NCBP3 and LENG8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NCBP3	LENG8
Description		nuclear cap binding subunit 3	leukocyte receptor cluster member 8
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Nuclear Cap Binding Complex Nuclear Speck RNA Cap Binding Complex	Nucleus Protein-containing Complex
	Molecular Function	RNA Cap Binding RNA 7-methylguanosine Cap Binding RNA Binding MRNA Binding Protein Binding	Protein Binding
	Biological Process	7-methylguanosine MRNA Capping MRNA Processing MRNA Export From Nucleus SnRNA Export From Nucleus Regulatory NcRNA-mediated Post-transcriptional Gene Silencing MRNA Transcription By RNA Polymerase II MRNA Transport Defense Response To Virus
Pathways
Drugs
Diseases
GWAS		Schizophrenia, bipolar disorder or major depressive disorder x sex interaction ( 34099189) Schizophrenia, bipolar disorder or recurrent major depressive disorder ( 34099189) Schizophrenia, bipolar disorder or recurrent major depressive disorder x sex interaction ( 34099189)
Interacting Genes		8 interacting genes: APP DAPK1 HMGB2 HNRNPH3 KPNA4 LENG8 LRRK2 SRPK2	49 interacting genes: ANKHD1 ARID5A ATN1 BAG3 C10orf55 CAMK2A CEP70 CFAP53 CIMIP2B COG2 CPSF7 CYSRT1 DMRTB1 DVL3 GSE1 HMGXB4 HNRNPM IKBKG INCA1 INTS11 KDM1A LASP1 MAGED1 MAPK1IP1L MIA3 MSX2 MYOZ3 NCBP3 NUTM2F PCID2 PER2 PRDM16 PRMT5 PRMT6 PYGO1 RHOXF2 SMARCB1 SMN1 SMYD1 SNRPA SOCS7 SUV39H1 TFG TLE5 TNIP1 TRAF4 TSG101 VGLL3 ZNF34
Entrez ID		55421	114823
HPRD ID		17116	11226
Ensembl ID		ENSG00000074356	ENSG00000167615
Uniprot IDs		Q53F19	A0A087WUE4 C9JMY0 Q96PV6
PDB IDs		8BY6
Enriched GO Terms of Interacting Partners?		Golgi-associated Vesicle RAGE Receptor Binding Cellular Response To Catecholamine Stimulus Cellular Response To Manganese Ion Response To Catecholamine Response To Manganese Ion Syntaxin-1 Binding Positive Regulation Of Programmed Cell Death Chemoattractant Activity Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Apoptotic Process Regulation Of CAMP/PKA Signal Transduction Positive Chemotaxis Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Programmed Cell Death Modulation Of Excitatory Postsynaptic Potential Amyloid-beta Complex Growth Cone Lamellipodium Cellular Response To Oxygen-containing Compound Regulation Of Response To Calcium Ion Positive Regulation Of Neuron Apoptotic Process Amylin Binding Positive Regulation Of Toll Signaling Pathway Protein Serine Kinase Activity Protein Phosphorylation DAPK1-calmodulin Complex Positive Regulation Of Autophagic Cell Death Cellular Response To Curcumin Caveola Neck GTP-dependent Protein Kinase Activity Wnt Signalosome Assembly Response To Oxidative Stress Phosphorylation Regulation Of Apoptotic Signaling Pathway Acetylcholine Receptor Activator Activity Response To Stress Regulation Of Response To Endoplasmic Reticulum Stress Macromolecule Metabolic Process Regulation Of Calcium-mediated Signaling Lipoprotein Particle Positive Regulation Of Protein Import Defense Response To Gram-negative Bacterium Protein Serine/threonine Kinase Activity Non-sequence-specific DNA Binding, Bending Nucleus Organization Negative Regulation Of Late Endosome To Lysosome Transport Amphisome Peroxidase Inhibitor Activity Negative Regulation Of Protein Processing Involved In Protein Targeting To Mitochondrion	Identical Protein Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nucleus Histone H3 Methyltransferase Activity Transcription Corepressor Activity Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Histone Arginine N-methyltransferase Activity Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Histone H4R3 Methyltransferase Activity Chromatin Remodeling Protein Binding Negative Regulation Of RNA Metabolic Process Chromatin Organization Methyltransferase Activity Regulation Of Gene Expression Histone Methyltransferase Activity Transcription Coactivator Activity Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Histone H3K9me2 Methyltransferase Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Methylation Protein-arginine N-methyltransferase Activity Histone H3K9 Methyltransferase Activity Regulation Of Metabolic Process Nucleoplasm Circadian Rhythm Negative Regulation Of Macromolecule Biosynthetic Process Transcription Cis-regulatory Region Binding Circadian Regulation Of Gene Expression P53 Binding Epigenetic Regulation Of Gene Expression Regulation Of Signal Transduction Negative Regulation Of Biosynthetic Process Developmental Process DNA-templated Transcription Termination
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