PIP4P2 and RIPPLY3

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		PIP4P2	RIPPLY3
Description		phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2	ripply transcriptional repressor 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Plasma Membrane Membrane Phagocytic Vesicle Membrane Cytoplasmic Vesicle Late Endosome Membrane	Nucleus
	Molecular Function	Protein Binding Hydrolase Activity Phosphatidylinositol-4,5-bisphosphate 4-phosphatase Activity	Protein Binding
	Biological Process	Lipid Metabolic Process Phosphatidylinositol Dephosphorylation Negative Regulation Of Phagocytosis	Negative Regulation Of Transcription By RNA Polymerase II Heart Development Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Embryonic Pattern Specification Pharyngeal System Development
Pathways
Drugs
Diseases
GWAS
Interacting Genes		10 interacting genes: GTF2IRD1 ITCH NEDD4 NEDD4L RIPPLY3 SLC10A6 TNF TSG101 YAP1 ZFYVE27	22 interacting genes: CEP76 COMMD1 CRTAP EIF4A1 EIF4A2 HSP90AA1 INCA1 MAP4K4 MCRS1 MLEC ORC2 PIP4P2 PSMB1 RBCK1 RBP4 RGPD6 RHOBTB3 SNRNP70 STXBP1 TIFA TRAF2 WASL
Entrez ID		55529	53820
HPRD ID		13233	10923
Ensembl ID		ENSG00000155099	ENSG00000183145
Uniprot IDs		Q8N4L2	P57055
PDB IDs
Enriched GO Terms of Interacting Partners?		Sodium Channel Inhibitor Activity Receptor Internalization Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Protein Catabolic Process Negative Regulation Of Potassium Ion Export Across Plasma Membrane Protein Monoubiquitination Regulation Of Cell Growth Potassium Channel Inhibitor Activity Regulation Of Growth Regulation Of Potassium Ion Export Across Plasma Membrane Negative Regulation Of Sodium Ion Transport Cell Population Proliferation Proline-rich Region Binding Negative Regulation Of DNA-templated Transcription Receptor Catabolic Process Regulation Of Protein Catabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transmembrane Transport Negative Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of RNA Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Viral Budding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Potassium Ion Transport Cellular Response To Radiation Negative Regulation Of Biosynthetic Process Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Receptor-mediated Endocytosis Positive Regulation Of Cell Growth Positive Regulation Of Developmental Growth Sodium Ion Transport Plasma Membrane Neuromuscular Junction Development Regulation Of Cellular Component Organization Regulation Of Protein Localization To Cell Surface Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Intracellular Receptor Signaling Pathway Multivesicular Body Receptor Metabolic Process Catabolic Process Proteolysis Protein Polyubiquitination Regulation Of Plasma Membrane Bounded Cell Projection Organization Vesicle-mediated Transport Mesenchyme Development Negative Regulation Of Metabolic Process Proteolysis Involved In Protein Catabolic Process
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