GOLPH3L and B4GALT4

Number of citations of the paper that reports this interaction (PubMedID 34473204)
68

Data Source:
BioGRID (pull down)

		GOLPH3L	B4GALT4
Description		golgi phosphoprotein 3 like	beta-1,4-galactosyltransferase 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Trans-Golgi Network Cytosol Membrane Golgi Cisterna Golgi Cisterna Membrane Trans-Golgi Network Membrane	Golgi Membrane Extracellular Region Golgi Apparatus Membrane
	Molecular Function	Protein Binding Lipid Binding Phosphatidylinositol-4-phosphate Binding Cargo Adaptor Activity	N-acetyllactosamine Synthase Activity Protein Binding Galactosyltransferase Activity Transferase Activity Glycosyltransferase Activity UDP-galactosyltransferase Activity Metal Ion Binding
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Organization Golgi To Plasma Membrane Protein Transport Golgi Vesicle Budding Positive Regulation Of Protein Secretion Protein Targeting To Golgi Apparatus	Lactosylceramide Biosynthetic Process Carbohydrate Metabolic Process Protein Glycosylation Lipid Metabolic Process Membrane Lipid Metabolic Process Keratan Sulfate Proteoglycan Biosynthetic Process Glycosylation
Pathways			Keratan sulfate biosynthesis N-Glycan antennae elongation
Drugs			N-Acetylglucosamine
Diseases
GWAS		Basal cell carcinoma ( 31174203) Body mass index ( 26426971) Caffeine consumption from coffee ( 33287642) Caffeine consumption from coffee or tea ( 33287642) Caffeine consumption from tea ( 33287642) Chronotype ( 30696823) Keratinocyte cancer (MTAG) ( 31174203) Morning person ( 30696823) Neutrophil percentage of white cells ( 27863252) Prostate cancer ( 25217961) Refractive error ( 32231278) Rhegmatogenous retinal detachment ( 23585552) Triglyceride levels ( 32203549) Urate levels ( 31578528)	Clozapine-induced cytotoxicity ( 25656473) First year height change in growth hormone-treated short stature ( 32652002) Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042) Survival in pancreatic cancer ( 28470677)
Interacting Genes		26 interacting genes: ARL6IP1 B4GALT4 C1GALT1 CANT1 DIPK2A EBAG9 EXT1 FAM20B FAM3C GALNT2 GALNT6 GALNT7 GCNT1 GLG1 GLT8D1 GOLIM4 GOLM2 HTT LNX1 MAN1B1 MGAT2 PGAP4 POMGNT1 TPST1 TPST2 ZDHHC17	2 interacting genes: GOLPH3 GOLPH3L
Entrez ID		55204	8702
HPRD ID		17048	04930
Ensembl ID		ENSG00000143457	ENSG00000121578
Uniprot IDs		Q9H4A5	B2RAZ5 B3KM35 E7ETS9 O60513
PDB IDs
Enriched GO Terms of Interacting Partners?		Golgi Apparatus Golgi Membrane Glycoprotein Metabolic Process Glycosyltransferase Activity Glycoprotein Biosynthetic Process Protein Glycosylation Macromolecule Glycosylation Glycosylation Carbohydrate Derivative Metabolic Process Carbohydrate Derivative Biosynthetic Process Protein O-linked Glycosylation Transferase Activity Protein O-linked Glycosylation Via N-acetyl-galactosamine Protein Modification Process Protein Metabolic Process Macromolecule Biosynthetic Process Polypeptide N-acetylgalactosaminyltransferase Activity Membrane Proteoglycan Biosynthetic Process Protein-tyrosine Sulfotransferase Activity Carbohydrate Binding Proteoglycan Metabolic Process Macromolecule Metabolic Process Manganese Ion Binding Golgi Cisterna Membrane 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Carbohydrate Metabolic Process Sulfation Acetylglucosaminyltransferase Activity UDP-glycosyltransferase Activity Leukocyte Tethering Or Rolling Golgi Lumen Leukocyte Adhesion To Vascular Endothelial Cell Viral Protein Processing Basement Membrane Organization Bone Morphogenesis Lymphocyte Adhesion To Endothelial Cell Of High Endothelial Venule Perichondral Bone Morphogenesis Sweat Gland Development Smoothened Signaling Pathway Involved In Lung Development Alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase Activity Peptidyl-tyrosine Sulfation Perforant Pathway To Dendrate Granule Cell Synapse Golgi Stack N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase Activity Mesenchymal Cell Differentiation Involved In Bone Development Stomach Development Heparan Sulfate N-acetylglucosaminyltransferase Activity Trans-Golgi Network Beta-1,3-galactosyl-O-glycosyl-glycoprotein Beta-1,6-N-acetylglucosaminyltransferase Activity	Golgi Vesicle Budding Cargo Adaptor Activity Protein Targeting To Golgi Apparatus Golgi Cisterna Phosphatidylinositol-4-phosphate Binding Golgi To Plasma Membrane Protein Transport Vesicle Budding From Membrane Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Establishment Of Protein Localization To Plasma Membrane Golgi To Plasma Membrane Transport Golgi Cisterna Membrane Post-Golgi Vesicle-mediated Transport Golgi Organization Vesicle-mediated Transport To The Plasma Membrane Positive Regulation Of Protein Secretion Asymmetric Golgi Ribbon Formation Protein Localization To Plasma Membrane Trans-Golgi Network Cell Adhesion Molecule Production Cellular Response To Rapamycin Protein Targeting Establishment Of Protein Localization To Membrane Protein Retention In Golgi Apparatus Protein Localization To Cell Periphery Epsilon DNA Polymerase Complex Positive Regulation Of Protein Transport Regulation Of Protein Secretion Response To Rapamycin Golgi Vesicle Transport Positive Regulation Of Secretion By Cell Vesicle Organization Positive Regulation Of Secretion Positive Regulation Of Establishment Of Protein Localization Protein Localization To Membrane Lipid Binding Establishment Of Protein Localization To Organelle Golgi Ribbon Formation Cellular Response To Ether ATAC Complex Regulation Of Protein Transport Positive Regulation Of Protein Localization Negative Regulation Of Interleukin-12 Production Leukocyte Tethering Or Rolling DNA-directed DNA Polymerase Activity Response To Ether Localization Within Membrane Regulation Of Establishment Of Protein Localization Leukocyte Adhesion To Vascular Endothelial Cell Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Secretion By Cell
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