ZDHHC7 and CYB561

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZDHHC7	CYB561
Description		zDHHC palmitoyltransferase 7	cytochrome b561
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Endoplasmic Reticulum Golgi Apparatus Membrane	Lysosomal Membrane Membrane Cytoplasmic Vesicle Chromaffin Granule Membrane
	Molecular Function	Protein Binding Palmitoyltransferase Activity Transferase Activity Acyltransferase Activity Protein-cysteine S-myristoyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity Protein-cysteine S-stearoyltransferase Activity	Protein Binding Oxidoreductase Activity Metal Ion Binding Transmembrane Monodehydroascorbate Reductase Activity
	Biological Process	Protein Targeting To Membrane Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Catabolic Process Positive Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of D-glucose Transmembrane Transport Peptidyl-L-cysteine S-palmitoylation Protein Palmitoylation Androgen Receptor Signaling Pathway Polarized Epithelial Cell Differentiation Steroid Hormone Receptor Signaling Pathway Glucose Import In Response To Insulin Stimulus Progesterone Receptor Signaling Pathway Protein Localization To Plasma Membrane Regulation Of Protein Localization To Cell-cell Junction Regulation Of Fas Signaling Pathway Regulation Of Protein Localization To Plasma Membrane D-glucose Transmembrane Transport	Intracellular Iron Ion Homeostasis Electron Transport Chain Ascorbate Homeostasis
Pathways		Extra-nuclear estrogen signaling
Drugs
Diseases
GWAS		Height ( 18391951 25282103) Stress sensitivity (neuroticism score x major depressive disorder status interaction) ( 30571770)	Cerebrospinal fluid levels of Alzheimer's disease-related proteins ( 25340798) Diastolic blood pressure ( 28739976)
Interacting Genes		5 interacting genes: APP CYB561 LAT PBX2 YIPF1	60 interacting genes: ANKRD46 AQP6 BEST2 BET1 BIK BNIP1 CD79A CDIPT CLDN9 CMTM2 CREB3 DARS2 EBP EDA EFNA5 EHHADH ERG28 ERGIC3 FAM209A FKBP8 GGT7 GIMAP5 GOSR2 GPR152 GPX8 HMOX1 LHFPL5 LMNA LPAR3 OPRM1 ORMDL2 PLP2 REEP6 RNF5 SCD SEC22A SERP2 SLC19A3 SLC35H1 SLC38A7 SLC39A1 SLC39A2 SMIM1 SSMEM1 STX3 SYNJ2BP TM4SF18 TMEM11 TMEM128 TMEM14B TMEM179B TMEM242 TMEM65 TMPPE TREX1 TSNARE1 UBE2J1 VAPA VAPB ZDHHC7
Entrez ID		55625	1534
HPRD ID		15722	02485
Ensembl ID		ENSG00000153786	ENSG00000008283
Uniprot IDs		Q9NXF8	B3KTA1 J3QRH5 P49447
PDB IDs
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Immune Response Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Regulation Of Type II Interferon Production Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Response To Bacterium Defense Response Positive Regulation Of Type II Interferon Production Defense Response To Bacterium Lipoprotein Particle Myeloid Leukocyte Activation Notch Signaling Pathway Chromatin Binding Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Leukocyte Activation Positive Regulation Of Protein Import Vesicle-mediated Transport Cell Activation Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Immune Effector Process Regulation Of Generation Of Precursor Metabolites And Energy Positive Regulation Of Transcription By RNA Polymerase II Ascorbate Homeostasis B Cell Differentiation Dendritic Cell Differentiation Plasmacytoid Dendritic Cell Differentiation Lymphocyte Activation MAML1-RBP-Jkappa- ICN1 Complex Positive Regulation Of Ephrin Receptor Signaling Pathway Endocardium Morphogenesis Blood Vessel Endothelial Cell Fate Specification Blood Vessel Lumenization Arterial Endothelial Cell Fate Commitment Auditory Receptor Cell Fate Commitment Regulation Of Cell Adhesion Involved In Heart Morphogenesis TCR Signalosome Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum SNAP Receptor Activity SNARE Complex Membrane Fusion Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Binding Organelle Membrane Fusion FFAT Motif Binding Mitochondrial Membrane Golgi Vesicle Transport Endoplasmic Reticulum Organization Membrane Organization Organelle Fusion COPII-coated Vesicle Budding Endoplasmic Reticulum-plasma Membrane Tethering Organelle Localization By Membrane Tethering Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Endoplasmic Reticulum Localization Membrane Docking Vesicle Fusion Lipid Biosynthetic Process Host-mediated Activation Of Viral Genome Replication Positive Regulation Of Collateral Sprouting Host-mediated Perturbation Of Viral Genome Replication Progesterone Receptor Signaling Pathway Vesicle Organization
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