ETNK1 and CAMLG

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ETNK1	CAMLG
Description		ethanolamine kinase 1	calcium modulating ligand
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Membrane	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane GET Complex
	Molecular Function	Nucleotide Binding Ethanolamine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity	Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Lipid Metabolic Process Phosphatidylethanolamine Biosynthetic Process Phospholipid Biosynthetic Process	B Cell Homeostasis Receptor Recycling Defense Response Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Vesicle-mediated Transport Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Insertion Into ER Membrane Protein Stabilization Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways		Synthesis of PE	Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs			Cyclosporine Voclosporin
Diseases
GWAS		Automobile speeding propensity ( 30643258) Chronotype ( 30696823) Mortality in sepsis ( 27639821) Precuneus cortex volume ( 31530798) Refractive error ( 32231278) Triglyceride levels ( 32203549)	Height ( 18391951)
Interacting Genes		6 interacting genes: CAMLG SGTA SGTB SLC51B UBQLN1 UBQLN2	21 interacting genes: ADIPOQ AGR2 BCL2L13 EGFR ETNK1 F11R GET1 HSP90B1 HSPA13 KCNE4 LAT LCN2 OCIAD1 PBXIP1 PGRMC1 PKHD1 PPIB TMEM31 TNFRSF13B TXNDC12 VWC2
Entrez ID		55500	819
HPRD ID		09934	03073
Ensembl ID		ENSG00000139163	ENSG00000164615
Uniprot IDs		Q86U68 Q9HBU6	P49069
PDB IDs			6SO5 8CR1
Enriched GO Terms of Interacting Partners?		Positive Regulation Of ERAD Pathway TRC Complex Regulation Of ERAD Pathway Positive Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Proteasomal Protein Catabolic Process Regulation Of Response To Endoplasmic Reticulum Stress ERAD Pathway Regulation Of Protein Catabolic Process Regulation Of Proteolysis Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Positive Regulation Of Proteasomal Protein Catabolic Process Tail-anchored Membrane Protein Insertion Into ER Membrane Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Establishment Of Protein Localization To Membrane Protein Insertion Into ER Membrane Positive Regulation Of Proteolysis Protein Targeting To ER Positive Regulation Of Protein Catabolic Process Establishment Of Protein Localization To Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Regulation Of Protein Metabolic Process Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Protein Metabolic Process Identical Protein Binding Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Protein Insertion Into Membrane Protein Targeting To Membrane Regulation Of Receptor Internalization Negative Regulation Of Store-operated Calcium Channel Activity Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Autophagosome Negative Regulation Of Transport Autophagosome Assembly Proteasomal Protein Catabolic Process Autophagosome Organization Negative Regulation Of G Protein-coupled Receptor Internalization Localization Within Membrane Regulation Of Cellular Response To Stress GET Complex Negative Regulation Of Protein Catabolic Process Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Regulation Of Receptor-mediated Endocytosis Dopamine Neurotransmitter Receptor Activity, Coupled Via Gi/Go Monocarboxylic Acid Transport Positive Regulation Of Catabolic Process Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Proteolysis Protein Catabolic Process Regulation Of Protein Modification Process	Endoplasmic Reticulum Localization Within Membrane Positive Regulation Of Protein Localization To Plasma Membrane Endoplasmic Reticulum Chaperone Complex Positive Regulation Of Protein Localization To Cell Periphery Positive Regulation Of Protein Localization To Membrane Protein Localization To Cell Periphery Digestive Tract Morphogenesis Protein-containing Complex Smooth Endoplasmic Reticulum Regulation Of Protein Localization To Plasma Membrane Regulation Of Cellular Localization Positive Regulation Of Signal Transduction Regulation Of Signal Transduction Protein Localization To Membrane
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