PIP4P2 and GTF2IRD1

Number of citations of the paper that reports this interaction (PubMedID 26275350)
0

Data Source:
BioGRID (two hybrid)

		PIP4P2	GTF2IRD1
Description		phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2	GTF2I repeat domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Plasma Membrane Membrane Phagocytic Vesicle Membrane Cytoplasmic Vesicle Late Endosome Membrane	Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Binding Hydrolase Activity Phosphatidylinositol-4,5-bisphosphate 4-phosphatase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding
	Biological Process	Lipid Metabolic Process Phosphatidylinositol Dephosphorylation Negative Regulation Of Phagocytosis	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Transcription By RNA Polymerase II Transition Between Slow And Fast Fiber
Pathways
Drugs
Diseases
GWAS			Age at suicide ( 31476763) Aluminium levels ( 26025379) General factor of neuroticism ( 30867560) Neuroticism ( 29255261) Rheumatoid arthritis ( 32723749) Severe influenza A (H1N1) infection ( 26379185) Sjögren's syndrome ( 24097066) Systemic lupus erythematosus ( 26663301 28714469) Triglyceride levels ( 32203549)
Interacting Genes		10 interacting genes: GTF2IRD1 ITCH NEDD4 NEDD4L RIPPLY3 SLC10A6 TNF TSG101 YAP1 ZFYVE27	24 interacting genes: ALMS1 ATP2C1 CDK20 DCAF6 EXOSC4 GORASP2 HDAC3 HTRA4 KPNA1 KPNA2 KPNA3 KPNA4 MRFAP1L1 PIAS1 PIAS2 PIP4P2 PKP1 PKP2 SELENOS SMAD3 SPTLC1 UBC USP20 ZMYM5
Entrez ID		55529	9569
HPRD ID		13233	08379
Ensembl ID		ENSG00000155099	ENSG00000006704
Uniprot IDs		Q8N4L2	E9PFE2 Q9UHL9
PDB IDs			2D99 2DN5 2DZQ 2DZR
Enriched GO Terms of Interacting Partners?		Sodium Channel Inhibitor Activity Receptor Internalization Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Protein Catabolic Process Negative Regulation Of Potassium Ion Export Across Plasma Membrane Protein Monoubiquitination Regulation Of Cell Growth Potassium Channel Inhibitor Activity Regulation Of Growth Regulation Of Potassium Ion Export Across Plasma Membrane Negative Regulation Of Sodium Ion Transport Cell Population Proliferation Proline-rich Region Binding Negative Regulation Of DNA-templated Transcription Receptor Catabolic Process Regulation Of Protein Catabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transmembrane Transport Negative Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of RNA Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Viral Budding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Potassium Ion Transport Cellular Response To Radiation Negative Regulation Of Biosynthetic Process Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Receptor-mediated Endocytosis Positive Regulation Of Cell Growth Positive Regulation Of Developmental Growth Sodium Ion Transport Plasma Membrane Neuromuscular Junction Development Regulation Of Cellular Component Organization Regulation Of Protein Localization To Cell Surface Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Intracellular Receptor Signaling Pathway Multivesicular Body Receptor Metabolic Process Catabolic Process Proteolysis Protein Polyubiquitination Regulation Of Plasma Membrane Bounded Cell Projection Organization Vesicle-mediated Transport Mesenchyme Development Negative Regulation Of Metabolic Process Proteolysis Involved In Protein Catabolic Process	NLS-dependent Protein Nuclear Import Complex Nuclear Import Signal Receptor Activity Nuclear Localization Sequence Binding NLS-bearing Protein Import Into Nucleus Viral Penetration Into Host Nucleus Protein Import Into Nucleus Import Into Nucleus Intermediate Filament Binding Intracellular Transport Of Virus Intermediate Filament Bundle Assembly Desmosome Assembly Nucleoplasm Host Cell Protein Localization To Nucleus SUMO Ligase Activity Positive Regulation Of Protein Localization To Cell Periphery Desmosome Organization Nuclear Pore Ubiquitin-specific Protease Binding Positive Regulation Of Protein Localization SUMO Transferase Activity Nuclear Transport Nucleocytoplasmic Transport SMAD Protein Signal Transduction Desmosome Ubiquitin Protein Ligase Binding Intracellular Protein Transport Cellular Localization Collagen Type XV Trimer Establishment Of Protein Localization To Organelle Negative Regulation Of Lung Blood Pressure Nuclear Mineralocorticoid Receptor Binding Positive Regulation Of Protein Import Into Nucleus Regulation Of Protein Localization To Cell Periphery Maintenance Of Protein Localization At Cell Tip Positive Regulation Of Ferroptosis
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