ETNK1 and SLC51B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ETNK1	SLC51B
Description		ethanolamine kinase 1	SLC51 subunit beta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Membrane	Plasma Membrane Membrane Basolateral Plasma Membrane Protein-containing Complex
	Molecular Function	Nucleotide Binding Ethanolamine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity	Protein Binding Bile Acid Transmembrane Transporter Activity Transmembrane Transporter Activity Protein Heterodimerization Activity
	Biological Process	Lipid Metabolic Process Phosphatidylethanolamine Biosynthetic Process Phospholipid Biosynthetic Process	Lipid Transport Bile Acid And Bile Salt Transport Regulation Of Protein Stability Bile Acid Secretion Transmembrane Transport Positive Regulation Of Protein Glycosylation Positive Regulation Of Protein Exit From Endoplasmic Reticulum Positive Regulation Of Protein Targeting To Membrane
Pathways		Synthesis of PE	Recycling of bile acids and salts
Drugs
Diseases
GWAS		Automobile speeding propensity ( 30643258) Chronotype ( 30696823) Mortality in sepsis ( 27639821) Precuneus cortex volume ( 31530798) Refractive error ( 32231278) Triglyceride levels ( 32203549)	White matter hyperintensities ( 32358547)
Interacting Genes		6 interacting genes: CAMLG SGTA SGTB SLC51B UBQLN1 UBQLN2	4 interacting genes: ASPH CYB5R1 ETNK1 LAT
Entrez ID		55500	123264
HPRD ID		09934	17811
Ensembl ID		ENSG00000139163	ENSG00000186198
Uniprot IDs		Q86U68 Q9HBU6	Q86UW2
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of ERAD Pathway TRC Complex Regulation Of ERAD Pathway Positive Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Proteasomal Protein Catabolic Process Regulation Of Response To Endoplasmic Reticulum Stress ERAD Pathway Regulation Of Protein Catabolic Process Regulation Of Proteolysis Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Positive Regulation Of Proteasomal Protein Catabolic Process Tail-anchored Membrane Protein Insertion Into ER Membrane Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Establishment Of Protein Localization To Membrane Protein Insertion Into ER Membrane Positive Regulation Of Proteolysis Protein Targeting To ER Positive Regulation Of Protein Catabolic Process Establishment Of Protein Localization To Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Regulation Of Protein Metabolic Process Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Protein Metabolic Process Identical Protein Binding Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Protein Insertion Into Membrane Protein Targeting To Membrane Regulation Of Receptor Internalization Negative Regulation Of Store-operated Calcium Channel Activity Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Autophagosome Negative Regulation Of Transport Autophagosome Assembly Proteasomal Protein Catabolic Process Autophagosome Organization Negative Regulation Of G Protein-coupled Receptor Internalization Localization Within Membrane Regulation Of Cellular Response To Stress GET Complex Negative Regulation Of Protein Catabolic Process Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Regulation Of Receptor-mediated Endocytosis Dopamine Neurotransmitter Receptor Activity, Coupled Via Gi/Go Monocarboxylic Acid Transport Positive Regulation Of Catabolic Process Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Proteolysis Protein Catabolic Process Regulation Of Protein Modification Process	Peptidyl-aspartic Acid 3-dioxygenase Activity Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Calcium-mediated Signaling TCR Signalosome Ethanolamine Kinase Activity Activation Of Store-operated Calcium Channel Activity Positive Regulation Of Store-operated Calcium Channel Activity Sarcoplasmic Reticulum Lumen Junctional Sarcoplasmic Reticulum Membrane Cortical Endoplasmic Reticulum Membrane Raft Distribution Membrane Raft Localization Cytochrome-b5 Reductase Activity, Acting On NAD(P)H Phosphatidylethanolamine Biosynthetic Process
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