PCMTD2 and TRIP13

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		PCMTD2	TRIP13
Description		protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2	thyroid hormone receptor interactor 13
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Male Germ Cell Nucleus Nucleus Chromosome
	Molecular Function	Protein-L-isoaspartate (D-aspartate) O-methyltransferase Activity Protein Binding	Nucleotide Binding Transcription Coregulator Activity Protein Binding ATP Binding ATP Hydrolysis Activity Identical Protein Binding
	Biological Process		Oocyte Maturation Double-strand Break Repair Transcription By RNA Polymerase II Mitotic Spindle Assembly Checkpoint Signaling Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Meiosis I Female Meiosis I Spermatogenesis Spermatid Development Cell Differentiation Oogenesis Meiotic Cell Cycle Meiotic Recombination Checkpoint Signaling
Pathways
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Bitter beverage consumption ( 31046077) Bitter non-alcoholic beverage consumption ( 31046077) Caffeine consumption from coffee or tea ( 33287642) Caffeine consumption from tea ( 33287642) Clozapine-induced cytotoxicity ( 25656473) Coffee consumption ( 31046077) Estimated glomerular filtration rate ( 31152163) LDL cholesterol levels ( 32203549)	Pancreatic cancer ( 25086665)
Interacting Genes		5 interacting genes: ACSL6 ATP13A2 PIGP TRIP13 VAC14	113 interacting genes: ACTMAP ADAM15 AMDHD2 ANKRD10 ARL11 ARSA ASB13 BKGD BUB1B C4orf33 CARD14 CD99 CDC20 CDIN1 CEP170B CFP CLIP4 COMT CRMP1 CRYBA2 CYB5R2 DCTN3 DDAH2 DIP2A DPYSL4 DTX2 EEF2KMT FBLN5 FBXO8 FILNC1 FNDC3B GALT GLYCTK GPRIN2 GPSM1 HDHD3 IGFN1 IL2RB INCA1 INTS11 KRTAP12-1 KRTAP12-2 KRTAP12-4 KRTAP26-1 KRTAP3-2 KRTAP6-1 KRTAP6-2 KYAT1 LASP1 LNX1 LOXL4 LRR1 LRRC61 M1AP MAD2L1 MAD2L1BP MBLAC1 MEAK7 METTL15 MGAT5B MORN3 MPPED2 MVP MYEOV NIF3L1 NME4 NTAQ1 PARP11 PAX9 PBLD PCMTD2 PCSK5 PELI1 PLAC8 PLK3 PLSCR3 PLSCR4 POLR2L PPP2CA PRKAA2 PRKN PRR13 PSMB8 QARS1 RBPMS RHOXF2 RNF4 SCP2 SDCBP SEC24A SELENBP1 SEMA3B SEMA4G SHARPIN SIGLEC5 SMUG1 SPMIP9 SPRYD7 SSC4D STAMBP STAMBPL1 SUMO2 TENT5B THRB TINAGL1 TNRC6A TPT1 UBE2I VDR VENTX ZMYM5 ZNF34 ZNF655
Entrez ID		55251	9319
HPRD ID		12764	05145
Ensembl ID		ENSG00000203880	ENSG00000071539
Uniprot IDs		Q9NV79	Q15645
PDB IDs			5VQ9 5VQA 5WC2 6F0X 6LK0 7L9P
Enriched GO Terms of Interacting Partners?		Lipid Biosynthetic Process Organophosphate Biosynthetic Process Spermine Transmembrane Transport ABC-type Polyamine Transporter Activity PAS Complex Phosphatidylinositol Biosynthetic Process Meiotic Recombination Checkpoint Signaling Organophosphate Metabolic Process Polyamine Transmembrane Transporter Activity Extracellular Vesicle Biogenesis Spermine Transport Extracellular Exosome Biogenesis P-type Ion Transporter Activity Late Endosome Membrane Negative Regulation Of Lysosomal Protein Catabolic Process P-type Transmembrane Transporter Activity Regulation Of Autophagosome Size Cupric Ion Binding Glycerophospholipid Biosynthetic Process Phospholipid Biosynthetic Process Phosphatidylinositol N-acetylglucosaminyltransferase Activity Phosphatidylinositol Metabolic Process Female Meiosis I Meiotic Cell Cycle Checkpoint Signaling Lipid Metabolic Process Regulation Of Chaperone-mediated Autophagy Polyamine Transmembrane Transport Glycerophospholipid Metabolic Process Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex Presynaptic Endosome Negative Regulation Of Meiotic Nuclear Division Cellular Response To Manganese Ion Arachidonate-CoA Ligase Activity ATPase-coupled Monoatomic Cation Transmembrane Transporter Activity Regulation Of Lysosomal Protein Catabolic Process Glycerolipid Metabolic Process Phospholipid Metabolic Process ATP Hydrolysis Activity Long-chain Fatty Acid-CoA Ligase Activity Phosphate-containing Compound Metabolic Process Response To Manganese Ion Autophagosome-lysosome Fusion Positive Regulation Of Exosomal Secretion ATP Binding Negative Regulation Of Meiotic Cell Cycle Female Meiotic Nuclear Division Long-chain Fatty-acyl-CoA Biosynthetic Process Regulation Of Exosomal Secretion Synaptonemal Complex Assembly Endoplasmic Reticulum	Protein Binding Mitotic Checkpoint Complex Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds Protein K6-linked Ubiquitination Intermediate Filament
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