PPP2R3A and PPP5C

Number of citations of the paper that reports this interaction (PMID 11504734)
15

Data Source:
HPRD (in vivo)

		PPP2R3A	PPP5C
Gene Name		protein phosphatase 2, regulatory subunit B, alpha	protein phosphatase 5, catalytic subunit
Image
Gene Ontology Annotations	Cellular Component	Protein Phosphatase Type 2A Complex	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Neuron Projection Neuronal Cell Body Intracellular Membrane-bounded Organelle
	Molecular Function	Calcium Ion Binding Protein Binding Protein Phosphatase Type 2A Regulator Activity	RNA Binding Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Signal Transducer Activity Protein Binding Lipid Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Eye Photoreceptor Cell Differentiation Protein Dephosphorylation Somatic Muscle Development Positive Regulation Of Protein Catabolic Process Regulation Of Catalytic Activity Somite Development Negative Regulation Of Canonical Wnt Signaling Pathway Wnt Signaling Pathway Involved In Somitogenesis Regulation Of Cell Motility Involved In Somitogenic Axis Elongation Positive Regulation Of Canonical Wnt Signaling Pathway	DNA Repair Transcription, DNA-templated Protein Dephosphorylation Mitotic Nuclear Division Signal Transduction Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Response To Morphine Protein Heterooligomerization
Pathways
Drugs
Diseases
GWAS		Anticoagulant levels ( 22216198)
Protein-Protein Interactions		8 interactors: AKAP9 ATXN7L2 CDC6 HMGB1 PPP2CA PPP2R4 PPP5C RBL1	22 interactors: APP CDC16 CDC27 CDK20 CHORDC1 CPNE1 CPNE2 CPNE4 CRY2 CSE1L DISC1 EGFR ESR2 GNA12 GNA13 HSP90AA1 HTR2A MAP3K5 MAP3K7 MAPT PPP2R1A PPP2R3A
Entrez ID		5523	5536
HPRD ID		09225	02805
Ensembl ID		ENSG00000073711	ENSG00000011485
Uniprot IDs		Q06190	B7Z1I1 P53041
PDB IDs		4I5J 4I5K	1A17 1S95 1WAO 2BUG 3H60 3H61 3H62 3H63 3H64 3H66 3H67 3H68 3H69
Enriched GO Terms of Interacting Partners?		Mitotic Cell Cycle Cell Cycle Mitotic Cell Cycle Process Organelle Organization Cell Cycle Process Regulation Of Phosphorus Metabolic Process Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Catalytic Activity Positive Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Phosphorylation Mitotic Spindle Organization In Nucleus Negative Regulation Of Apoptotic Cell Clearance Negative Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Regulation Of DNA Replication Protein Heterooligomerization Positive Regulation Of Metabolic Process Negative Regulation Of DNA-templated Transcription, Initiation Negative Regulation Of Transcription Initiation From RNA Polymerase II Promoter Regulation Of Kinase Activity Base-excision Repair, DNA Ligation Negative Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Traversing Start Control Point Of Mitotic Cell Cycle Negative Regulation Of Protein Dephosphorylation Positive Regulation Of Protein Modification Process Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Protein Dephosphorylation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cellular Metabolic Process Negative Regulation Of Phosphoprotein Phosphatase Activity Mitotic Nuclear Envelope Reassembly DNA Metabolic Process Regulation Of Protein Phosphorylation DNA Ligation Involved In DNA Repair DNA Replication Checkpoint Protein Heterotrimerization Regulation Of Apoptotic Cell Clearance Response To Organic Substance Nuclear Envelope Reassembly Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Negative Regulation Of Phagocytosis Mitotic Nuclear Division Nucleobase-containing Compound Metabolic Process Positive Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization DNA Ligation See more	Regulation Of Catalytic Activity Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Protein Catabolic Process Regulation Of Cellular Component Organization Cell Death Death Regulation Of Metabolic Process Regulation Of Protein Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Kinase Activity Regulation Of Signal Transduction Regulation Of MAP Kinase Activity Positive Regulation Of Proteolysis Positive Regulation Of Transferase Activity Positive Regulation Of Protein Modification Process Apoptotic Process Regulation Of Signaling Programmed Cell Death Regulation Of Proteolysis Regulation Of Phosphorus Metabolic Process Regulation Of Protein Phosphorylation Positive Regulation Of Catalytic Activity Intracellular Receptor Signaling Pathway Activation Of MAPKK Activity Positive Regulation Of Metabolic Process Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of MAP Kinase Activity Positive Regulation Of Protein Catabolic Process Negative Regulation Of Signaling Negative Regulation Of Catalytic Activity Metal Ion Homeostasis Positive Regulation Of Phospholipase Activity Cellular Protein Metabolic Process Signal Transduction Positive Regulation Of Signal Transduction Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Phospholipase Activity Chemical Homeostasis Positive Regulation Of Lipase Activity Regulation Of Phosphorylation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Negative Regulation Of Protein Metabolic Process Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Anatomical Structure Morphogenesis Intracellular Signal Transduction Positive Regulation Of Protein Serine/threonine Kinase Activity Cell Surface Receptor Signaling Pathway See more
Tagcloud ?		aza basonuclin bnc1 childhood demonstrating deoxycytidine epigenetic epigenetically fbln2 fibulin frequent frequently homeobox identification inactivated inactivation leukemia lymphoblastic methylated methylation microarray msh msx1 noti restored screens showing thrb whilst	cantharidin catalytic communities date desired fluorescent greatly libraries microcystin okadaic optimization pharmaceutical phosphatase phosphatases pp1 pp1alpha pp1calpha ppp1c representative robust screen selectively share simultaneously threonine z
Tagcloud (Difference) ?		aza basonuclin bnc1 childhood demonstrating deoxycytidine epigenetic epigenetically fbln2 fibulin frequent frequently homeobox identification inactivated inactivation leukemia lymphoblastic methylated methylation microarray msh msx1 noti restored screens showing thrb whilst	cantharidin catalytic communities date desired fluorescent greatly libraries microcystin okadaic optimization pharmaceutical phosphatase phosphatases pp1 pp1alpha pp1calpha ppp1c representative robust screen selectively share simultaneously threonine z
Tagcloud (Intersection) ?