TRIM36 and GRB7

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TRIM36	GRB7
Gene Name		tripartite motif containing 36	growth factor receptor-bound protein 7
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Acrosomal Vesicle Cytoskeleton Extracellular Vesicular Exosome	Cytosol Plasma Membrane Focal Adhesion Cytoplasmic Stress Granule Cell Projection
	Molecular Function	Ubiquitin-protein Transferase Activity Zinc Ion Binding Ligase Activity	RNA Binding SH3/SH2 Adaptor Activity Protein Binding Protein Kinase Binding Phosphatidylinositol Binding Identical Protein Binding
	Biological Process	Acrosome Reaction Protein Ubiquitination Regulation Of Cell Cycle	Epidermal Growth Factor Receptor Signaling Pathway Blood Coagulation Positive Regulation Of Signal Transduction Negative Regulation Of Translation Positive Regulation Of Cell Migration Stress Granule Assembly Leukocyte Migration
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System	Signaling by PDGF Signaling by SCF-KIT Signaling by ERBB2 Downstream signal transduction GRB7 events in ERBB2 signaling Tie2 Signaling Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: EIF4A2 GLRX3 GRB7 TRAF3IP3 UBC UBE2D2 UBE2H ZMAT2 ZNF417 ZNF587	39 interactors: A1BG AGAP1 ATP5B CALM1 CAV1 CPNE6 DOCK7 DYNC1I1 EGFR ERBB2 ERBB3 FGB FLAD1 GNB2 GRB2 HADHB INSR KCTD6 KIT KMT2B LAX1 LY6G6F MAP3K14 MSH2 PDGFRB PDHB PHAX PKM PTK2 RET RND1 RPS2 SETDB1 SHC1 TEK TLE1 TMSB4X TRIM36 ZBTB16
Entrez ID		55521	2886
HPRD ID		15554	03311
Ensembl ID		ENSG00000152503	ENSG00000141738
Uniprot IDs		E9PBG3 E9PFI8 Q9NQ86	Q14451
PDB IDs			1MW4 1WGR 2L4K 2QMS 3PQZ
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Protein K48-linked Ubiquitination Cellular Macromolecule Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Negative Regulation Of RNA-directed RNA Polymerase Activity Cellular Response To Hypoxia Ubiquitin-dependent Protein Catabolic Process Cellular Response To Decreased Oxygen Levels Modification-dependent Protein Catabolic Process Toll-like Receptor Signaling Pathway Cellular Response To Oxygen Levels Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Ubiquitination Pattern Recognition Receptor Signaling Pathway Protein Modification By Small Protein Conjugation Innate Immune Response-activating Signal Transduction Protein Catabolic Process Activation Of Innate Immune Response Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Gene Expression Positive Regulation Of Innate Immune Response Catabolic Process Regulation Of Innate Immune Response Negative Regulation Of Cardiac Muscle Hypertrophy Regulation Of Translation Negative Regulation Of Muscle Hypertrophy Viral Protein Processing Response To Hypoxia Negative Regulation Of Transferase Activity Stress Granule Assembly Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Notch Receptor Processing Protein K11-linked Ubiquitination Virion Assembly Negative Regulation Of Biosynthetic Process Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Nuclear-transcribed MRNA Poly(A) Tail Shortening Cytokine-mediated Signaling Pathway Glycogen Biosynthetic Process Intracellular Transport Of Virus	Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Cell Adhesion Peptidyl-tyrosine Phosphorylation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Phosphorus Metabolic Process Positive Regulation Of Phosphorylation Positive Regulation Of Catalytic Activity Positive Regulation Of Transferase Activity Regulation Of Phosphorylation Positive Regulation Of Protein Phosphorylation Intracellular Signal Transduction Immune System Process Regulation Of MAPK Cascade Regulation Of Kinase Activity Positive Regulation Of Kinase Activity Fibroblast Growth Factor Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Fc Receptor Signaling Pathway Regulation Of Protein Phosphorylation Positive Regulation Of Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Positive Regulation Of Protein Modification Process Regulation Of MAP Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Response To Fibroblast Growth Factor Regulation Of Protein Kinase Activity Neurotrophin TRK Receptor Signaling Pathway Wound Healing Immune Response-regulating Signaling Pathway Neurotrophin Signaling Pathway Positive Regulation Of Protein Kinase Activity Positive Regulation Of Protein Metabolic Process Fc-epsilon Receptor Signaling Pathway Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Signal Transduction Regulation Of Cellular Ketone Metabolic Process Regulation Of Catalytic Activity Regulation Of Immune System Process Regulation Of Signal Transduction Response To Wounding Regulation Of Cellular Amino Acid Metabolic Process Positive Regulation Of Protein Serine/threonine Kinase Activity Peptidyl-amino Acid Modification Signal Transduction By Phosphorylation Positive Regulation Of Cellular Metabolic Process Response To Hormone Regulation Of Cellular Protein Metabolic Process
Tagcloud ?		acsl androgen ar auc cancerous captured crp css eralpha estrogen favorable fox gleason klf4 microdissection naive oct oct1 powerful predict prostate psa separately set sets sox2 stromal validation	adapter appears avidly bear bps conversely denote domain domains dramatically existence grb10 grb14 homology interact interaction interacts ir location loop obvious paired pleckstrin resemblance sh2 summary unidentified y1150f y1151f
Tagcloud (Difference) ?		acsl androgen ar auc cancerous captured crp css eralpha estrogen favorable fox gleason klf4 microdissection naive oct oct1 powerful predict prostate psa separately set sets sox2 stromal validation	adapter appears avidly bear bps conversely denote domain domains dramatically existence grb10 grb14 homology interact interaction interacts ir location loop obvious paired pleckstrin resemblance sh2 summary unidentified y1150f y1151f
Tagcloud (Intersection) ?