NCBP3 and HNRNPH3

Number of citations of the paper that reports this interaction (PubMedID 22365833)
0

Data Source:
BioGRID (two hybrid, two hybrid)

		NCBP3	HNRNPH3
Description		nuclear cap binding subunit 3	heterogeneous nuclear ribonucleoprotein H3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Nuclear Cap Binding Complex Nuclear Speck RNA Cap Binding Complex	Nucleus Nucleoplasm Spliceosomal Complex Ribonucleoprotein Complex
	Molecular Function	RNA Cap Binding RNA 7-methylguanosine Cap Binding RNA Binding MRNA Binding Protein Binding	Nucleic Acid Binding RNA Binding Protein Binding
	Biological Process	7-methylguanosine MRNA Capping MRNA Processing MRNA Export From Nucleus SnRNA Export From Nucleus Regulatory NcRNA-mediated Post-transcriptional Gene Silencing MRNA Transcription By RNA Polymerase II MRNA Transport Defense Response To Virus	MRNA Splicing, Via Spliceosome RNA Processing MRNA Processing RNA Splicing Epithelial Cell Differentiation Regulation Of RNA Splicing
Pathways
Drugs			Copper
Diseases
GWAS		Schizophrenia, bipolar disorder or major depressive disorder x sex interaction ( 34099189) Schizophrenia, bipolar disorder or recurrent major depressive disorder ( 34099189) Schizophrenia, bipolar disorder or recurrent major depressive disorder x sex interaction ( 34099189)
Interacting Genes		8 interacting genes: APP DAPK1 HMGB2 HNRNPH3 KPNA4 LENG8 LRRK2 SRPK2	100 interacting genes: ADORA2A ANXA11 CCL13 CHERP CRMP1 DDX17 DDX5 EEF1G ERG ERG28 HNRNPA0 HNRNPA1 HNRNPD HNRNPF HNRNPH1 HNRNPU HNRNPUL1 IL7R KAT5 MAPK6 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NCBP3 PIM2 RBM4 RPS4X SLC22A2 TTR UTP14A ZMYM2
Entrez ID		55421	3189
HPRD ID		17116	03818
Ensembl ID		ENSG00000074356	ENSG00000096746
Uniprot IDs		Q53F19	B4DHY1 P31942 Q53F48
PDB IDs		8BY6
Enriched GO Terms of Interacting Partners?		Golgi-associated Vesicle RAGE Receptor Binding Cellular Response To Catecholamine Stimulus Cellular Response To Manganese Ion Response To Catecholamine Response To Manganese Ion Syntaxin-1 Binding Positive Regulation Of Programmed Cell Death Chemoattractant Activity Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Apoptotic Process Regulation Of CAMP/PKA Signal Transduction Positive Chemotaxis Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Programmed Cell Death Modulation Of Excitatory Postsynaptic Potential Amyloid-beta Complex Growth Cone Lamellipodium Cellular Response To Oxygen-containing Compound Regulation Of Response To Calcium Ion Positive Regulation Of Neuron Apoptotic Process Amylin Binding Positive Regulation Of Toll Signaling Pathway Protein Serine Kinase Activity Protein Phosphorylation DAPK1-calmodulin Complex Positive Regulation Of Autophagic Cell Death Cellular Response To Curcumin Caveola Neck GTP-dependent Protein Kinase Activity Wnt Signalosome Assembly Response To Oxidative Stress Phosphorylation Regulation Of Apoptotic Signaling Pathway Acetylcholine Receptor Activator Activity Response To Stress Regulation Of Response To Endoplasmic Reticulum Stress Macromolecule Metabolic Process Regulation Of Calcium-mediated Signaling Lipoprotein Particle Positive Regulation Of Protein Import Defense Response To Gram-negative Bacterium Protein Serine/threonine Kinase Activity Non-sequence-specific DNA Binding, Bending Nucleus Organization Negative Regulation Of Late Endosome To Lysosome Transport Amphisome Peroxidase Inhibitor Activity Negative Regulation Of Protein Processing Involved In Protein Targeting To Mitochondrion	MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Extracellular Vesicle Negative Regulation Of Translation Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process MRNA Destabilization RNA Destabilization Positive Regulation Of MRNA Catabolic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Cytokine Production Regulation Of MRNA Stability Regulation Of Translation Negative Regulation Of Angiogenesis Regulation Of MRNA Metabolic Process Negative Regulation Of Cell Migration Negative Regulation Of Vasculature Development Regulation Of RNA Stability Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Cell Motility Regulation Of Metabolic Process Regulation Of Angiogenesis Negative Regulation Of Locomotion Regulation Of Vasculature Development Negative Regulation Of Multicellular Organismal Process Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Developmental Process Negative Regulation Of Protein Metabolic Process Regulation Of Endothelial Cell Migration Extracellular Space Negative Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Endothelial Cell Migration Regulation Of Cell Migration Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Cellular Response To Growth Factor Stimulus
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