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PIP4P2
Description
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2
Image
No pdb structure
GO Annotations
Cellular Component
Lysosome
Lysosomal Membrane
Endosome
Plasma Membrane
Membrane
Phagocytic Vesicle Membrane
Cytoplasmic Vesicle
Late Endosome Membrane
Molecular Function
Protein Binding
Hydrolase Activity
Phosphatidylinositol-4,5-bisphosphate 4-phosphatase Activity
Biological Process
Lipid Metabolic Process
Phosphatidylinositol Dephosphorylation
Negative Regulation Of Phagocytosis
Pathways
Drugs
Diseases
GWAS
Novel Interacting Genes
1 novel interacting genes:
MMP16
Interacting Genes
10 interacting genes:
GTF2IRD1
ITCH
NEDD4
NEDD4L
RIPPLY3
SLC10A6
TNF
TSG101
YAP1
ZFYVE27
Entrez ID
55529
HPRD ID
13233
Ensembl ID
ENSG00000155099
Uniprot IDs
Q8N4L2
PDB IDs
Enriched GO Terms of Interacting Partners
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Sodium Channel Inhibitor Activity
Receptor Internalization
Negative Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Protein Catabolic Process
Negative Regulation Of Potassium Ion Export Across Plasma Membrane
Protein Monoubiquitination
Regulation Of Cell Growth
Potassium Channel Inhibitor Activity
Regulation Of Growth
Regulation Of Potassium Ion Export Across Plasma Membrane
Negative Regulation Of Sodium Ion Transport
Cell Population Proliferation
Proline-rich Region Binding
Negative Regulation Of DNA-templated Transcription
Receptor Catabolic Process
Regulation Of Protein Catabolic Process
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Transmembrane Transport
Negative Regulation Of Potassium Ion Transmembrane Transport
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Viral Budding
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Potassium Ion Transport
Cellular Response To Radiation
Negative Regulation Of Biosynthetic Process
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Receptor-mediated Endocytosis
Positive Regulation Of Cell Growth
Positive Regulation Of Developmental Growth
Sodium Ion Transport
Plasma Membrane
Neuromuscular Junction Development
Regulation Of Cellular Component Organization
Regulation Of Protein Localization To Cell Surface
Negative Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Intracellular Receptor Signaling Pathway
Multivesicular Body
Receptor Metabolic Process
Catabolic Process
Proteolysis
Protein Polyubiquitination
Regulation Of Plasma Membrane Bounded Cell Projection Organization
Vesicle-mediated Transport
Mesenchyme Development
Negative Regulation Of Metabolic Process
Proteolysis Involved In Protein Catabolic Process
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