmembrane Transport
Pathways		Purine ribonucleoside monophosphate biosynthesis	Regulation of ornithine decarboxylase (ODC)
Drugs		Aspartic acid Hadacidin 6-O-Phosphoryl Inosine Monophosphate Guanosine-5'-Triphosphate Guanosine-5'-Diphosphate Adenylosuccinic acid Inosinic Acid Alanosine
Diseases
GWAS			Airway imaging phenotypes ( 26030696) Apolipoprotein A1 levels ( 32203549) Granulocyte count ( 27863252) HDL cholesterol levels ( 32203549) Immature fraction of reticulocytes ( 32888494) Mean platelet volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Neutrophil count ( 27863252) PR interval ( 32439900) QT interval ( 24952745) Serum alkaline phosphatase levels ( 33547301) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) TPE interval (resting) ( 32386560) Waist circumference adjusted for body mass index ( 28552196) White blood cell count ( 32888494)
Interacting Genes		2 interacting genes: AZIN1 LYAR	7 interacting genes: ABCC2 ADSS1 BMAL1 CDKN2A FANCA FANCC KHDRBS1
Entrez ID		122622	51582
HPRD ID		12433	07443
Ensembl ID		ENSG00000185100	ENSG00000155096
Uniprot IDs		B3KTV4 Q8N142	A0A804HLH4 B3KTF6 O14977
PDB IDs			4ZGZ
Enriched GO Terms of Interacting Partners?		Ornithine Decarboxylase Activity Ornithine Decarboxylase Activator Activity Positive Regulation Of Polyamine Transmembrane Transport Putrescine Biosynthetic Process From Arginine, Via Ornithine MRNA (adenine-N1-)-methyltransferase Activity TRNA (m1A) Methyltransferase Complex TRNA (adenine(58)-N1)-methyltransferase Activity Putrescine Biosynthetic Process Putrescine Metabolic Process Polyamine Biosynthetic Process Arginine Metabolic Process Polyamine Metabolic Process	Fanconi Anaemia Nuclear Complex Cellular Senescence Ligase Inhibitor Activity Bilirubin Transmembrane Transporter Activity Bilirubin Transport Interstrand Cross-link Repair Grb2-Sos Complex
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?